Data Sheet 1_Promoting the development and approval of new traditional Chinese medicines in China: a pooled analysis of data from 2013 to 2024.docx by Xiaohong Long (20871797)

“…Although the review time for TCMs has significantly decreased after the reform, the overall development time has increased. …”

Table 1_Analysis and validation of biomarkers and immune cell infiltration profiles in unstable coronary atherosclerotic plaques using bioinformatics and machine learning.xlsx by Pengyue Jin (11657894)

“…Introduction<p>Decreased stability of coronary atherosclerotic plaques correlates with a heightened risk of acute coronary syndrome (ACS). …”

Table 2_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx by Fang Ding (222713)

“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”

Table 1_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx by Fang Ding (222713)

“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”

Table 1_Imaging PAM fluorometry reveals stable photosynthetic efficiency in multibiont symbioses on coral reefs.docx by Susanne Bähr (14525717)

“…However, F_v/F_m measurements near the crabs’ dwellings (<3 mm) showed significant increases (3–6%) in three colonies and significant decreases (4–12%) in two colonies. …”

Table 1_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.docx by Zhixun Bai (14021787)

“…</p>Conclusion<p>While global AVH burden is decreasing, significant disparities persist, warranting tailored interventions to enhance resource equity in high-SDI regions and strengthen healthcare infrastructure in low-SDI areas.…”

Data from: A dominance hypothesis argument for historical genetic gains and the fixation of heterosis in octoploid strawberry by Steven Knapp (8126379)

“…Conversely, heterosis was prevalent and significant among wide hybrids, especially for fruit count, a significant driver of genetic gains for fruit yield.  …”

Table 2_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.docx by Jiaoli Xu (20871584)

“…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…”

Table 1_Case Report: Generalized anxiety disorder and hypertension: a bidirectional loop unraveled by integrated management.docx by Junming Chen (3603422)

“…Multimodal management combining pharmacotherapy (escitalopram, tandospirone), transcranial magnetic stimulation (9 sessions), biofeedback (14 sessions), psychotherapy, and lifestyle interventions achieve: mean BP decreased significantly from 176/105 mmHg to 125/72 mmHg during hospitalization; significant anxiety reduction (HAMA = 3), mean BP stabilized at 131/77 mmHg with 50% reduction in antihypertensive dosages, normalization of elevated ACTH (99.9→normal pg/mL) and cortisol (18.7→normal μg/dL) and sustained improvement at 6-month follow-up.…”

Riboflavin inhibits growth and reduces virulence of <i>Cryptococcus neoformans in vitro</i> by membrane disruption and excessive accumulation of reactive oxygen species and exhibit... by Jian Huang (7250)

“…Finally, in mouse models of intranasal and intravenous infection, RF treatment significantly reduced the fungal burden in multiple organs, reduced lung and brain damage, and decreased the levels of plasma interferon (IFN)-γ, tumor necrosis factor (TNF)-α, and interleukin (IL)-4 in the early stage of infection. …”

qorA associated data by fengning chen (20930834)

“…Consequently, the Δ<i>qorA</i> strain exhibited decreased levels of antioxidant enzymes such as superoxide dismutase and reduced pigment production. …”

Table 1_Inoculation frequency and maize genotype influence plant growth-promoting effects of soil bacteria under low nitrogen conditions.xlsx by Lexie R. Foster (22235653)

“…In addition, our results showed a significant growth response to repeated inoculations with a beneficial bacterial isolate. …”

Table 5_Inoculation frequency and maize genotype influence plant growth-promoting effects of soil bacteria under low nitrogen conditions.xlsx by Lexie R. Foster (22235653)

“…In addition, our results showed a significant growth response to repeated inoculations with a beneficial bacterial isolate. …”

Data Sheet 1_Preclinical evidence for luteolin in ulcerative colitis: a meta-analysis and systematic review.docx by Yiyi Feng (12530035)

“…</p>Results<p>The meta-analysis revealed that LUT significantly ameliorated colon length, reduced the disease activity index, alleviated body weight loss, and decreased histological scores. …”

Data Sheet 1_Integrated computational and experimental identification of N-[(1H-1,2,4-triazol-3-yl)phenyl]-1-(1H-pyrazolo[3,4-b]pyridin-3-yl)methanamide as a potent and selective T... by Xinxin Ying (21507500)

“…Survival analysis revealed a significant correlation between elevated TIM-3 expression and decreased patient survival. …”

Table 3_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx by Fang Ding (222713)

“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”

Table 1_Detailed understanding of reduced geoeffectiveness of solar cycle 24 in association with geomagnetic storms.xlsx by R. Selvakumaran (21290378)

“…<p>Solar Cycle 24, the weakest in over a century, exhibited significant deviations from previous cycles, beginning with a prolonged minimum, weak polar fields, and asynchronous polar field reversal, leading to hemispheric asymmetry. …”

Table 2_Inoculation frequency and maize genotype influence plant growth-promoting effects of soil bacteria under low nitrogen conditions.xlsx by Lexie R. Foster (22235653)

“…In addition, our results showed a significant growth response to repeated inoculations with a beneficial bacterial isolate. …”

Data Sheet 1_Remarkable tumor response to Iruplinalkib in a 14-year-old girl with ALK-positive advanced metastatic non–small-cell lung cancer: a case report.pdf by Jiahao Wang (4710915)

“…Most metastatic lesions also showed significant regression. By six months, the pulmonary tumor had almost disappeared. …”

Supplemental data for "<b>Kidney cell response to acute cardiorenal and isolated kidney ischemia-reperfusion injury</b>" in Physiological Genomics by Kevin Burfeind (20421194)

“…In each dataset, we found that proximal tubule (PT) cells of the kidney undergo significant gene expression changes, with decreased expression of genes critically important for cell identity and function, indicative of dedifferentiation. …”