Data Sheet 1_Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis.pdf حسب Leonie Ruths (20555753)

"…</p>Results<p>In the murine aging model, CD59-ko mice developed after 72 weeks more severe OA compared to C6-deficient and WT mice. mRNA analysis revealed that the expression of Cdkn1a, Cdkn2a, Tp53, Il1b, and Il6 was significantly increased in the cartilage of CD59-ko mice. …"

Data Sheet 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.pdf حسب Evan Fuini (21224939)

"…Treatment with psilocybin resulted in a significant dose-dependent increase in positive BOLD signal. …"

Table 2_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx حسب Sheng Zhou (66217)

"…Over the past 32 years, the average annual percentage change (AAPC) in the ASPR was statistically significant at −7.60% (t = −2.68, p < 0.05). Moreover, the annual percentage change (APC) in ASIR and ASPR showed the most significant decline from 2012 to 2015, with APCs of −70.47% (t = −3.01, p < 0.05) and − 66.55% (t = −14.94, p < 0.05), respectively.…"

Data Sheet 1_Exploring the relationship between occupational stress, physical activity and sedentary behavior using the Job-Demand-Control Model.docx حسب Maëlys Clinchamps (11080212)

"…Job strain was associated with increased sitting time and decreased physical activity. Further analysis revealed that being in a state of job strain significantly predicted sitting for more than 7 h per day. …"

Optimizing Irradiation Dose for <i>Drosophila melanogaster</i> Males to Enhance Heterospecific Sterile Insect Technique Against <i>Drosophila suzukii</i> حسب Flavia Cerasti (21075827)

"…<p dir="ltr">The spotted-wing drosophila (<i>Drosophila suzukii</i>), a highly invasive agricultural pest, poses significant challenges to fruit production worldwide. …"

Data Sheet 2_Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.pdf حسب Samira Rastgoo (15252703)

"…</p>Results<p>After the intervention, supplementation with D5N and D5 significantly downregulated p16, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) expression and decreased SA-β-gal activity compared to the D1 group. …"

Image 1_Genomic characterization and antibiotic susceptibility of biofilm-forming Borrelia afzelii and Borrelia garinii from patients with erythema migrans.tiff حسب Giorgia Fabrizio (19022288)

"…B. afzelii and B. garinii species exhibited biofilms, with biomass correlating significantly with eDNA production. MIC values were 0.25 μg/mL (amoxicillin, ceftriaxone), 0.125 μg/mL (azithromycin), and 0.5 μg/mL (doxycycline), with no significant interspecies differences. …"

Table 1_Genomic characterization and antibiotic susceptibility of biofilm-forming Borrelia afzelii and Borrelia garinii from patients with erythema migrans.pdf حسب Giorgia Fabrizio (19022288)

"…B. afzelii and B. garinii species exhibited biofilms, with biomass correlating significantly with eDNA production. MIC values were 0.25 μg/mL (amoxicillin, ceftriaxone), 0.125 μg/mL (azithromycin), and 0.5 μg/mL (doxycycline), with no significant interspecies differences. …"

Table 6_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx حسب Zemin Liu (224306)

"…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …"

Table 1_Impact of fasting and refeeding on immune markers, hepatic gene expression, and gut microbiota in geese: insights into metabolic regulation and gut-liver interactions.xlsx حسب Yi Liu (36759)

"…Additionally, 16S rRNA gene sequencing indicated that fasting increased the abundance of Bacteroidetes and Proteobacteria, while decreasing Firmicutes. Both alpha and beta diversity were significantly reduced during fasting. …"

Image 1_EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach.png حسب Eyad Talal Attar (22124251)

"…</p>Result<p>Examination of eventrelated potentials (ERPs) demonstrated that P300 amplitude showed significant growth when responding to oddball stimuli, which indicates increased attention allocation (p < 0.05). …"

Supplementary Material for: Association of Two Neonatal Encephalopathy Scores with Neurophysiology in Newborns with Suspected Hypoxic Ischemic Encephalopathy حسب figshare admin karger (2628495)

"…Conclusions: Both NE scores showed a significant correlation with neurophysiology, but NE scores have limitations. …"

Table 1_The impact of climate change on medicinal plants and natural products: A scoping review.pdf حسب Marce Inggritha Takubessi (22671905)

"…</p>Results<p>A total of 219 studies were included, showing a significant increase in publication after 2021. Most studies were conducted in Asia, especially in China and India, whereas Europe, Africa, and South America remain underrepresented. …"

Data Sheet 1_The six-year decomposition of coarse woody debris drives shifts in soil fungal communities in subtropical forests.docx حسب Nan Wang (21935)

"…We found that 6 years of CWD decomposition significantly increased soil organic carbon (SOC), dissolved organic carbon (DOC), and microbial biomass carbon (MBC) while reducing soil pH. …"

Table 2_Genomic characterization and antibiotic susceptibility of biofilm-forming Borrelia afzelii and Borrelia garinii from patients with erythema migrans.pdf حسب Giorgia Fabrizio (19022288)

"…B. afzelii and B. garinii species exhibited biofilms, with biomass correlating significantly with eDNA production. MIC values were 0.25 μg/mL (amoxicillin, ceftriaxone), 0.125 μg/mL (azithromycin), and 0.5 μg/mL (doxycycline), with no significant interspecies differences. …"

Table 1_Impact of prior exposures on biomarkers of blast during military tactical training.xlsx حسب Zhaoyu Wang (3059889)

"…Aβ40 and Aβ42 levels were significantly decreased in response to blast at the follow-up (~16 h) LLB exposure timepoint, concomitant with elevated expression of genes involved in amyloid-beta regulation and clearance in SMs with mTBI.…"

Supplementary file 1_Feasibility of repetitive transcranial magnetic stimulation on non-motor symptoms of spinocerebellar ataxia type 3: a secondary analysis of a randomized clinic... حسب Hua Wu (2707)

"…</p>Results<p>The results disclosed significant time effects for all the outcomes with post hoc comparisons showing differences of baseline and post-treatment evaluation, with decreases for PSQI, AIS, HARS, and HDRS as well as increase for MMSE and MoCA. …"

Table 1_Serum levels of interleukin-17, -18, -22, and -25 in patients with bullous pemphigoid before and after treatment.xlsx حسب Xinyi Hong (8181177)

"…</p>Results<p>The mean serum levels of IL-17, IL-18, IL-22, IL-25, and EOS percentage in BP patients were higher than those in healthy controls (all p < 0.001), and all of these levels decreased after treatment (all p < 0.001). There was no statistically significant difference in the titer of anti-BP180 or anti-BP230 antibodies before and after treatment. …"

Table 3_Effects of silver nanoparticles on the physiology, stress, and mineral uptake of banana cultivars in vitro and greenhouse.xlsx حسب Natalia Mendoza (22038296)

"…Rooting experiments revealed similar trends with high AgNP concentrations resulting in a decreasing root number and size. Greenhouse experiments on Gros Michel bananas, evaluating AgNP uptake through foliar and drench applications at 0, 25, 50, and 100 mg L^-1, monitored over a month, showed no statistically significant differences in growth parameters between treated plants and controls. …"

Table 3_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.xlsx حسب Zhuowen Hu (20431616)

"…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …"