Microflow Liquid Chromatography Coupled to Multinozzle Electrospray Ionization for Improved Lipidomics Coverage of 3D Clear Cell Renal Cell Carcinoma by Sergey Girel (6887840)

“…With a runtime of 19 min, similar to our established analytical flow (AF/ESI) lipidomics platform, μF/mnESI produced a 16-fold median increase across 69 deuterated lipid standards. …”

<i>Oenocarpus bacaba</i> palm tree (A) and fruit (B). by Eudes Alves Simões-Neto (19697968)

“…Diagnosis criteria included positive peripheral blood smear (PBS), seroconversion of IgG, and a two-fold increase in IgG titer (laboratory criteria); and clinical findings, epidemiological exposure, and at least one positive IgG test (clinical-epidemiological criteria). …”

Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations by Han Liu (288039)

“…Furthermore, we identify that postglycosylation noncovalent polysaccharide chain transfer emerges as the decisive factor in cyclization, particularly for AM–degree of polymerization (DP) greater than 30 substrate complexes, where this noncovalent step (≥13.6 kcal/mol) dictates the rate of CA production. 57 variants with enhanced activity (up to a 2.3-fold increase) were engineered in our biochemical experiments by strategically modulating the chain transfer step. …”

Hdc loss in the MZ causes lamellocyte differentiation through cell-autonomous mechanisms. by Bayan Kharrat (19959505)

<i>hdc</i> depletion in progenitors triggers ROS production, but does not activate Foxo and insulin/mTOR. by Bayan Kharrat (19959505)

<i>hdc</i> silencing results in cellular stress in the hematopoietic niche. by Bayan Kharrat (19959505)

Cascade Nanozyme-Loaded Sprayable Hydrogels for Fibroblast Rejuvenation and Diabetic Wound Regeneration by Xinyi Zhang (36040)

“…In a bacterial-infected diabetic rat skin wound model, the zcgG group demonstrated substantially reduced inflammatory levels, a 68% decrease in AGEs, and a 1.9-fold increase in collagen deposition compared to blank controls. …”

Ydj1 acetylation alters interactions with client proteins. by Siddhi Omkar (12413434)

Ydj1 acetylation impacts multiple aspects of translation. by Siddhi Omkar (12413434)

Application of AIMEE to export normalized expression data for downstream analysis. by Jonah N. Cullen (5394503)

Single-phage therapy succeeds against phage resistance with a strong enough immune system. by Jacopo Marchi (7252499)

Downregulation of ATM1 affects iron-sulfur cluster proteins in <i>Toxoplasma</i> and iron levels in <i>Plasmodium</i>. by Deepti Shrivastava (17715780)

<i>Tg</i>ATM1-depleted <i>Toxoplasma</i> are functionally complemented through expression of the <i>Plasmodium</i> or yeast homolog. by Deepti Shrivastava (17715780)

Data Sheet 1_Perfusion process with tangential flow filtration for oncolytic VSV-GP production.docx by Orsolya Hamusics (21449015)

“…The study showed that several input parameters and their interactions have significant impact on the infectious titer. Increasing the seeding cell density significantly improved the infectious titer, allowing infection at up to 46.6 × 10⁶ cells mL^-1 without decrease in the cell-specific virus yield. …”

DataSheet1_RETRACTED: Ophthalmic Combination of SurR9-C84A and Trichostatin-A Targeting Molecular Pathogenesis of Alkali Burn.DOCX by Kislay Roy (3466256)

“…The cytokine array analysis revealed that NaOH induced expressions of IL-1α and MMP-9, which were found to be significantly downregulated (1.8 and 11.5 fold respectively) by the combinatorial treatment of SurR9-C84A and TSA.…”

Proteomics analysis comparing dsProsβ1- and dsmGFP-fed cabbage stem flea beetle adults. by Doga CEDDEN (12675286)

“…Proteins with fewer than three peptide counts were discarded. Statistical significance was set at adjusted P < 0.05, with significantly altered proteins defined by LogFold2 > 1 (increased) or LogFold2 < -1 (decreased). …”

Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx by Chen-xiao Liu (22750118)

“…TCF3 knockdown significantly attenuated these EMT changes and increased autophagy markers, as evidenced by decreased P62 levels (p < 0.01) and increased LC3-II/I ratio (p < 0.001) and Beclin-1 expression (p < 0.01). …”

DataSheet1_Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters.PDF by Safaa Yehia Eid (17768736)

“…In MCF-7/ADR and MDA-MB-231/ADR cells, COP (31 μM) enhanced DOX cytotoxicity with CI (0.77 and 0.75), RR (2.58 and 3.33), and IB suggesting synergism. COP significantly inhibits ABCT function in resistant BC cell lines, increases Rho123 accumulation, and decreases efflux more than VER; 2.1 and 1.2-fold, respectively. …”