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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
clinical decrease » clinical disease (Expand Search), linear decrease (Expand Search), clinical areas (Expand Search)
clinical case » clinical cases (Expand Search), clinical care (Expand Search), clinical course (Expand Search)
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19401
Table 1_Molecular assessment of splicing variants in a cohort of patients with inborn errors of immunity: methodological approach and interpretation remarks.docx
Published 2025“…Molecular validation was required only in the cases of genes of uncertain significance (GUS), high homology pseudogenes or incompatible clinical phenotype. …”
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19402
Table 3_The T385M STAT1 gain-of-function mutation confers the most severe disease outcomes.docx
Published 2025“…Mutations in the DNA-binding domain (DBD) have previously been associated with poor outcomes, but the contributions of specific variants to clinical phenotype remain unexplored.</p>Methods<p>We performed a systematic literature review to identify patients with confirmed STAT1 GOF mutations, integrating new cases with a previously reported international cohort. …”
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19403
Table1_Wearable Patch ECG monitors and transesophageal electrophysiological study for diagnosing palpitations of unknown origin.doc
Published 2024“…Of the 569 patients, 102 refused to undergo Patch ECG monitors, and 467 patients completed the entire study process. Among them, 379 cases (66.61%) were clinically diagnosed as arrhythmias. …”
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19404
Table 1_The T385M STAT1 gain-of-function mutation confers the most severe disease outcomes.docx
Published 2025“…Mutations in the DNA-binding domain (DBD) have previously been associated with poor outcomes, but the contributions of specific variants to clinical phenotype remain unexplored.</p>Methods<p>We performed a systematic literature review to identify patients with confirmed STAT1 GOF mutations, integrating new cases with a previously reported international cohort. …”
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19405
Table 2_The T385M STAT1 gain-of-function mutation confers the most severe disease outcomes.docx
Published 2025“…Mutations in the DNA-binding domain (DBD) have previously been associated with poor outcomes, but the contributions of specific variants to clinical phenotype remain unexplored.</p>Methods<p>We performed a systematic literature review to identify patients with confirmed STAT1 GOF mutations, integrating new cases with a previously reported international cohort. …”
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19406
Data Sheet 1_Balancing conservation and community needs: challenges, threats, and socioeconomic disparities in Kakamega Forest, Kenya.docx
Published 2025“…Illegal logging emerged as the most significant threat to KFE, regardless of wealth category, followed by a lack of awareness of conservation efforts, with significant differences in perception across wealth categories. …”
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19407
Effect of Gasdermin-D inhibition on expression of phenotypic transition markers in CER treated VSMCs during Vascular Calcification.
Published 2025“…(B) Summarized bar graph showed DIS significantly decreased calcium deposition in CER treated P<sub>i</sub>-induced VSMCs. …”
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19408
Data Sheet 1_Integrated transcriptomics and machine learning reveal REN as a dual regulator of tumor stemness and NK cell evasion in Wilms tumor progression.docx
Published 2025“…Introduction<p>Wilms tumor (WT) is the most common pediatric kidney cancer, which presents significant therapeutic challenges, particularly in high-risk cases, due to chemotherapy resistance and immunosuppressive tumor microenvironments (TMEs). …”
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19409
Image 1_Integrated transcriptomics and machine learning reveal REN as a dual regulator of tumor stemness and NK cell evasion in Wilms tumor progression.tif
Published 2025“…Introduction<p>Wilms tumor (WT) is the most common pediatric kidney cancer, which presents significant therapeutic challenges, particularly in high-risk cases, due to chemotherapy resistance and immunosuppressive tumor microenvironments (TMEs). …”
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19410
Supplementary file 1_Long-term trends in the burden of multiple myeloma in China: a Joinpoint regression and age-period-cohort analysis based on GBD 2021.docx
Published 2025“…</p>Results<p>It is estimated that in 2021, there were 17,250 new cases of MM in China, with 47,004 cases and 12,984 deaths. …”
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19411
Table 1_Integrated transcriptomics and machine learning reveal REN as a dual regulator of tumor stemness and NK cell evasion in Wilms tumor progression.xlsx
Published 2025“…Introduction<p>Wilms tumor (WT) is the most common pediatric kidney cancer, which presents significant therapeutic challenges, particularly in high-risk cases, due to chemotherapy resistance and immunosuppressive tumor microenvironments (TMEs). …”
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19412
Table 1_Long-term trends in the burden of multiple myeloma in China: a Joinpoint regression and age-period-cohort analysis based on GBD 2021.docx
Published 2025“…</p>Results<p>It is estimated that in 2021, there were 17,250 new cases of MM in China, with 47,004 cases and 12,984 deaths. …”
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19413
Table 5_Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.xlsx
Published 2025“…This study highlights the challenges faced in managing IHD and calls for governments and institutions to adopt multidimensional public health strategies encompassing age, risk factors, gender, and predictive models to address the growing number of cases and other health problems. These findings will guide health policies to effectively control clinical stress in IHD by prioritizing regional risk factors for targeted interventions and individualized prevention for high-risk populations, while also ensuring efficient use of health resources.…”
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19414
Table 1_Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.csv
Published 2025“…This study highlights the challenges faced in managing IHD and calls for governments and institutions to adopt multidimensional public health strategies encompassing age, risk factors, gender, and predictive models to address the growing number of cases and other health problems. These findings will guide health policies to effectively control clinical stress in IHD by prioritizing regional risk factors for targeted interventions and individualized prevention for high-risk populations, while also ensuring efficient use of health resources.…”
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19415
Table 4_Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.csv
Published 2025“…This study highlights the challenges faced in managing IHD and calls for governments and institutions to adopt multidimensional public health strategies encompassing age, risk factors, gender, and predictive models to address the growing number of cases and other health problems. These findings will guide health policies to effectively control clinical stress in IHD by prioritizing regional risk factors for targeted interventions and individualized prevention for high-risk populations, while also ensuring efficient use of health resources.…”
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19416
Table 10_Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.docx
Published 2025“…This study highlights the challenges faced in managing IHD and calls for governments and institutions to adopt multidimensional public health strategies encompassing age, risk factors, gender, and predictive models to address the growing number of cases and other health problems. These findings will guide health policies to effectively control clinical stress in IHD by prioritizing regional risk factors for targeted interventions and individualized prevention for high-risk populations, while also ensuring efficient use of health resources.…”
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19417
Table 9_Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.docx
Published 2025“…This study highlights the challenges faced in managing IHD and calls for governments and institutions to adopt multidimensional public health strategies encompassing age, risk factors, gender, and predictive models to address the growing number of cases and other health problems. These findings will guide health policies to effectively control clinical stress in IHD by prioritizing regional risk factors for targeted interventions and individualized prevention for high-risk populations, while also ensuring efficient use of health resources.…”
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19418
Table 8_Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.docx
Published 2025“…This study highlights the challenges faced in managing IHD and calls for governments and institutions to adopt multidimensional public health strategies encompassing age, risk factors, gender, and predictive models to address the growing number of cases and other health problems. These findings will guide health policies to effectively control clinical stress in IHD by prioritizing regional risk factors for targeted interventions and individualized prevention for high-risk populations, while also ensuring efficient use of health resources.…”
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19419
Table 7_Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.xlsx
Published 2025“…This study highlights the challenges faced in managing IHD and calls for governments and institutions to adopt multidimensional public health strategies encompassing age, risk factors, gender, and predictive models to address the growing number of cases and other health problems. These findings will guide health policies to effectively control clinical stress in IHD by prioritizing regional risk factors for targeted interventions and individualized prevention for high-risk populations, while also ensuring efficient use of health resources.…”
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19420
Table 6_Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.xlsx
Published 2025“…This study highlights the challenges faced in managing IHD and calls for governments and institutions to adopt multidimensional public health strategies encompassing age, risk factors, gender, and predictive models to address the growing number of cases and other health problems. These findings will guide health policies to effectively control clinical stress in IHD by prioritizing regional risk factors for targeted interventions and individualized prevention for high-risk populations, while also ensuring efficient use of health resources.…”