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20441
Figure 4 from OATP1B-type Transport Function Is a Determinant of Aromatase Inhibitor–Associated Arthralgia Susceptibility
Published 2025“…<p>OATP1B deficiency results in elevated AI plasma exposure and decreased liver accumulation. <b>A,</b> Pharmacokinetic profile of letrozole after a single oral dose of 10 mg/kg in wild-type and Oatp1a/1b<sup>(−/−)</sup> mice. …”
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20442
Table 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden...
Published 2025“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”
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20443
Evaluation standards of the CCD.
Published 2025“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”
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20444
Image 5_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif
Published 2025“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”
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20445
DataSheet1_Accumulation of coumaric acid is a key factor in tobacco continuous cropping obstacles.docx
Published 2024“…Introduction<p>Phenolic acids are believed to play a significant role in tobacco continuous cropping obstacles, but the strength and potential mechanisms of different phenolic acids remain unclear.…”
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20446
Image 6_Salt tolerance characterization and genome-wide association study of Gossypium barbadense accessions reveal salinity-adaptive variations.jpeg
Published 2025“…VIGS of GbXTH27 exacerbated salt-induced wilting phenotypes and significantly decreased antioxidant enzyme activities.…”
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20447
X-ray diffractometer and mineral composition.
Published 2025“…As the confining pressure increased, the ratio of tensile cracks in rock sample failure decreased, while the ratio of shear cracks increased. …”
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20448
Table 1_Contrasting interactions between photon spectra and temperature in cold-sensitive basil and cold-tolerant lettuce.docx
Published 2025“…The increased shoot expansion in lettuce decreased foliage coloration, but coloration was minimally altered in basil. …”
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20449
Image 1_Bacterial peptidoglycan levels have brain area, time of day, and sleep loss-induced fluctuations.jpg
Published 2025“…After 3 h of sleep disruption, PG levels increased in the somatosensory cortex, but decreased in brainstem, and hypothalamus. After 6 h of sleep disruption, PG increased in the brainstem and olfactory bulb compared to control levels. …”
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20450
Composition and Detailed Characterization of Amino Acids, Peptides, Proteins, Fatty Acids, and Minerals of Tuna Trimming Fish Meal
Published 2025“…Tuna processing byproducts hold significant nutritional value, though their quality can vary based on species, size, environment, and processing level. …”
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20451
Image 4_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif
Published 2025“…The age-standardized incidence rate (ASIR) experienced a decline of 1.07% from 1990 to 2021, while the age-standardized prevalence rate (ASPR) decreased by 0.95%. The incidence of EMT peaked among women aged 20–24 years, whereas mortality rates increased with advancing age. …”
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20452
Image 2_Bacterial peptidoglycan levels have brain area, time of day, and sleep loss-induced fluctuations.jpg
Published 2025“…After 3 h of sleep disruption, PG levels increased in the somatosensory cortex, but decreased in brainstem, and hypothalamus. After 6 h of sleep disruption, PG increased in the brainstem and olfactory bulb compared to control levels. …”
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20453
Image 1_Integrative stress management for global workforce: music-based and exercise intervention for overseas employees.jpeg
Published 2025“…</p>Results<p>The experimental group demonstrated significant stress reduction (GARS scores decreased from 3.59 ± 0.71 to 2.68 ± 0.57, p < 0.001), with effects sustained at 6 months (p < 0.05). …”
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20454
Oral L-Arginine Treatment Attenuates<i>Cryptococcus neoformans</i>Extrapulmonary Dissemination and Disease Progression
Published 2025“…Oral L-arginine supplementation significantly reduced fungal burdens in the brain and spleen, suggesting its effectiveness in controlling cryptococcal dissemination from the lungs. …”
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20455
QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells
Published 2024“…</p> <p>Quality-by-design methodology led to optimization and systematic formulation of coloaded protamine-coated PLGA nanoparticles.</p> <p>Protamine decreased the initial burst release of the formulations.…”
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20456
Optical Inline Interferometer for Enhanced Low-Field Detection via Electric-Field Induced Second Harmonic Generation
Published 2025“…Early LOE-FISH demonstrations relied on a delay line, resulting in decreased accuracy due to the higher sensitivity of the interferometer to environmental noise. …”
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20457
Video (Efficacy of uterine manipulator in total abdominal hysterectomy)
Published 2025“…The manipulator group experienced a decreased postoperative hematocrit drop of 15.9 g/dl (p <0.001). …”
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20458
Table 2_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.xlsx
Published 2025“…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …”
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20459
Sustained increase in the levels of pro-inflammatory cytokine and chemokine in the testis correlate with systemic inflammation.
Published 2025“…Pearson coefficient >0.6 was considered a significant correlation.</p>…”
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20460
Data_Sheet_14_Global burden of multiple sclerosis and its attributable risk factors, 1990–2019.PDF
Published 2024“…</p>Conclusion<p>Although the global age-standardized DALY rate of MS decreased between 1990 and 2019, MS continues to account for a considerable number of DALYs and prevalent cases. …”