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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
levels decreased » levels increased (Expand Search)
event decrease » cement decreases (Expand Search), point decrease (Expand Search)
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20261
Effect of TRPML1 on inflammation in lymphedema mice.
Published 2024“…Compared with that of the SHAM group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes in the WT group was significantly increased. Compared with that in the WT group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes was significantly decreased in the TRPML1<sup>−/−</sup> group (*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001).…”
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20262
Image 9_Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy.tiff
Published 2025“…MAP2 expression was significantly decreased (p < 0.05) between 1.5–6.0 mm of the brain compared to Saline-Hypoxia and Naïve animals. …”
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20263
Aligned fibers cause higher <i>Plithotaxis</i> within monolayer.
Published 2025“…For all quintiles, <i>φ</i> distributions are significantly different between AF and RF (p<0.001 for <b>c-e</b>, p<0.05 for <b>f</b>). …”
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20264
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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20265
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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20266
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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20267
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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20268
Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries
Published 2025“…Heterologous T3SS expression significantly enhanced HN_xs01 adhesion and invasion capabilities in CF-203 cells. …”
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20269
ABR wave I and IV parameters in response to clicks.
Published 2025“…The P1-N1 amplitude at 90 dB SPL (<b>A</b>) was significantly reduced two days post-trauma compared to pre-trauma and stayed decreased three weeks post-trauma. …”
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20270
Data Sheet 1_Variation and spread of resistomes in swine manure, manure slurries, and long-term manure-fertilized soils.docx
Published 2025“…High-risk ARG abundance significantly increased from 404.7 in manure to 843.2 in slurries, with health-risk scores rising 1.88-fold during anaerobic digestion. …”
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20271
Flow Chart of the Study Steps.
Published 2025“…</p><p>Conclusion</p><p>The IP-GBL enhanced germane cognitive load and decreased the intrinsic and extrinsic cognitive load, which facilitated students’ learning. …”
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20272
Image 2_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif
Published 2025“…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”
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20273
Data Sheet 1_Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes.docx
Published 2025“…Background<p>Pregnancy significantly affects the maternal cardiovascular system, with physiological adaptations characterized by cardiac hypertrophy and increased capillarization. …”
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20274
Table 1_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx
Published 2025“…However, the change in age-standardized rates from 1990 to 2021 declined significantly. The association between the Socio-demographic Index (SDI) and the burden of amputations in 2021 was not linear. …”
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20275
Table 3_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx
Published 2025“…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…”
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20276
Integrating legumes into cropping systems enhances soil carbon and nitrogen content while reduces the soil carbon-to-nitrogen ratio: A global meta-analysis
Published 2025“…Moreover, SOC and STN increased when legumes replaced fallow or gramineous soil, whereas SCN significantly decreased only when legumes replaced gramineous systems. …”
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20277
Image 2_CT angiography-derived three-dimensional pulmonary vein topography is related to the outcome after cryoballoon ablation.tiff
Published 2025“…The number of occlusion attempts in the right inferior PV was significantly higher in the PVI failure group indicating a technical more complex balloon occlusion. …”
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20278
DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx
Published 2024“…Pharmacokinetic parameters such as AUC<sub>0-t</sub>, C<sub>max</sub> MRT, Vd, and half-life (t<sub>1/2</sub>) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar<sup>®</sup>). …”
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20279
Image 4_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti...
Published 2025“…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”
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20280
Image 1_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.pdf
Published 2024“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”