يعرض 21,141 - 21,160 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant ((genes decrease) OR (mean decrease)) ))', وقت الاستعلام: 0.57s تنقيح النتائج
  1. 21141

    Image 5_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... حسب Yun Xu (139234)

    منشور في 2025
    "…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …"
  2. 21142

    Table 1_Temporal trends and geographic disparities in thyroid cancer burden: a global analysis from 1990 to 2021.doc حسب Zuzhi Zhao (21724217)

    منشور في 2025
    "…</p>Conclusion<p>From 1990 to 2021, the global health burden of thyroid cancer increased significantly, with marked geographical disparities. …"
  3. 21143

    Table 7_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an... حسب Chao Song (379006)

    منشور في 2025
    "…The most frequent grade 3–5 AEs in the PIBC group included anorexia (36.40%), decreased neutrophil count (16.25%), neutropenia (13.50%), reduced white blood cell count (12.12%), and febrile neutropenia (9.42%).…"
  4. 21144

    Table 2_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx حسب Fan Lin (625737)

    منشور في 2025
    "…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …"
  5. 21145

    Maresin-1 alleviates sepsis-induced acute kidney injury by inhibiting ferroptosis via the Nrf2/HO-1/Gpx4 signaling pathway حسب Lili Tang (23345)

    منشور في 2025
    "…In the mouse model, MaR-1 administration decreased renal injury markers (BUN, SCr, NGAL) and ferroptosis-related indicators in kidney tissues. …"
  6. 21146

    Table 1_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx حسب Fan Lin (625737)

    منشور في 2025
    "…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …"
  7. 21147

    Supplementary Material for: Leveraging NLP for Psychiatric Phenotyping from Spanish EHR: Enabling the Investigation of Transdiagnostic Symptom Profiles at Scale حسب figshare admin karger (2628495)

    منشور في 2025
    "…The COMBINED algorithm improved overall recall, without significantly decreasing precision (F1 of 0.78 and 0.77 on HOMO and CSJDM, respectively). …"
  8. 21148

    Table1_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... حسب Hongbo Cheng (2848235)

    منشور في 2024
    "…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …"
  9. 21149

    Data Sheet 1_Adherence to a “MediterrAsian” diet is associated with weight loss-independent improvements in liver fat and lipid profile, but not glucoregulation or inflammation: se... حسب Yu Chung Chooi (18968382)

    منشور في 2025
    "…</p>Results<p>Body weight, total body fat, visceral and subcutaneous adipose tissues, and liver fat decreased significantly after the intervention, in tandem with improvements in markers of glucose and lipid metabolism and inflammation. …"
  10. 21150

    Table 1_Impact of dual residual risk of cholesterol and inflammation on adult male sex hormones: a cross-sectional study from NHANES.docx حسب Yang Zhou (65942)

    منشور في 2025
    "…In the presence of both risk factors (BR), TT decreased most significantly (β = -79.37, 95% CI [-112.74, -46.00], p < 0.0001), as did FT in the same subgroup (β = -1.00, 95% CI [-1.61, -0.40], p = 0.0012). …"
  11. 21151

    Table 8_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an... حسب Chao Song (379006)

    منشور في 2025
    "…The most frequent grade 3–5 AEs in the PIBC group included anorexia (36.40%), decreased neutrophil count (16.25%), neutropenia (13.50%), reduced white blood cell count (12.12%), and febrile neutropenia (9.42%).…"
  12. 21152

    Table 2_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an... حسب Chao Song (379006)

    منشور في 2025
    "…The most frequent grade 3–5 AEs in the PIBC group included anorexia (36.40%), decreased neutrophil count (16.25%), neutropenia (13.50%), reduced white blood cell count (12.12%), and febrile neutropenia (9.42%).…"
  13. 21153

    Data Sheet 2_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2... حسب Junhong Yang (7807046)

    منشور في 2025
    "…Finally, donors from outdoor blood collection sites (0.590%) and groups (1.073%) were at a significantly higher risk of syncope compared to those from indoor blood donation sites (0.438%) and individual donors (0.174%).…"
  14. 21154

    Data Sheet 1_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.... حسب Fan Lin (625737)

    منشور في 2025
    "…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …"
  15. 21155

    Supplementary Material for: Long-term outcomes and clinical factors associated with conventional therapy failure in intestinal Behçet’s disease: A retrospective cohort study in Jap... حسب figshare admin karger (2628495)

    منشور في 2025
    "…Concomitant glucocorticoid use significantly decreased from 12.7±11.7 mg/day at baseline to 2.4±2.5 mg/day at 1 year (p<0.001). …"
  16. 21156

    Image 1_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.tiff حسب Siying Wei (5990276)

    منشور في 2025
    "…However, the pandemic significantly slowed the decline in low- and low-middle SDI regions.…"
  17. 21157

    Table 1_Patient-needs-enhanced emergency nursing assessment framework accelerates time-critical care for non-traumatic chest pain.docx حسب Yan Sun (22436)

    منشور في 2025
    "…</p>Conclusions<p>Augmenting ENAF with a structured clinical-needs module significantly accelerates ECG acquisition, improves other process metrics and enhances nursing documentation while maintaining patient safety. …"
  18. 21158

    Efficient Dehydrogenation of Propane to Propene over PtIn Nanoclusters Encapsulated in Hollow-Structured Silicalite‑1 حسب Shiying Li (381113)

    منشور في 2024
    "…As a result, it displays a significantly higher specific activity for C<sub>3</sub>H<sub>6</sub> formation (0.37–0.59 s<sup>–1</sup>) than Pt@S1, Pt@S1–H, and other reported Pt-based catalysts. …"
  19. 21159

    Impact of Pilates training on gait performance in individuals with unilateral transtibial amputation حسب Janny Mirian Antonelli Tavares (22452771)

    منشور في 2025
    "…Walking speed increased significantly for SSWS (<i>p</i> < 0.001) and FWS (<i>p</i> = 0.002). …"
  20. 21160

    Image 2_Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a... حسب Zeyan Liu (3748747)

    منشور في 2025
    "…Background<p>Although reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased. The accumulation of epicardial adipose tissue (EAT) may be associated with poorer STEMI prognosis and could serve as a potential prognostic marker. …"