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effects decrease » effects decreased (Expand Search), effects regress (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
effect regression » effects regression (Expand Search), forest regression (Expand Search), egger regression (Expand Search)
effects decrease » effects decreased (Expand Search), effects regress (Expand Search)
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21121
Image 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.png
Published 2025“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”
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21122
Table 1_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.pdf
Published 2025“…No statistically significant differences were observed in pulmonary mechanics between male mice with or without conditional loss of epithelial cell Bdnf, although treatment effects of IL-13 were noted. …”
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21123
Table 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.xlsx
Published 2025“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”
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21124
Image 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.jpeg
Published 2025“…</p>Results<p>By week 24, secukinumab treatment led to significant reductions in disease severity scores (QMG: 60.7%; MG-QOL15: 58.3%; MG-ADL: 64.1%) and AChR antibody levels (69.23%). …”
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21125
Data Sheet 2_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind...
Published 2025“…</p>Conclusion<p>HLTP exerts antidepressant effects in CUMS-induced rats by modulating the MGBA. …”
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21126
In sepsis-associated cardiotoxicity, remifentanil reduces oxidative stress, inflammation, and apoptosis to maintain mitochondrial biogenesis by inhibiting NFkB and Cas-3 immunoexpr...
Published 2025“…</p> <p>REMI exhibits significant cardioprotective effects in LPS-induced SIC by attenuating inflammation, oxidative stress, and apoptosis while preserving mitochondrial homeostasis.…”
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21127
Table 2_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.xlsx
Published 2025“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”
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21128
Genotoxic Mechanisms of Erythrophleum suaveolens Stem Bark Extracts and Fractions in MCF-7 Breast Cancer Cells via Mitochondrial and Non-Mitochondrial Pathways
Published 2025“…After 72 hours, ESSB-treated MCF-7 cells showed a significant (p < 0.05) increase in DNA fragmentation and comet tail DNA percentages (flavonoids induced a 1.21-fold increase in comet tail length). …”
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21129
Data Sheet 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.pdf
Published 2025“…</p>Results<p>By week 24, secukinumab treatment led to significant reductions in disease severity scores (QMG: 60.7%; MG-QOL15: 58.3%; MG-ADL: 64.1%) and AChR antibody levels (69.23%). …”
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21130
Data Sheet 1_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind...
Published 2025“…</p>Conclusion<p>HLTP exerts antidepressant effects in CUMS-induced rats by modulating the MGBA. …”
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21131
Data Sheet 1_The efficacy and safety of danuglipron and orforglipron in patients with type 2 diabetes and obesity: a systematic review and meta-analysis.docx
Published 2025“…Meta-analysis results demonstrated that danuglipron significantly decreased HbA1c (mean difference [MD]: −0.90; 95% CI: −1.06, −0.74), FPG (MD: −24.66; 95% CI: −30.45, −18.86) and weight (MD: −2.17; 95% CI: −3.10, −1.23) and improved FPI (MD: 2.94; 95% CI: 1.50, 4.38). …”
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21132
Data Sheet 1_Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3.docx
Published 2025“…The effect observed was dose-dependent. Mechanistically, anti-STAT3 mcDNA induces apoptosis and necrosis in treated cells, also revealing a certain dose-dependency, while also decreasing cell proliferation. …”
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21133
Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS
Published 2025“…</p> <p>Molecular hydrogen can effectively clear ROS caused by NEMP and has a significant role in protecting mitochondria from ROS. …”
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21134
Data Sheet 1_Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort.csv
Published 2025“…Purpose<p>Fasting is known to have beneficial effects on human physiology and health due to changes in gut microbiota and its associated metabolites. …”
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21135
Image 1_Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database.png
Published 2025“…It is often combined with radiotherapy and has cytotoxic effects on tumor cells. Although temozolomidee has a certain efficacy in the treatment of brain malignancies, its numerous adverse effects (AEs) suggest that its safety needs to be thoroughly evaluated.…”
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21136
Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf
Published 2025“…Background<p>Age-related ovarian dysfunction, characterized by declining follicular reserve and hormonal imbalance, poses a significant challenge in reproductive endocrinology, severely compromising fertility and quality of life. …”
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21137
Table_1_Correlation between ratio of fasting blood glucose to high density lipoprotein cholesterol in serum and non-alcoholic fatty liver disease in American adults: a population b...
Published 2025“…Background<p>Based on previous research, elevated fasting blood glucose (FBG) and decreased high-density lipoprotein cholesterol (HDL-C) levels are associated with non-alcoholic fatty liver disease (NAFLD). …”
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21138
Image 1_Association of hemoglobin variation and hospital mortality in patients with traumatic brain injury at high altitude.tif
Published 2025“…The threshold effects of ΔHb were explored through two-piecewise logistic regression models.…”
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21139
Data Sheet 1_The relationship between copper intake and chronic kidney disease/diabetic kidney disease: insights from NHANES data (2011-2018).xlsx
Published 2025“…This protective effect was observed consistently across all analyzed population subgroups. …”
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21140
Image7_Causal association between thyroid function and the risk of infertility: a Mendelian randomization study.jpeg
Published 2024“…</p>Results<p>The results indicated no causal effect of thyroid-stimulating hormone (TSH) and free tetraiodothyronine (fT4) on female and male infertility. …”