Supplementary file 2_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx by Jinming Cao (7837883)

“…Nationally, the burden of the disease in 2021 is particularly significant in countries such as Mauritius and Italy. …”

Supplementary file 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.docx by Xiaofang Guo (385478)

“…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …”

Data Sheet 1_Effects of simulated litter inputs on ecological niches and interspecific connectivity of alpine meadow plants.xlsx by Weishan Lin (20756891)

“…Introduction<p>Plant litter enters the soil as the main nutrient for alpine meadow ecosystems, and the amount of litter input has a significant effect on alpine meadow plant diversity, ecological niches, and interspecific connectivity.…”

Table3_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx by Mingming Hou (11341656)

“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”

<b><i>Assessment of Diseases’ Prevalence, Nutrition and Associated Factors in a Conflict-Affected Region: A Study in Leepa Valley, Azad Jammu and Kashmir, Pakistan</i></b> by Zoha Khan (19100603)

“…Moreover, 76.3% reported decreased employment opportunities in Leepa Valley due to the ongoing border conflicts. …”

Table 1_Biofilm formation and role of other pathogenic factors in the virulence of Staphylococcus epidermidis clinical isolates.docx by María Coronada Fernández-Calderón (21993110)

“…<p>Medical device-associated infections represent a significant healthcare challenge, as sterilization of the biomaterial often necessitates device removal. …”

Table 1_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx by Guilin Ren (18720749)

“…</p>Results<p>HFD induced biochemical abnormalities and liver injury, which were significantly reversed by Pac, as evidenced by decreased plasma levels of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase), TG (Triglyceride), and TC (Total cholesterol), and reduced hepatic TG and TC levels. …”

Image 2_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif by Xiaochuan Yu (2410861)

“…The age-standardized incidence rate (ASIR) experienced a decline of 1.07% from 1990 to 2021, while the age-standardized prevalence rate (ASPR) decreased by 0.95%. The incidence of EMT peaked among women aged 20–24 years, whereas mortality rates increased with advancing age. …”

Table 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.docx by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”

Data_Sheet_1_Global burden of multiple sclerosis and its attributable risk factors, 1990–2019.PDF by Saeid Safiri (3713035)

“…</p>Conclusion<p>Although the global age-standardized DALY rate of MS decreased between 1990 and 2019, MS continues to account for a considerable number of DALYs and prevalent cases. …”

Table 1_In vivo profiling of the PE/PPE proteins of Mycobacterium tuberculosis reveals diverse contributions to virulence.xlsx by Benjamin Koleske (11581641)

“…In all, 27 of the 87 mutants showed significant reductions in percent population prevalence in the lung over 3 weeks. …”

Evaluation indicators system of ER. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Image 1_Salt tolerance characterization and genome-wide association study of Gossypium barbadense accessions reveal salinity-adaptive variations.jpeg by Huazu Li (22228792)

“…VIGS of GbXTH27 exacerbated salt-induced wilting phenotypes and significantly decreased antioxidant enzyme activities.…”

The statistics of residential land price. by Wenqi Li (137889)

“…<div><p>Exploring the spatial structure of residential land prices within metropolitan areas is crucial for identifying regional development disparities. It holds significant practical value for guiding the rational allocation of resources, optimizing land use efficiency, and promoting collaborative development across the metropolitan region. …”

Table 7_Transcriptome and metabolome profiling reveal the chlorogenic acid as a resistance substance for rice against the white-backed planthopper Sogatella furcifera (Horváth).xls... by Wenqi Xie (5903936)

“…Exogenous application of CGA to TN1 enhanced its tolerance and antixenosis to WBPH, significantly decreasing WBPH’s survival and mean dry weight. …”

Table 4_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”

Data Sheet 1_Mechanism of salidroside promoting testosterone secretion induced by H2O2 in TM3 Leydig cells based on metabolomics and network pharmacology.zip by Zixu Wang (6297470)

“…The study investigated the oxidative damage in TM3 cells induced by H₂O₂ and demonstrated that salidroside significantly decreased the levels of ROS and MDA, while increasing the levels of testosterone, SOD, GSH. …”

Evaluation indicators system of DI. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Supplementary file 1_Monitoring the dual-season hydrological dynamics of the Pong reservoir in Himachal Pradesh, India.docx by Rajesh Sarda (13162317)

“…Analysis based on MNDWI indices reveals significant seasonal fluctuations in water coverage, with 36.18 km² of the reservoir exhibiting seasonal characteristics. …”

Supplementary file 1_Meta-analysis of Xiaoyao formula as an adjuvant therapy for treating postpartum depression.docx by Jing Liu (38537)

“…Additionally, XYF as an adjuvant therapy also significantly decreased Hamilton Depression Scale scores (standard mean difference [SMD] -1.69; 95% CI -2.37 to -1.01).…”