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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), greatest decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), greatest decrease (Expand Search)
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21181
Table 2_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”
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21182
Table 4_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
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21183
Table 2_Building radiomics models based on ACR TI-RADS combining clinical features for discriminating benign and malignant thyroid nodules.docx
Published 2025“…At the statistically optimal threshold of 0.386, the unnecessary biopsy rate decreased from 46.97% to 22.05% in the training cohort and from 45.83% to 21.05% in the test cohort.…”
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21184
Image 1_HIV risk and influence factors among MSM who had sought sexual partners in core venues: a continuous sentinel surveillance in 2010–2022.png
Published 2024“…</p>Conclusion<p>Following the implementation of differentiated venue-based interventions, the risk of HIV among MSM who had sought sexual partners in core venues decreased to a level comparable to that of MSM who had not. …”
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21185
Table_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so...
Published 2024“…However, continuous cropping of this species has led to various obstacles, such as microbial disease and pest infestation, significantly affecting the production and development of valuable medicinal and food resources. …”
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21186
Table 2_Patient-needs-enhanced emergency nursing assessment framework accelerates time-critical care for non-traumatic chest pain.docx
Published 2025“…</p>Conclusions<p>Augmenting ENAF with a structured clinical-needs module significantly accelerates ECG acquisition, improves other process metrics and enhances nursing documentation while maintaining patient safety. …”
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21187
Image 2_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co...
Published 2025“…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …”
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21188
Table 5_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an...
Published 2025“…The most frequent grade 3–5 AEs in the PIBC group included anorexia (36.40%), decreased neutrophil count (16.25%), neutropenia (13.50%), reduced white blood cell count (12.12%), and febrile neutropenia (9.42%).…”
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21189
Table 6_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an...
Published 2025“…The most frequent grade 3–5 AEs in the PIBC group included anorexia (36.40%), decreased neutrophil count (16.25%), neutropenia (13.50%), reduced white blood cell count (12.12%), and febrile neutropenia (9.42%).…”
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21190
Inflammatory markers correlate with lymphocytes infiltrating and predict immunotherapy prognosis for esophageal cancer
Published 2024“…</p> <p><b>Results:</b> Decreased inflammation was found to be associated with increased CD3<sup>+</sup> and CD8<sup>+</sup> T-cell infiltration and a better prognosis. …”
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21191
Table 4_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”
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21192
Image 1_Augmentation of bone formation by sympathectomy in rats as evaluated by [99mTc]Tc-MDP.png
Published 2025“…SCGx rats exhibited significantly higher [<sup>99m</sup>Tc]Tc-MDP uptake and increased BMD, BV/TV, and BV in peri-fracture regions at all time points (p < 0.0001). …”
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21193
Table 5_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co...
Published 2025“…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …”
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21194
Caffeine induces proteome-wide changes in a Rob-dependent manner.
Published 2025“…The double-sided Fisher’s exact test p-value for enrichment of OMPs among significantly decreased proteins is shown. (D) Comparison of proteome changes between wild type and Δ<i>rob</i> upon caffeine treatment. …”
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21195
Image 1_Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a...
Published 2025“…Background<p>Although reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased. The accumulation of epicardial adipose tissue (EAT) may be associated with poorer STEMI prognosis and could serve as a potential prognostic marker. …”
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21196
Table 4_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”
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21197
The threshold effect analysis of the BRI on HGS.
Published 2025“…In the fully adjusted model, the negative correlation between BRI and MQI was (β= −0.08, 95% CI = −0.08, −0.07), while the positive correlation with HGS was (β= 0.3 8, 95% CI = 0.29, 0.46), indicating that for every unit increase in BRI, MQI decreases by 0.08 units and HGS increases by 0.38 units (P < 0.0001). …”
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21198
Table 2_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx
Published 2025“…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …”
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21199
Table 5_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”
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21200
Data Sheet 1_Capsaicin induces ferroptosis via suppression of SLC7A11 activity and upregulation of ACSL4 mediated by AMPK in tongue squamous cell carcinoma.zip
Published 2025“…</p>Results<p>CAP significantly suppressed the viability of HN6 and CAL27 cells. …”