Showing 18,401 - 18,420 results of 21,342 for search '(( significant decrease decrease ) OR ( significant ((genes decrease) OR (mean decrease)) ))', query time: 0.80s Refine Results
  1. 18401

    Presentation_1_Multifaceted neuroprotective approach of Trolox in Alzheimer's disease mouse model: targeting Aβ pathology, neuroinflammation, oxidative stress, and synaptic dysfunc... by Muhammad Tahir (741682)

    Published 2024
    “…This research study is significant as it aims to assess the neuroprotective properties of vitamin E (VE) analog Trolox in an Aβ<sub>1 − 42</sub>-induced AD mouse model. …”
  2. 18402

    Data Sheet 1_Deep learning-based image reconstruction benefits diffusion tensor imaging for assessing severity of depression.docx by Yuanyuan Cui (276987)

    Published 2025
    “…</p>Results<p>Twenty-eight patients with mild-to-moderate depression and 24 with severe depression were included. No significant differences were observed between the two groups in terms of gender (p = 0.115), age (p = 0.603), or educational background (p = 0.148). …”
  3. 18403

    Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

    Published 2025
    “…Objective<p>The phase III ASTRUM-007 trial demonstrated significant clinical benefit in patients with PD-L1-positive esophageal squamous cell carcinoma (ESCC) treated with first-line serplulimab plus chemotherapy. …”
  4. 18404

    Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx by Naama Lax (20998004)

    Published 2025
    “…TMA event-free status was reached in 15 (63%) patients. Significant improvements were observed in platelet count (63%), lactate dehydrogenase levels (76% within the first week), hemoglobin (60%), and estimated glomerular filtration rate (79%); while CH-50 levels decreased. …”
  5. 18405

    Data Sheet 1_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

    Published 2025
    “…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”
  6. 18406

    Table1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.docx by Chao Bai (4428472)

    Published 2025
    “…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”
  7. 18407

    Table 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx by Cassidy Jones (22301638)

    Published 2025
    “…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”
  8. 18408

    <b>Species richness, composition and dominance of core and climate relicts of African Miombo woodlands</b> by Justice Muvengwi (22631075)

    Published 2025
    “…Significant differences in species composition were observed between sites, with the most pronounced dissimilarities between the core miombo woodland and Mozambique relict. …”
  9. 18409

    Table 2_Survival assessment in extremely preterm neonates in a middle-income setting.docx by Maria J. Rodriguez-Sibaja (17456689)

    Published 2025
    “…Notably, survival after extremely preterm birth was associated with significant morbidity.</p>…”
  10. 18410

    Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX by Shaoqun Huang (19810725)

    Published 2024
    “…</p>Conclusion<p>Our study explored a significant correlation between PHDI and biological aging, indicating that adherence to PHD may prevent biological aging.…”
  11. 18411

    Image 1_STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit.tiff by Mohammad Jodeiri Farshbaf (20466956)

    Published 2024
    “…Introduction<p>Diabetes is a metabolic disorder of glucose homeostasis that is a significant risk factor for neurodegenerative diseases, such as Alzheimer’s disease, as well as mood disorders, which often precede neurodegenerative conditions. …”
  12. 18412

    Table 1_Methodological approaches to survey complex ice cave environments - the case of Dobšiná (Slovakia).docx by Katarína Pukanská (20431835)

    Published 2024
    “…</p>Results<p>Between 2018 and 2023, the ice volume in certain sections of the cave decreased by up to 667 m³, with notable reductions in ice thickness ranging from 0.3 to 0.9 m in areas like the Small Hall and Collapsed Dome. …”
  13. 18413

    Image5_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

    Published 2024
    “…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
  14. 18414

    Image6_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

    Published 2024
    “…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
  15. 18415

    ORS and zinc coverage, by country, DHS data only. by Keith Beam (20700854)

    Published 2025
    “…Our findings demonstrate the long-term success of the SUZY project and provide insights into best practices for impactful zinc scale-up programs including significant pre-launch implementation research addressing key knowledge gaps and partnering with research organizations. …”
  16. 18416

    Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf by Junjie Jiang (7255706)

    Published 2024
    “…</p>Results<p>Analysis of data from the 2007–2018 NHANES survey revealed a significant negative association between CDAI and sleep disorders (OR = 0.854, 95% CI 0.821–0.888, P < 0.001). …”
  17. 18417

    Table 1_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.xlsx by Yue Song (162328)

    Published 2025
    “…</p>Results<p>Both the low-frequency electroacupuncture group and the high-frequency electroacupuncture group significantly reduced writhing scores, increased spleen index, decreased prostaglandin PGF2α and COX-2 levels, and increased prostaglandin PGE2 and β-EP levels to varying degrees.…”
  18. 18418

    Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i> by Meng-Ru Guo (21375491)

    Published 2025
    “…Research has shown that the absence of Cdc4, an F-box protein in <i>C. neoformans</i>, decreases virulence, yet the mechanisms by which Cdc4 affects these processes remain unclear. …”
  19. 18419

    Image 1_Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database.png by Yu Liu (6938)

    Published 2025
    “…Notable PTs included *petechiae* (ROR 9.87), *hemiparesis* (ROR 9.36), and *platelet count decreased* (ROR 8.61). Unexpected AEs, such as *pulmonary embolism* (ROR 4.96) and *Pneumocystis jirovecii pneumonia* (ROR 7.09), were identified. …”
  20. 18420

    Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf by Yaoyao Zhu (3487937)

    Published 2025
    “…Background<p>Age-related ovarian dysfunction, characterized by declining follicular reserve and hormonal imbalance, poses a significant challenge in reproductive endocrinology, severely compromising fertility and quality of life. …”