Table3_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studies.x... by Lucie Hejnova (19676323)

“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”

Data Sheet 1_Cytokine-driven glycosphingolipid metabolism modulates endoplasmic reticulum calcium homeostasis in primary human renal mesangial cells.pdf by Mariia Stefanenko (16987420)

“…The increase in cytosolic Ca²⁺ was attributed to a decrease in endoplasmic reticulum (ER) Ca²⁺ store capacity. …”

Datasheet2_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi... by Lucie Hejnova (19676323)

“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”

Datasheet1_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi... by Lucie Hejnova (19676323)

“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”

Immune cell subsets and cytokine levels in peripheral blood between healthy donors and triple-negative breast cancer (TNBC) patients and in patients before and after the first phas... by Nicole Chicken (19806183)

“…This study showed an increase in the percentage of CD14⁺ monocytes and CD56^high NK cells and a decrease in CD19⁺ B-cells after first-phase chemotherapy, while no significant differences in cell percentages were seen between healthy donors and treatment-naïve patient groups. …”

POm shows pronounced response disparity to active and passive whisker stimuli. by Anton Sumser (21021061)

“…Rate increase: 4/11 neurons, rate decrease: 1/11 neurons (light gray), non-significant: 6/11 neurons. …”

Ydj1 acetylation alters interactions with client proteins. by Siddhi Omkar (12413434)

“…Interactors are colored according to change in interaction as follows: green (significant increase), red (significant decrease), or purple (no significant change) 6KQ/6KR. …”

S1 Raw data - by Yongle Du (3992198)

“…By integrating metabonomics with network pharmacology, we identified core targets of ZJP against myopia and constructed a compound-gene-disease-metabolite network. The expressions of LPCAT1 and CHRNA7 were found to decrease in the LIM group but increase with ZJP treatment, whereas NOS2 expression showed the opposite pattern.…”

Management of asthma exacerbations in pediatric emergency departments across the United States by Melisa S. Tanverdi (17948353)

“…Most (74.9%) encounters resulted in ED discharge with a downward trend of visits for exacerbations per 1,000 ED visits of −9.77, 95% CI [–9.99,-9.54], increase in disposition to intensive care unit of 2.01 [1.87,2.41] and decrease in home/other of −3.77 [–4.34,–3.20]. …”

Data Sheet 1_Dietary supplementation with proanthocyanidins and rutin alleviates the symptoms of type 2 diabetes mice and regulates gut microbiota.docx by Yue Gao (263086)

“…Importantly, several core microbes, particularly a series of probiotics, such as Akkermansia, Lactococcus, Odoribacter, Faecalibaculum, and Roseburia were identified, which were significantly correlated with the changes in BW and FBG.…”

Costs of treating serious adverse effects of drugs used for treatment of obesity: comparison of selected European countries by Branislava Raičević (20102929)

“…Healthcare utilization and costs of treating ADRs to antiobesity drugs vary significantly among European countries. These differences should be considered when creating inputs for cost-effectiveness and budget impact models to decrease their uncertainty.…”

Table 1_Southward shift of winter wheat area intensifies regional water scarcity in the Beijing-Tianjin-Hebei region.docx by Qi Yan (287702)

“…Our findings reveal three distinct phases in wheat planting area changes, characterized by initial increase, subsequent decrease, and eventual stabilization. The southward shift in spatial distribution, evidenced by a 58-km migration of the planting centroids, led to significant water resource disparities. …”

Variation in defensive traits against herbivores of native and invasive populations of <i>Carpobrotus edulis</i> by Jonatan Rodríguez (9852590)

“…This release from natural enemies might decrease the investment in expensive defense mechanisms (i.e., digestibility reducers) against the attack of specialist enemies, whilst increasing the investment in defenses (i.e., cheap toxins) and tolerance against the attack of generalist herbivores, as exposed by the Shifting Defense Hypothesis (SDH). …”

Data Sheet 1_Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function.docx by Amy K. Stark (20470996)

“…</p>Results<p>Prostaglandin E2 (PGE2) stimulation of retinal endothelial monolayers caused a decrease in barrier permeability in electric cell-substrate impedance sensing (ECIS) assays and dextran flux assays. …”

Primer sequences for target genes. by Yongle Du (3992198)

“…By integrating metabonomics with network pharmacology, we identified core targets of ZJP against myopia and constructed a compound-gene-disease-metabolite network. The expressions of LPCAT1 and CHRNA7 were found to decrease in the LIM group but increase with ZJP treatment, whereas NOS2 expression showed the opposite pattern.…”

Data Sheet 1_Prevalence of fungal colonization among patients with psoriasis in difficult-to-treat areas: impact of apremilast on mycotic burden and clinical outcomes.pdf by Elena Campione (8906858)

“…Finally, improvements in clinical scores i.e., PASI, NAPSI, DLQI, itch VAS, PAIN VAS, scPGA and sPGA-G and biochemical serum profile, as well as a significant decrease in serum IL-17A, TGF-β 1 and IL-10 levels (from 8.51 to 4.16 pg/mL; from 66.10 to 48.70 ng/mL and from 20.05 to 14 pg/mL, respectively) were observed in all patients.…”

Nonadjacent dependency learning in Swiss toddlers (Bodard et al., 2025) by Julie Bodard (21715023)

“…However, at 27 months, we observed a significant decrease in gaze duration for ungrammatical test trials between the first and the second blocks, together with a tendency to look longer at grammatical stimuli in the second block, a pattern of results that, if confirmed in future studies, might indicate the start of novel NAD learning.…”

Data Sheet 1_Impact of primary production and net ecosystem metabolism on carbon and nutrient cycling at the land-sea interface.docx by Louise C. V. Rewrie (21016172)

“…Despite the high nutrient concentrations and estimated GPP rates, the system was in near trophic balance, with seasonally averaged NEM estimates of -2 ± 49 mg C m^-2 d^-1 and -149 ± 41 mg C m^-2 d^-1. A significant finding is that a seasonal decrease in dissolved inorganic carbon of 125 – 160 µmol kg^-1 from May to September, and in total alkalinity of 116 – 128 µmol kg^-1 from December to August, was likely driven by the concurrent and significant seasonal uptake of inorganic carbon by primary producers in the upper estuary and upstream regions. …”

Table 1_Quantifying the effect of air pollution and temperature on hospitalization costs for chronic lower respiratory diseases.docx by Huanhuan Jia (2546878)

“…With respect to temperature, the hospitalization costs of people aged 60 and above increased by 8.70% on low-temperature days, and the exposure response ratio from lag day 0 to lag day 5 showed a statistically significant gradual decrease. Additionally, on lag days 5 and 11, the hospitalization costs of female patients with CLRDs increased by 3.35 and 3.92%, respectively.…”

Table 2_Global burden and trends of norovirus-associated diseases from 1990 to 2021 an observational trend study.xlsx by MengLan Zhu (20517257)

“…Background<p>Norovirus remains a significant viral cause of waterborne and foodborne gastroenteritis outbreaks and epidemics worldwide. …”