In vivo antitumor activity of PHT-427 inhibitor-loaded polymeric nanoparticles in head and neck squamous cell carcinoma حسب Joaquín Yanes-Díaz (20539584)

"…PHT-427 encapsulation increased drug efficacy and safety, as demonstrated by decreased tumor volume, reduced PI3K/AKT/PDK1 pathway expression, and improved antitumor activity and necrosis induction in the mouse xenograft model. …"

Data Sheet 1_Pan-cancer analysis reveals TRA16 as a master regulator of human carcinogenesis.pdf حسب Yanyan Zhu (32035)

"…In liver cancer organoid models, TRA16 and its co-expressed genes were significantly upregulated. Intercellular communication analysis showed that TRA16-positive cells exhibited increased autocrine signaling and overall signaling activity. …"

Table 1_Effects of biochar on phosphorus fraction, phosphatase activity, and phosphorus-solubilizing bacterial abundance: a phosphorus-depleted biochar design.docx حسب Hongyi Qin (5943515)

"…Acid phosphatase activity was inhibited by PDB in upland soils (a peach orchard, a tea plantation, and a vegetable field). phoD-based sequencing indicated an increased relative abundance of dominant PSB genera in upland soils but a decreased abundance in paddy soils under PDB treatment. …"

Table 2_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.docx حسب Yujuan Wu (2249857)

"…</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …"

Comparison of 3D culture systems on mesenchymal stem cell longevity, regenerative potential, and secretome production حسب Jacob Hodge (2699521)

"…LIF, OCT4, IGF1) were significantly higher in Bio-Block ASCs. Secretome protein declined 35%, 47%, and 10% in 2D, spheroid, and Matrigel, respectively, but was preserved in Bio-Blocks. …"

S1PR2 inhibition reduces the levels of proinflammatory cytokines, including MCP1 in LPS- and S1P2-stimulated macrophages. حسب Aya Miyagawa-Hayashino (386487)

"…<i>S1PR2</i> siRNA treatment effectively silenced the corresponding target gene by 70%, as assessed by qPCR. (E) ELISA showing that supernatant levels of proinflammatory cytokines, including MCP1, TNF-α, and IL-6, were increased in macrophages stimulated with LPS. …"

DataSheet_1_RETRACTED: Ikzf2 Regulates the Development of ICOS+ Th Cells to Mediate Immune Response in the Spleen of S. japonicum-Infected C57BL/6 Mice.docx حسب Shihao Xie (8931347)

"…And then, the expression of Ikzf2 was verified to be significantly increased and mainly located in the nuclear of ICOS⁺ Th cells. …"

Using publicly available data and ML models to identify drug repurposing candidates in non-<i>NF2</i> schwannomatosis حسب Alexandra Scott (12883928)

"…After identifying significantly differentially expressed genes, we performed functional enrichment analyses in multiple gene set databases using enrichR.…"

Mean-based differential IC expression comparing human and canine cancer types and clusters. حسب Mikolaj Kocikowski (18520143)

"…<p>Genes that were found significant in both median- and mean-based analysis were marked in bold for denoting increased confidence. …"

DataSheet1_Metabolic engineering of hairy root cultures in Beta vulgaris for enhanced production of vanillin, 4-hydroxybenzoic acid, and vanillyl alcohol.docx حسب Zakir Husain (7320716)

"…The presence of the VpVAN gene in transgenic roots was confirmed using PCR analysis. …"

Table1_Metabolic engineering of hairy root cultures in Beta vulgaris for enhanced production of vanillin, 4-hydroxybenzoic acid, and vanillyl alcohol.DOCX حسب Zakir Husain (7320716)

"…The presence of the VpVAN gene in transgenic roots was confirmed using PCR analysis. …"

Table 2_Interactions between NAD+ metabolism and immune cell infiltration in ulcerative colitis: subtype identification and development of novel diagnostic models.xlsx حسب Linglin Tian (17953145)

"…Background<p>Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with increasing incidence worldwide. Growing evidence highlights the pivotal role of nicotinamide adenine dinucleotide (NAD+) metabolism in UC pathogenesis, prompting our investigation into the subtype-specific molecular underpinnings and diagnostic potential of NAD+ metabolism-related genes (NMRGs).…"

Image 1_Interactions between NAD+ metabolism and immune cell infiltration in ulcerative colitis: subtype identification and development of novel diagnostic models.tif حسب Linglin Tian (17953145)

"…Background<p>Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with increasing incidence worldwide. Growing evidence highlights the pivotal role of nicotinamide adenine dinucleotide (NAD+) metabolism in UC pathogenesis, prompting our investigation into the subtype-specific molecular underpinnings and diagnostic potential of NAD+ metabolism-related genes (NMRGs).…"

Image 2_Interactions between NAD+ metabolism and immune cell infiltration in ulcerative colitis: subtype identification and development of novel diagnostic models.tif حسب Linglin Tian (17953145)

"…Background<p>Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with increasing incidence worldwide. Growing evidence highlights the pivotal role of nicotinamide adenine dinucleotide (NAD+) metabolism in UC pathogenesis, prompting our investigation into the subtype-specific molecular underpinnings and diagnostic potential of NAD+ metabolism-related genes (NMRGs).…"

Table 1_Interactions between NAD+ metabolism and immune cell infiltration in ulcerative colitis: subtype identification and development of novel diagnostic models.xlsx حسب Linglin Tian (17953145)

"…Background<p>Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with increasing incidence worldwide. Growing evidence highlights the pivotal role of nicotinamide adenine dinucleotide (NAD+) metabolism in UC pathogenesis, prompting our investigation into the subtype-specific molecular underpinnings and diagnostic potential of NAD+ metabolism-related genes (NMRGs).…"

Image 1_Methyltransferase-like 3-mediated RNA N6-methyladenosine contributes to immune dysregulation: diagnostic biomarker and therapeutic target.jpeg حسب Deshuang Zhang (6004067)

"…<p>Methyltransferase-like 3 (METTL3) plays a crucial role in post-transcriptional gene regulation. Substantial evidence links METTL3 to various immune dysfunctions, such as the suppression of antiviral immunity during viral infections and the disruption of immune tolerance in conditions like autoimmune diseases, myeloid leukemia, skin cancers, and anticancer immunotherapy. …"

Data Sheet 1_Interplay between light and circadian rhythms in the regulation of photoreception and physiological processes in the stony coral Acropora digitifera.docx حسب Zongyan Shi (20506307)

"…Some genes tested by qPCR significantly fluctuated with light (pmca, sglt, ppp1r, egln, sod, and hsp70) and time (ca, pmca, sglt, ppp1r, hif1α, egln, sod, and sod). …"

Table 1_Interplay between light and circadian rhythms in the regulation of photoreception and physiological processes in the stony coral Acropora digitifera.xlsx حسب Zongyan Shi (20506307)

"…Some genes tested by qPCR significantly fluctuated with light (pmca, sglt, ppp1r, egln, sod, and hsp70) and time (ca, pmca, sglt, ppp1r, hif1α, egln, sod, and sod). …"

Data Sheet 1_Thymic stromal lymphopoietin modulates T cell response and improves cardiac repair post-myocardial infarction.pdf حسب Xuhong Wang (4783464)

"…RNA-seq analysis revealed significant downregulation of genes involved in T cell activation and TCR signaling in the infarcted heart of Crlf2^-/- mice compared with their WT counterparts.…"

Table 1_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.xlsx حسب Zhiyong Wang (313131)

"…Microbial diversity decreased as Se and other heavy metal concentrations increased. …"