Supplementary file 1_Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.docx حسب Jinghuai Ni (21023477)

"…Objectives<p>Scorpion and Centipede (SC) is an ancient formula of traditional Chinese medicine that is commonly utilized in a range of disorders, and it has been shown to have pharmacological effects on postmenopausal osteoporosis (PMOP). …"

DataSheet1_Lipocalin-2 drives neuropsychiatric and cutaneous disease in MRL/lpr mice.docx حسب Sayra J. Garcia (19748644)

"…</p>Results<p>In this study, we found that LCN2 deficiency significantly attenuates neuropsychiatric and cutaneous disease in MRL/lpr lupus prone mice, likely by decreasing local infiltration of immune cells into the brain and skin and reducing astrocyte activation in the hippocampus. …"

Data Sheet 5_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf حسب Qi Dong (119569)

"…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …"

Table 2_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf حسب Qiao Ma (136536)

"…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …"

Table 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx حسب Yihan Liu (2258221)

"…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …"

Data Sheet 1_Metabolic adaptation to acute metabolic stress via PFKFB3 upregulation in rodent beta cells.doc حسب Koki Chiba (5413028)

"…Introduction<p>Pancreatic beta cells undergo metabolic remodeling in response to metabolic overload, but the functional significance of this remains unclear. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) is a glycolytic regulator that may play a role in beta cell adaptation under acute metabolic stress. …"

Image 1_Knockdown ATG5 gene by rAAV9 alleviates doxorubicin-induced cardiac toxicity by inhibiting GATA4 autophagic degradation.jpeg حسب Ai-Li Xu (20622440)

"…<p>Doxorubicin (DOX) is a prevalent chemotherapeutic drug for treating several malignancies. …"

Data Sheet 2_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.docx حسب Qi Dong (119569)

"…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …"

Data Sheet 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx حسب Yihan Liu (2258221)

"…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …"

Table1_Predicting the solubility of CO2 and N2 in ionic liquids based on COSMO-RS and machine learning.xlsx حسب Hongling Qin (5557505)

"…To further improve the performance of COSMO-RS, two options were used, i.e., the polynomial expression to correct the COSMO-RS results and the combination of COSMO-RS and machine learning algorithms (eXtreme Gradient Boosting, XGBoost) to develop a hybrid model. The results show that the COSMO-RS with correction can significantly improve the prediction of CO₂ solubility, and the corresponding average absolute relative deviation (AARD) is decreased from 43.4% to 11.9%. …"

Comparison of 3D culture systems on mesenchymal stem cell longevity, regenerative potential, and secretome production حسب Jacob Hodge (2699521)

"…LIF, OCT4, IGF1) were significantly higher in Bio-Block ASCs. Secretome protein declined 35%, 47%, and 10% in 2D, spheroid, and Matrigel, respectively, but was preserved in Bio-Blocks. …"

Effect of hypoxia on hepatocyte injury in NAFLD model mice. حسب Meiyuan Tian (22311505)

"…<p>(A) Analysis of mitochondrial membrane potential in hepatocytes in vivo. …"

Data Sheet 1_The C-terminal regions of the GLP-1 and GIP receptors are not the key determinants of their differential arrestin recruitment but modulate the rate of receptor endocyt... حسب Bashaier Al-Zaid (20930291)

"…The reciprocal substitution significantly (P < 0.005) decreased internalization rate.…"

Data Sheet 1_Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.pdf حسب Alex Ramos (16267028)

"…Background<p>Preeclampsia (PE) is a pregnancy complication characterized by hypertension, proteinuria, endothelial dysfunction, and complement dysregulation. …"

Impact of Pilates training on gait performance in individuals with unilateral transtibial amputation حسب Janny Mirian Antonelli Tavares (22452771)

"…<p>To evaluate the effects of a 3-month Pilates training program on spatiotemporal gait parameters in unilateral transtibial amputees (TTA).…"

CONSORT Flowchart of Participants. حسب Mitsuyo Nonaka (20827083)

"…<div><p>While adults with intellectual disabilities have a high prevalence of obesity, few weight loss interventions exist for them, and those that do exist target people with mild or moderate disabilities. …"

Table 1_The association between dietary creatine intake and cancer in U.S. adults: insights from NHANES 2007–2018.docx حسب Junhui Jiang (592060)

"…RCS analysis revealed a linear, positive correlation between age and cancer risk. …"

Table1_Gut microbiota and metabolomics unveil the mechanisms of Lomatogonium rotatum in ameliorating visceral fat and serum lipids in high-fat diet-induced obese mice.XLSX حسب Xiaoping Ji (531042)

"…<p>Lomatogonium rotatum (LR) is a folk medicinal herb traditionally used as a lipid-lowering and anti-obesity agent; but its pharmacological mechanism is unclear. …"

Data Sheet 1_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.pdf حسب Yan Fan (575147)

"…Background<p>IGFBP5 is a differentially expressed gene (DEG) between M1 and M2 macrophages. …"

Data Sheet 1_Chrysin sensitizes glioblastoma cells and spheroids to temozolomide treatment by reducing EMT and stemness phenotypes, as well as targeting multidrug resistance protei... حسب Yunus Aksüt (22163416)

"…In 3D spheroid models, co-treatments significantly impaired growth and viability.</p>Conclusion<p>These findings suggest that CHR may be a promising adjuvant to TMZ therapy, providing novel insights into overcoming chemoresistance in GB treatment.…"