Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
gap decrease » gain decreased (Expand Search), mean decrease (Expand Search), step decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
gap decrease » gain decreased (Expand Search), mean decrease (Expand Search), step decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents
Published 2025“…Additionally, compound LP-65 demonstrated significant modulation of MEK and mTOR signaling activity in human glioma cells (D54) and human melanoma cells (A375), with a corresponding decrease in cellular proliferation and migration. …”
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Top 10 significant functional annotations of up-regulated DEGs.
Published 2025“…Functional annotations are ordered by decreasing significance, with color indicating significance according to the legend’s color scale, the ratio of genes on the horizontal axis, and DEG count represented by circle size.…”
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Top 10 significant functional annotations of down-regulated DEGs.
Published 2025“…Functional annotations are ordered by decreasing significance, with color indicating significance level based on the legend’s color scale, the ratio of genes on the horizontal axis, and DEG count represented by circle size.…”
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<i>Kif15</i> deficient mice exhibit both depressive and manic behaviors in adulthood.
Published 2025Subjects: -
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KIF15 interacts with PSD95 and affect its localization in neuronal cytoplasm neurons of the PFC.
Published 2025Subjects: -
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<i>Kif15</i> deficiency affects the expression of Gephyrin and GABRB1 in PFC and hippocampus.
Published 2025Subjects: -
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