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Cox proportional hazard ratios.
Published 2025“…<i>In vitro</i> results demonstrated that MBC-005 mediated its anti-tumorigenic effect through a p21-dependent mechanism via a novel molecular pathway, in which N-allyl noroxymorphone component of MBC-005 stimulated the opioid growth factor receptor to increase p21 expression. Intratumoral administration of MBC-005 increased survival 3.9-fold in mice and significantly decreased tumor volume 4-fold. …”
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Bioluminescent Doubling Time.
Published 2025“…<i>In vitro</i> results demonstrated that MBC-005 mediated its anti-tumorigenic effect through a p21-dependent mechanism via a novel molecular pathway, in which N-allyl noroxymorphone component of MBC-005 stimulated the opioid growth factor receptor to increase p21 expression. Intratumoral administration of MBC-005 increased survival 3.9-fold in mice and significantly decreased tumor volume 4-fold. …”
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Study Design.
Published 2025“…<i>In vitro</i> results demonstrated that MBC-005 mediated its anti-tumorigenic effect through a p21-dependent mechanism via a novel molecular pathway, in which N-allyl noroxymorphone component of MBC-005 stimulated the opioid growth factor receptor to increase p21 expression. Intratumoral administration of MBC-005 increased survival 3.9-fold in mice and significantly decreased tumor volume 4-fold. …”
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Table 4_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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Table 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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Table 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.docx
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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Table 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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Image 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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Supplementary file 1_Forced intensity-controlled endurance training on a small-animal treadmill machine inducing murine cardiac hypertrophy: insights and comparison to voluntary ru...
Published 2025“…After 8 and 12 weeks of training, the heart weight/tibia length ratio was significantly higher than the control. Cardiomyocyte (CM) cross-sectional areas were enlarged by 1.8-fold and shifted to the increased surface area upon training. …”
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Data Sheet 1_Eupalinolide A inhibits cancer progression and induces ferroptosis and apoptosis by targeting the AMPK/mTOR/SCD1 signalling in non-small cell lung cancer.docx
Published 2025“…It also promoted apoptosis (increasing the total apoptotic rate in A549 cells from 1.79% to 47.29% and that in H1299 cells from 4.66% to 44.43%) as well as ferroptosis (increasing ROS production by 2.46-fold in A549 cells and by 1.32-fold in H1299 cells). …”
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COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISEASE
Published 2024“…In some preferred embodiments, these have been designed using dehydroascorbic acid, ascorbic acid and amino acids as carriers that result in a significant increase in brain MMF concentration and mitochondrial biogenesis activity. …”
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Supplementary Tables S1 and S2
Published 2025“…However, both plasma-free and plasma-containing buffer induced small but significant increases in secretion of several cytokines over the sample collection period. …”
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Caffeine induces proteome-wide changes in a Rob-dependent manner.
Published 2025“…B* for all CPIs with non-zero Rob coefficients (n = 17), colored by regulator. (B) Caffeine increases MicF small RNA levels. Northern blot analysis confirming increased levels of small RNA MicF upon caffeine treatment (1 mM). …”