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17501
Supplementary Material for: Effect of gonadotropin dose reduction during COH on progesterone levels and embryo outcomes in women undergoing IVF/ICSI-ET with GnRH-A protocol
Published 2025“…The proportion of patients with P ≥ 1.5 ng/ml was significantly lower in the gonadotropin dose reduction group compared to the control group (22.7% vs. 29.9%, P=0.003).Multivariable logistic regression indicated that dose reduction decreased the risk of progesterone elevation [OR=0.535, 95% CI: 0.404-0.709]. …”
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17502
Data Sheet 2_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx
Published 2025“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. …”
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17503
Table 1_Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning.x...
Published 2025“…Recovery analysis showed significantly reduced adaptive immune cells at 1 month, with partial recovery by 3 and 6 months. …”
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17504
Accelerated drug action with 3D HD-MEA compared to planar HD-MEA.
Published 2025“…<p>To test the effectiveness of drug perfusion, TTX was applied to acute cerebellar slices. A) Examples of electrical activity maps showing the distribution of active electrodes before (<i><i>top</i></i>) and after TTX application (<i><i>bottom</i></i>) in a slice placed on a 3D chip (color scale bar: 0-300 µV). …”
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17505
Supplementary file 2_Effects of Lactiplantibacillus plantarum DSM 33464 in children with elevated blood lead levels: a randomized, double-blind, placebo-controlled study.docx
Published 2025“…Introduction<p>Approximately one-third of the world’s children have elevated blood lead levels (BLLs), which may lead to often-irreversible decreased intelligence, behavioral difficulties, and learning problems. …”
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17506
Table 2_SRC is a potential target of Arctigenin in treating triple-negative breast cancer: based on machine learning algorithms, molecular modeling and in Vitro test.xlsx
Published 2025“…Western blotting indicated that AG significantly reduced the levels of Bcl-2, caspase-3, and caspase-9, as well as decreased SRC, p-PI3K-p85, p-AKT1, p-MEK1/2, and p-ERK1/2 expression in TNBC cells in a concentration dependent manner.…”
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17507
Table 3_SRC is a potential target of Arctigenin in treating triple-negative breast cancer: based on machine learning algorithms, molecular modeling and in Vitro test.docx
Published 2025“…Western blotting indicated that AG significantly reduced the levels of Bcl-2, caspase-3, and caspase-9, as well as decreased SRC, p-PI3K-p85, p-AKT1, p-MEK1/2, and p-ERK1/2 expression in TNBC cells in a concentration dependent manner.…”
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17508
Additional file 2 of Evobrutinib mitigates neuroinflammation after ischemic stroke by targeting M1 microglial polarization via the TLR4/Myd88/NF-κB pathway
Published 2025“…Statistical analysis revealed no significant differences in CD80+ expression between MCAO and Evobrutinib group while the expression of MHCII+ microglia decreased in Evobrutinib group compared to MCAO. …”
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17509
Data Sheet 2_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx
Published 2025“…</p>Methods<p>This prospective, open-label, randomized, controlled, single-center pilot study (BroVID study; EudraCT 2021–003237-11) was conducted in adult outpatients with mild COVID-19, cough, and ≥1 additional symptom. Patients were randomly assigned to the thyme-ivy syrup group, which received three 5.4 mL doses of oral thyme-ivy syrup per day for 14 days, or a control group (no medication) in a 2:1 ratio. …”
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17510
Data Sheet 1_MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.zip
Published 2025“…Background<p>Major Facilitator Superfamily Domain-containing 12 (MFSD12) has emerged as a critical transmembrane protein with increasingly recognized roles in various cancers. …”
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17511
DataSheet2_Fibroblasts modulate epithelial cell behavior within the proliferative niche and differentiated cell zone within a human colonic crypt model.xlsx
Published 2024“…The crypts possessed a basal stem cell niche populated with proliferative cells and a differentiated, nondividing cell zone at the luminal crypt end. …”
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17512
Distance from the optimal direction for different levels of reward probabilities.
Published 2025“…As the conflict increases, accuracy decreases and RTs show a lower average decrease after plasticity B) Cosine distances with respect to the RT (minimization), Accuracy (maximization) and Reward rate (maximization) vectors for the three reward probabilities. …”
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17513
Data Sheet 1_The association of healthy eating index score and n-3 fatty acid intake with cardiovascular diseases incidence and lipid biomarkers in Alberta’s tomorrow project cohor...
Published 2025“…However, higher relative intake (i.e., n-3 FA as proportion of energy) increased the risk of developing CVD [HR = 1.42 (95%CI 1.1–1.84), p = 0.006] in males. …”
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17514
Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology...
Published 2025“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
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17515
Supplementary Material for: Treatment of plaque psoriasis with guselkumab reduces systemic inflammatory burden as measured by neutrophil/lymphocyte ratio, platelet/lymphocyte ratio...
Published 2025“…In VOYAGE I, NLR (p=0.011), PLR (p=0.015) and MLR (p=0.004) decreased significantly following 16 weeks of guselkumab treatment vs. placebo. …”
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17516
Oligonucleotides used for vector clone.
Published 2024“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”
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17517
Information of chemicals used in this study.
Published 2024“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”
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17518
Oligonucleotides used for amplification.
Published 2024“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”
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17519
Data Sheet 1_Crosstalk between MSC-extracellular vesicles and Olea europaea leaf extract in encapsulated liposomal hydrogel: attenuation of neuroinflammation and brain neurotransmi...
Published 2025“…The findings of this study demonstrated that the neuroprotective effect of the combined Lipo-OLE-Hydrogel and MSC-Exo treatment was associated with a significant reduction in oxidative stress, as evidenced by the restoration of total antioxidant capacity and the marked decrease in oxidative biomarkers, including reactive oxygen species (ROS), H<sub>2</sub>O<sub>2</sub>, and malondialdehyde (MDA). …”
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17520
Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden...
Published 2025“…</p>Results<p>The study included 100 inpatients with a mean age of 78.1 years (SD = 6.78). The total number of medications decreased by 6.6% (from 1,144 to 1,068; p < 0.001), with an acceptance rate of 59.2%. …”