Data Sheet 1_Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease.zip by Xi Luo (361139)

“…Both PD models predicted reduced uptake of lysine and lactate, indicating coordinated metabolic processes between these components. In contrast, decreased methionine and urea uptake was exclusively predicted in the synaptic PD model, while decreased histidine and glyceric acid uptake was exclusive to the non-synaptic PD model. …”

Table 1_Multi-omics revealed that the postbiotic of hawthorn-probiotic alleviated constipation caused by loperamide in elderly mice.pdf by Yu Wei (365236)

“…Background<p>Constipation is a prevalent and recurrent gastrointestinal disorder causing significant discomfort. However, current treatments often prove ineffective. …”

Table 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.docx by Yu Qiao (462684)

“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”

Table 2_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Supplementary Material for: Off-label Use of Mycophenolate Mofetil in Immunoglobulin A Nephropathy: A Systematic Review and Meta-analysis by Feng L. (5056958)

“…No significant differences were detected in the incidence of ESRD (RR: 0.87, 95% CI: 0.38 to 2.03), or progression of chronic kidney disease (RR, 1.01; 95%CI, 0.22 to 4.57). …”

Data Sheet 1_Quantitative comparisons of pulmonary artery hemodynamics before and after Pulsta valve implantation in patients with Tetralogy of Fallot using computational fluid dyn... by Seung Min Baek (13994226)

“…After PPVI, the vorticity (RPA; 3.9–1.6/s, p = 0.008, LPA; 4.4–1.8/s, p = 0.011, MPA; 5.4–1.5/s, p = 0.008), and energy dissipation (104.1–38.1 mW, p = 0.028) decreased significantly, whereas changes in the Womersley and Reynolds numbers were not statistically significant. …”

Data from paper: <i> Twenty-year effect of sewage-sludge fertilization in a Mediterranean </i><i>grassland: Impact on species composition, functional groups and interrelation with... by Mercedes Valerio (22631942)

“…Our findings revealed significant alterations in community species composition lasting over two decades following fertilization. …”

Supplementary file 1_Efficacy and safety of indigo naturalis oil extract (Lindioil ointment) for the treatment of atopic dermatitis: a randomized, crossover, evaluator-blinded, con... by Chin-Yi Yang (8104340)

“…The proportion of Staphylococcus aureus species in AD lesions significantly decreased after both treatments, and was not different from that of non-lesion skin.…”

Image 1_The anti-depressive role of the Pei Yuan Kai Yu formula in cerebral small vessel disease based on gut microbiota.tif by Lixuan Yang (7331786)

“…</p>Results<p>In rats with CSVD and depression, PY significantly increased body weight; alleviated depression-like behaviors; and decreased the levels of inflammatory cytokines such as TNF-α, IL-1β, and IL-6 in both serum and hippocampus. …”

Data Sheet 1_Efficacy and safety of pseudolaric acid B against Echinococcus multilocularis in vitro and in a murine infection model.pdf by Zhuo-ma Dawa (20632718)

“…</p>Conclusion<p>PAB has a significant killing effect on E. multilocularis, suggesting that it is a potential candidate for the treatment of AE.…”

Supplemental Material For Coronary Microvascular Remodeling in Pressure-Overload RV by Ilham Essafri (21688937)

“…Notably, resistance was significantly higher in male SHAM mice compared to females at baseline, and decreased in males but not in females post-PAB. …”

Table 3_Burden of heart failure attributable to chronic kidney disease in older adults (1990–2021): an analysis from the global burden of disease study.docx by Wenli Liu (400084)

“…Background<p>Heart failure (HF) is a critical global health issue, with chronic kidney disease (CKD) as a significant contributing factor. Both primarily affect older adults, with prevalence rising substantially after age 60. …”

Table 4_Burden of heart failure attributable to chronic kidney disease in older adults (1990–2021): an analysis from the global burden of disease study.docx by Wenli Liu (400084)

“…Background<p>Heart failure (HF) is a critical global health issue, with chronic kidney disease (CKD) as a significant contributing factor. Both primarily affect older adults, with prevalence rising substantially after age 60. …”

Image3_Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin.J... by Fereshteh Sadeghian (19848177)

“…On the inner surface of the spermathecal tube, tension on the apical junctions is decreased by depletion of PLC-1 and NMY-1. Surprisingly, when basal contractility is increased through SPV-1 depletion, the tension on apical junctions also decreases, with the most significant effect on the junctions aligned in perpendicular to the axis of the spermatheca.…”

Image 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.tif by Yu Qiao (462684)

“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”

Image 2_Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers.tiff by Gaetano Zizzo (15853004)

“…Median length of stay (LOS) was 14 days, and mean ward-to-intensive care unit (ICU) transfer and in-hospital mortality rates were 11 and 26%, respectively; significant differences were observed over the years, with LOS peaks preceding mortality peaks by 1 year. …”

Loss of b-cell K_ATP reduces Ca²⁺ sensitivity of insulin secretion and <i>Trpm5</i> expression by Nathaniel W. York (20410828)

“…</a><a href="" target="_blank">Glibenclamide pellet-implanted <i>Trpm5</i> KO mice also exhibited significant glucose intolerance. However, this was not as severe as in WT animals, which suggests that decreased expression of <i>Trpm5</i> may play a small role in the disruption of insulin secretion with K_ATP loss.…”

Image4_Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin.J... by Fereshteh Sadeghian (19848177)

“…On the inner surface of the spermathecal tube, tension on the apical junctions is decreased by depletion of PLC-1 and NMY-1. Surprisingly, when basal contractility is increased through SPV-1 depletion, the tension on apical junctions also decreases, with the most significant effect on the junctions aligned in perpendicular to the axis of the spermatheca.…”

Video3_Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin.A... by Fereshteh Sadeghian (19848177)

“…On the inner surface of the spermathecal tube, tension on the apical junctions is decreased by depletion of PLC-1 and NMY-1. Surprisingly, when basal contractility is increased through SPV-1 depletion, the tension on apical junctions also decreases, with the most significant effect on the junctions aligned in perpendicular to the axis of the spermatheca.…”

Video 1_Quantitative comparisons of pulmonary artery hemodynamics before and after Pulsta valve implantation in patients with Tetralogy of Fallot using computational fluid dynamics... by Seung Min Baek (13994226)

“…After PPVI, the vorticity (RPA; 3.9–1.6/s, p = 0.008, LPA; 4.4–1.8/s, p = 0.011, MPA; 5.4–1.5/s, p = 0.008), and energy dissipation (104.1–38.1 mW, p = 0.028) decreased significantly, whereas changes in the Womersley and Reynolds numbers were not statistically significant. …”