Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greatest decrease » treatment decreased (Expand Search), greater increase (Expand Search)
genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), levels decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greatest decrease » treatment decreased (Expand Search), greater increase (Expand Search)
genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), levels decreased (Expand Search)
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Combination therapy exhibited apoptosis in Ba/F3 EML4-ALKmutant cell models.
Published 2025Subjects: -
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Ba/F3 EML4-ALK<sup>mutants</sup> exhibit variable dose-response to ABT-199 treatment.
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Molecular docking showed that ABT-199 can fit into active site of ALK<sup>Mutant</sup>.
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Amino acids interactions and binding energy describe that ABT-199 binds to ALK<sup>Mutant</sup>.
Published 2025Subjects: -
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Overexpression of miR-1247-3p promoted apoptosis and inhibited resistance in drug-resistant cells.
Published 2024Subjects: -
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ALK inhibitors (Positive control) and ABT199 (Proposed binding) in complex with the ALK active side.
Published 2025Subjects: -
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BCL2 antiapoptotic protein exhibits heterogeneous expression in Ba/F3 EML4-ALK<sup>mutants</sup>.
Published 2025Subjects: -
520