يعرض 19,721 - 19,740 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant ((genes decrease) OR (greatest decrease)) ))', وقت الاستعلام: 0.60s تنقيح النتائج
  1. 19721

    Cytochrome bd-II oxidase CyxA promotes the pathogenicity of <i>Klebsiella pneumoniae</i> by resisting oxidative stress حسب Xiao Xiao (99147)

    منشور في 2025
    "…Additionally, the expression levels of <i>cyxA</i> at 37°C and 41°C were significantly higher compared to 30°C, and the Δ<i>cyxA</i> strain exhibited significantly lower viable counts, elevated intracellular reactive oxygen species (ROS) levels, and decreased total antioxidant capacity (T-AOC) relative to WT at 37°C and 41°C. …"
  2. 19722

    ABR wave I and IV parameters in response to clicks. حسب Carolin Jüchter (17384611)

    منشور في 2025
    "…The P1-N1 amplitude at 90 dB SPL (<b>A</b>) was significantly reduced two days post-trauma compared to pre-trauma and stayed decreased three weeks post-trauma. …"
  3. 19723

    Flow Chart of the Study Steps. حسب Azam Hosseinpour (13434515)

    منشور في 2025
    "…</p><p>Conclusion</p><p>The IP-GBL enhanced germane cognitive load and decreased the intrinsic and extrinsic cognitive load, which facilitated students’ learning. …"
  4. 19724

    Image 2_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif حسب Houle Guo (21264647)

    منشور في 2025
    "…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …"
  5. 19725

    Image 1_Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome.jpeg حسب Mailén Rojo (10802556)

    منشور في 2025
    "…</p>Results<p>Our findings showed that patients with PCOS had decreased mtDNA content and increased oxidation damage. …"
  6. 19726

    Table 1_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx حسب Baixing Wei (21461966)

    منشور في 2025
    "…However, the change in age-standardized rates from 1990 to 2021 declined significantly. The association between the Socio-demographic Index (SDI) and the burden of amputations in 2021 was not linear. …"
  7. 19727

    Table 3_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx حسب Kaihao Lin (13016658)

    منشور في 2025
    "…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…"
  8. 19728

    Integrating legumes into cropping systems enhances soil carbon and nitrogen content while reduces the soil carbon-to-nitrogen ratio: A global meta-analysis حسب Zhiqiang Lu (20145192)

    منشور في 2025
    "…Moreover, SOC and STN increased when legumes replaced fallow or gramineous soil, whereas SCN significantly decreased only when legumes replaced gramineous systems. …"
  9. 19729

    Image 2_CT angiography-derived three-dimensional pulmonary vein topography is related to the outcome after cryoballoon ablation.tiff حسب Martin Saal (21267734)

    منشور في 2025
    "…The number of occlusion attempts in the right inferior PV was significantly higher in the PVI failure group indicating a technical more complex balloon occlusion. …"
  10. 19730

    DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx حسب Abdul Mateen (12055673)

    منشور في 2024
    "…Pharmacokinetic parameters such as AUC<sub>0-t</sub>, C<sub>max</sub> MRT, Vd, and half-life (t<sub>1/2</sub>) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar<sup>®</sup>). …"
  11. 19731

    Image 4_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti... حسب Junhyeok Choi (14078586)

    منشور في 2025
    "…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …"
  12. 19732

    Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx حسب Dehua Luo (22275916)

    منشور في 2025
    "…</p>Conclusion<p>Resveratrol significantly alleviates liver fibrosis in animal models via anti-inflammatory and antioxidant mechanisms. …"
  13. 19733

    Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function حسب Xialin Li (20449207)

    منشور في 2025
    "…Roxadustat also remarkably decreased the expression of KIM-1 and NGAL. Furthermore, roxadustat significantly abolished the expression of Bax and cleaved caspase 3, two apoptosis marker proteins. …"
  14. 19734

    Table 4_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.docx حسب Junzhe Chen (5729912)

    منشور في 2025
    "…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …"
  15. 19735

    Table 1_Evaluation of a multi-epitope vaccine PME for Pasteurella multocida in mouse model.docx حسب Rui Zhang (13940)

    منشور في 2025
    "…Furthermore, the pathological lung damages in the His-PME group and the pcDNA3.1-PME group were significantly alleviated, and the bacterial loads in lung tissues were significantly decreased. …"
  16. 19736

    Supplementary file 1_Application of multidimensional gait feature fusion algorithm in gait assessment for patients with knee osteoarthritis.docx حسب Yuzhe Tan (22274731)

    منشور في 2025
    "…The incorporation of multidimensional features significantly enhanced the performance of all classification models: under multidimensional feature input, RF, SVM, DT, and KNN achieved accuracies of 96.93%, 92.44%, 90.29%, and 88.98%, respectively—all significantly outperforming models using single‐dimensional features.…"
  17. 19737

    Image_3_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG حسب Bin Zhang (64682)

    منشور في 2025
    "…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
  18. 19738

    Supplementary Material for: Seizure Burden Before and After Lidocaine as Add-on Therapy in (a)EEG-Confirmed Neonatal Seizures حسب figshare admin karger (2628495)

    منشور في 2025
    "…After LDC administration, median TSB decreased significantly from 31 (interquartile range, IQR 16–68) to 0 minutes (IQR 0–0, p<0.01), and MSB from 10 (IQR 6–41) to 0 min/hour (IQR 0–0, p<0.01). …"
  19. 19739

    Image 1_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti... حسب Junhyeok Choi (14078586)

    منشور في 2025
    "…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …"
  20. 19740

    Image 5_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti... حسب Junhyeok Choi (14078586)

    منشور في 2025
    "…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …"