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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
concern decrease » content decreased (Expand Search)
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19621
Video 8_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4
Published 2024“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”
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19622
Data Sheet 1_Structural and functional characterization of gut microbiota in dyslipidemic patients from high-altitude Tibetan pastoral areas.pdf
Published 2025“…</p>Results<p>Compared with HCs, dyslipidemic patients showed a significant reduction in gut microbial diversity. Specifically, the abundance of beneficial species—including Faecalibacterium prausnitzii, Bifidobacterium adolescentis, Bifidobacterium longum, Bifidobacterium bifidum, and Parabacteroides distasonis—was significantly decreased, while opportunistic pathogens such as Veillonella parvula, V. tobetsuensis, Streptococcus oralis, and Streptococcus mitis were notably enriched. …”
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19623
Data Sheet 1_Ribosomal protein L9 is a potential therapeutic target for B-ALL through the activation of the p53 signaling pathway.docx
Published 2025“…Enforced RPL9 knockdown (KD) led to decreased proliferation and increased apoptosis in B-ALL cells compared to the control group. …”
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19624
Data Sheet 7_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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19625
Renal function and risk of dementia: a Mendelian randomization study
Published 2024“…</p> <p>The findings indicate a significant correlation between each unit increase in cystatin C-based estimated glomerular filtration rate (eGFR-cys) levels was significantly associated with a reduction in the incidence of late-onset Alzheimer’s disease (LOAD) (IVW: OR = 0.35, 95% CI: 0.13–0.91, <i>p</i> = 0.031). …”
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19626
Data Sheet 1_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx
Published 2025“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”
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19627
Table 2_Integrative physiological, biochemical, and metabolomic analyses reveal complex drought and zinc stress tolerance in a novel Miscanthus hybrid.xlsx
Published 2025“…Fatty acid derivatives, nitrogen-containing compounds, hormone/signal-related compounds (jasmonate), and secondary metabolites (phenylpropanoids, N-containing compounds, and terpenes) showed significant (p < 0.05) abundance changes in response to D, Zn, and its combination D + Zn stress. …”
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19628
Data Sheet 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.zip
Published 2025“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”
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19629
Table 1_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx
Published 2025“…Fusobacterium, Prevotella 9, Parvimonas, and Holdemanella were significantly enriched in pre-surgical samples and declined after surgery (p < 0.01). …”
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19630
Data Sheet 1_An autonomous navigation method for orchard mobile robots based on octree 3D point cloud optimization.docx
Published 2025“…The lateral tracking error increased as the resolution of octree nodes decreased. At a resolution of 0.20 m, the maximum average lateral tracking error was 0.079 m, indicating strong path trackability. …”
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19631
Clinical and Imaging Characteristics of Posterior Scleritis in Children
Published 2025“…Retinal nerve fiber layer (RNFL) was thickened in all examined eyes (mean±SD 136.2 ± 28.4 µm) at presentation and it significantly decreased with treatment (109.8 ± 8.2 µm two months later). …”
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19632
Image 1_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.tif
Published 2025“…Significant heterogeneity was detected in the pooled analysis and meta-regression analysis suggested that participants’ age and the prevalence of diabetes significantly accounted for the heterogeneity.…”
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19633
Study area habitat quality LISA clustering map.
Published 2025“…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …”
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19634
Supplementary Material for: Emergency Renal Replacement Therapy with Manual Dialysis in a Patients with Acute Kidney Injury: First in Human Case Report
Published 2025“…Notably, portal vein pulsatility decreased from 38% to 31% following the procedure, indicating a reduction in fluid overload. …”
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19635
Image 1_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif
Published 2025“…Fusobacterium, Prevotella 9, Parvimonas, and Holdemanella were significantly enriched in pre-surgical samples and declined after surgery (p < 0.01). …”
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19636
Video 1_Safety and effectiveness of a new minimally invasive glaucoma surgery namely trabeculotome tunneling trabeculoplasty in primary open-angle glaucoma.mp4
Published 2025“…Postoperative IOP significantly decreased at all follow-up points except at 1 week (p < 0.05). …”
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19637
Data Sheet 3_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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19638
Data Sheet 1_Astragalus polysaccharide modulates the gut microbiota and metabolites of patients with major depressive disorder in an in vitro fermentation model: a pilot study.xlsx
Published 2025“…APS fermentation increased the abundance of Bifidobacterium and decreased the abundance of Lachnoclostridium (p < 0.05). …”
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19639
Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx
Published 2025“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”
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19640
Space-to-depth convolution.
Published 2025“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”