Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), greatest decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
genes decrease » teer decrease (Expand Search), sizes decrease (Expand Search), greatest decrease (Expand Search)
-
18401
Presentation_1_Multifaceted neuroprotective approach of Trolox in Alzheimer's disease mouse model: targeting Aβ pathology, neuroinflammation, oxidative stress, and synaptic dysfunc...
Published 2024“…This research study is significant as it aims to assess the neuroprotective properties of vitamin E (VE) analog Trolox in an Aβ<sub>1 − 42</sub>-induced AD mouse model. …”
-
18402
Data Sheet 1_Deep learning-based image reconstruction benefits diffusion tensor imaging for assessing severity of depression.docx
Published 2025“…</p>Results<p>Twenty-eight patients with mild-to-moderate depression and 24 with severe depression were included. No significant differences were observed between the two groups in terms of gender (p = 0.115), age (p = 0.603), or educational background (p = 0.148). …”
-
18403
Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx
Published 2025“…Objective<p>The phase III ASTRUM-007 trial demonstrated significant clinical benefit in patients with PD-L1-positive esophageal squamous cell carcinoma (ESCC) treated with first-line serplulimab plus chemotherapy. …”
-
18404
Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx
Published 2025“…TMA event-free status was reached in 15 (63%) patients. Significant improvements were observed in platelet count (63%), lactate dehydrogenase levels (76% within the first week), hemoglobin (60%), and estimated glomerular filtration rate (79%); while CH-50 levels decreased. …”
-
18405
Data Sheet 1_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf
Published 2025“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”
-
18406
Table1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.docx
Published 2025“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”
-
18407
Table 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx
Published 2025“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”
-
18408
<b>Species richness, composition and dominance of core and climate relicts of African Miombo woodlands</b>
Published 2025“…Significant differences in species composition were observed between sites, with the most pronounced dissimilarities between the core miombo woodland and Mozambique relict. …”
-
18409
Table 2_Survival assessment in extremely preterm neonates in a middle-income setting.docx
Published 2025“…Notably, survival after extremely preterm birth was associated with significant morbidity.</p>…”
-
18410
Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX
Published 2024“…</p>Conclusion<p>Our study explored a significant correlation between PHDI and biological aging, indicating that adherence to PHD may prevent biological aging.…”
-
18411
Image 1_STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit.tiff
Published 2024“…Introduction<p>Diabetes is a metabolic disorder of glucose homeostasis that is a significant risk factor for neurodegenerative diseases, such as Alzheimer’s disease, as well as mood disorders, which often precede neurodegenerative conditions. …”
-
18412
Table 1_Methodological approaches to survey complex ice cave environments - the case of Dobšiná (Slovakia).docx
Published 2024“…</p>Results<p>Between 2018 and 2023, the ice volume in certain sections of the cave decreased by up to 667 m³, with notable reductions in ice thickness ranging from 0.3 to 0.9 m in areas like the Small Hall and Collapsed Dome. …”
-
18413
Image5_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
-
18414
Image6_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
-
18415
ORS and zinc coverage, by country, DHS data only.
Published 2025“…Our findings demonstrate the long-term success of the SUZY project and provide insights into best practices for impactful zinc scale-up programs including significant pre-launch implementation research addressing key knowledge gaps and partnering with research organizations. …”
-
18416
Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf
Published 2024“…</p>Results<p>Analysis of data from the 2007–2018 NHANES survey revealed a significant negative association between CDAI and sleep disorders (OR = 0.854, 95% CI 0.821–0.888, P < 0.001). …”
-
18417
Table 1_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.xlsx
Published 2025“…</p>Results<p>Both the low-frequency electroacupuncture group and the high-frequency electroacupuncture group significantly reduced writhing scores, increased spleen index, decreased prostaglandin PGF2α and COX-2 levels, and increased prostaglandin PGE2 and β-EP levels to varying degrees.…”
-
18418
Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i>
Published 2025“…Research has shown that the absence of Cdc4, an F-box protein in <i>C. neoformans</i>, decreases virulence, yet the mechanisms by which Cdc4 affects these processes remain unclear. …”
-
18419
Image 1_Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database.png
Published 2025“…Notable PTs included *petechiae* (ROR 9.87), *hemiparesis* (ROR 9.36), and *platelet count decreased* (ROR 8.61). Unexpected AEs, such as *pulmonary embolism* (ROR 4.96) and *Pneumocystis jirovecii pneumonia* (ROR 7.09), were identified. …”
-
18420
Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf
Published 2025“…Background<p>Age-related ovarian dysfunction, characterized by declining follicular reserve and hormonal imbalance, poses a significant challenge in reproductive endocrinology, severely compromising fertility and quality of life. …”