Showing 21,121 - 21,140 results of 21,342 for search '(( significant decrease decrease ) OR ( significant ((clinical decrease) OR (linear decrease)) ))', query time: 0.59s Refine Results
  1. 21121

    DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

    Published 2025
    “…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …”
  2. 21122

    DNA damage protecting effects of PEExCC. by Srabonti Saha (17452756)

    Published 2025
    “…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …”
  3. 21123

    <i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation by jin guan (21792620)

    Published 2025
    “…Invasive strains exhibited significantly enhanced serum resistance (>17-fold survival in 75% isolates) and HeLa cell invasive ability (minimum bacterial loads 3.93 × 10⁵ CFU/mL) compared to non-invasive strains (< 9.8-fold survival; maximum bacterial loads 1.47 × 10⁵ CFU/mL). …”
  4. 21124

    Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

    Published 2025
    “…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…”
  5. 21125

    Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx by Youqiong Xu (18161893)

    Published 2025
    “…PreMetS [OR = 1.38, 95%CI: 1.16–1.64] and MetS [OR = 1.61, 95%CI: 1.32–1.97] were associated with a significantly higher risk of multiple comorbidities compared with the normal population, and the risk of multiple comorbidities tended to increase as the number of metabolic disorder components increased (p < 0.001). …”
  6. 21126

    Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip... by Xuan Chen (158617)

    Published 2025
    “…Among medium- and long-chain fatty acids, the H-RES-HMB group showed significantly decreased SFAs (C17:0 and C18:0) (p < 0.05) and significantly increased MUFAs (C15:1N5 and C18:1N9) and PUFAs (C18:2N6, C18:3N6, C18:3N3, C20:3N6, and C20:3N3) (p < 0.05). …”
  7. 21127

    H2AK119ub is neurodevelopmentally enriched within H3K9ac-positive euchromatin. by Aditya Parmar (22331873)

    Published 2025
    “…(F) Heatmaps depicting H3K9ac CUT&RUN data within loci with no change, increased or decreased H2AK119ub over neurodevelopment. (G) Heatmaps depicting H3K9ac CUT&RUN data within loci harboring both H2AK119ub and H3K27me3. …”
  8. 21128

    Data Sheet 1_Endophytic and antagonistic Bacillus amyloliquefaciens 8SE-IF1-derived nanoparticles encumber phytopathogenic oomycetes, fungi, bacteria, and viruses with enhanced gro... by A. Mary Sharmila (21898730)

    Published 2025
    “…The water-diffusible extract (WDE) of Ba-8SE-IF1 significantly inhibited the mycelial growth of Pythium aphanidermatum (44.6%), Phytophthora nicotianae (60.1%), Fusarium oxysporum f. sp. lycopersici (65.5%), and Colletotrichum gloeosporioides (66.7%) in poisoned food assays; the growth of Ralstonia solanacearum and Xanthomonas campestris in the agar well method (inhibition zones of 20.25 mm and 28.52 mm, respectively); and decreased the symptoms produced by tomato spotted wilt virus (TSWV) in local lesion host (68.3%) and tomato leaf curl New Delhi virus (ToLCNDV) in tomato plants (66.1%). …”
  9. 21129

    Time-limited downregulation of cerebellar neurophysiological processes in NHPs during LACV infection. by Olga A. Maximova (3115716)

    Published 2025
    “…The color scale is based on the significance (-log<sub>10</sub> p-adj). The gene ontology (GO) sources: BP, Biological Process; CC, Cellular Component; and MF, Molecular Function (terms are highlighted by respective colors). …”
  10. 21130

    Risk of bias across 22 included studie. by Kuo-Chuan Hung (8587392)

    Published 2024
    “…</p><p>Results</p><p>A meta-analysis of 22 RCTs (n = 3,463) showed that ketamine/esketamine significantly decreased PPD risk at 1- (risk ratio [RR], 0.41; 95% confidence interval [CI], 0.3–0.57) and 4–6-week (RR, 0.47; 95%CI, 0.35–0.63) follow-ups. …”
  11. 21131

    Table 1_Avoiding touching until 60 min—contamination of transdermal estradiol gel after physical contact.docx by Yi Cao (229829)

    Published 2025
    “…In the estradiol gel group, estradiol levels remained stable within the first 30 min (p >0.05), rapidly decreased at 60 min (p <0.001) and remained stable from 60 min to 120 min (p >0.05). …”
  12. 21132

    Figure 2 from Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in <i>EGFR</i>- and <i>KRAS</i>-Mutant Lung Cancer by Xiaoxiao Sun (20589448)

    Published 2025
    “…<p>PRMT1 knockdown decreases persistence in STAT1-high <i>EGFR</i><sup><i>mut</i></sup> and <i>KRAS</i><sup><i>G12C</i></sup> lung cancer cell lines. …”
  13. 21133

    List of primers used in quantitative RT-PCR. by Tarek A. Essa (22430744)

    Published 2025
    “…The results demonstrated that NPs significantly reduced basal rot symptoms and decreased the Area Under the Disease Progress Curve (AUDPC) values. …”
  14. 21134

    Table 2_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.csv by Siying Wei (5990276)

    Published 2025
    “…However, the pandemic significantly slowed the decline in low- and low-middle SDI regions.…”
  15. 21135

    Image 4_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif by Shaolian Zang (11987905)

    Published 2025
    “…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”
  16. 21136

    Table 1_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx by Chuanchuan Wang (12228518)

    Published 2024
    “…Association analysis showed that all six SNPs were significantly associated with milk protein percentage. …”
  17. 21137

    Image 4_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... by Yun Xu (139234)

    Published 2025
    “…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …”
  18. 21138

    Table 6_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx by Chuanchuan Wang (12228518)

    Published 2024
    “…Association analysis showed that all six SNPs were significantly associated with milk protein percentage. …”
  19. 21139

    Image 3_HIV risk and influence factors among MSM who had sought sexual partners in core venues: a continuous sentinel surveillance in 2010–2022.png by Zijie Yang (6330086)

    Published 2024
    “…</p>Conclusion<p>Following the implementation of differentiated venue-based interventions, the risk of HIV among MSM who had sought sexual partners in core venues decreased to a level comparable to that of MSM who had not. …”
  20. 21140

    The role of Cathepsin inhibitors in RGC damage in hypoxic retina. by Emi Nakajima (21703141)

    Published 2025
    “…Treatment with neither Odanacatib nor SID26681509 reduced the percentage of PI-positive RGCs, whereas the positive control SNJ-1945 significantly decreased the percentage. Data are means ± SD (n = 3). …”