Candidate genes by Genome-wide CRISPR Screen. by Mingyi Xu (5575871)

“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”

Data Sheet 1_Prevalence of kidney stones based on metabolic health and weight criteria: reports from the national health and nutrition examination survey 2007-2018 data analysis.pd... by Xijie Ding (21583937)

“…Physical activity was associated with a decreased risk of kidney stones, particularly among individuals with MUO. …”

Table_1_Effect of diet low in omega-6 polyunsaturated fatty acids on the global burden of cardiovascular diseases and future trends: evidence from the Global Burden of Disease 2021... by Qingsong Mao (19522438)

“…The most significant effects were seen in individuals aged 75 and older, with a higher disease burden noted in males. …”

Data Sheet 1_Multi-compartment immune cell profiling highlights the prognostic relevance of CD127+ CD8+ T cells for patients with high-grade serous ovarian cancer.docx by Rebecca Rothe (10292883)

“…In general, a high immune cell infiltration has a favorable effect on OC patients’ outcomes. …”

Table 3_Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.docx by Alexander Owusu Boakye (13716966)

“…Among females, those with the T allele of ACE2 rs2285666 had a 38% decreased susceptibility to SARS-CoV-2 infection under the dominant [adjusted odds ratio (aOR) = 0.62; 95%CI = 0.45–0.85, P = 0.003] and heterozygous advantage models (aOR = 0.62; 95%CI = 0.45–0.86, P = 0.004), after adjusting for confounders, but not thee recessive model (aOR = 0.41; 95%CI = 0.03–5.22, P = 0.490). …”

Table 2_Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.docx by Alexander Owusu Boakye (13716966)

“…Among females, those with the T allele of ACE2 rs2285666 had a 38% decreased susceptibility to SARS-CoV-2 infection under the dominant [adjusted odds ratio (aOR) = 0.62; 95%CI = 0.45–0.85, P = 0.003] and heterozygous advantage models (aOR = 0.62; 95%CI = 0.45–0.86, P = 0.004), after adjusting for confounders, but not thee recessive model (aOR = 0.41; 95%CI = 0.03–5.22, P = 0.490). …”

DataSheet1_Pressure-tolerant survival mechanism of Schizophyllum commune 20R-7-F01 isolated from deep sediments 2 kilometers below the seafloor.csv by Mengshi Zhao (20157978)

“…In this study, we investigated Schizophyllum commune 20R-7-F01 isolated from coal-bearing sediments at a depth of 2 km below the seafloor. By assessing the cell viability, biomass, and cell wall thickness changes of strain 20-7-1 under different HHP conditions, we observed that, compared to 0.1 MPa, strain 20-7-1 exhibited slower growth rates and decreased cell viability at 15 MPa and 35 MPa, yet demonstrated significant pressure tolerance. …”

Image 1_Genome-wide identification of GDPD gene family in foxtail millet (Setaria italica L.) and functional characterization of SiGDPD14 under low phosphorus stress.png by Chaomin Meng (21496829)

“…Under low phosphorus stress, the expression levels of SiGDPD3 and SiGDPD14 significantly increased, while SiGDPD1, SiGDPD5, SiGDPD6, and SiGDPD11 showed significant decreases.To identify the function of SiGDPD14, an over-expressed transgenic Arabidopsis was generated. …”

Data Sheet 2_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... by Ettore Silvagni (9576002)

“…Exposure to JAKis was not associated with a significantly increased risk of CVEs [adjusted hazard ratio (HR): 0.92; 95% CI: 0.64–1.32], MACEs (adjusted HR: 0.71; 95% CI: 0.37–1.33), or TEs (adjusted HR: 1.53; 95% CI: 0.65–3.65) compared to TNFis. …”

Data Sheet 1_Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.d... by Carol Costa Encarnação (21412730)

“…</p>Results<p>Our findings revealed that OB EVs induced significant phosphorylation of STAT3, a key signaling molecule in cancer progression, and promoted increased cell migration, dependent on fatty acid oxidation (FAO). …”

Supplementary file 1_Global burden of HIV, syphilis, and HBV infection among women of childbearing age and children under five: based on the Global Burden of Diseases Study 2021.do... by Jia Lian (9469818)

“…Both the ASPR of HBV infection among WCBA and the ASIR among children under five declined significantly from 1990 to 2021, with average annual percentage changes of −1.25% and −4.14%, respectively. …”

DataSheet1_Shenshuaikang enema restores the intestinal barrier and microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-κB pathway.docx by Yan Ye (549400)

“…It has become a significant public health problem, posing a threat to human health worldwide. …”

Data Sheet 1_Beta-amyloid influences the content and trafficking of beta-amyloid precursor protein via Na,K-ATPase-Src kinase positive feedback loop.pdf by Irina Y. Petrushanko (5696714)

“…Furthermore, 100 nM CTS ouabain, a specific Na,K-ATPase ligand, significantly decreased Aβ′s impact on APP and Src kinase activation. …”

Data Sheet 1_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip by Ziqi Tang (10904159)

“…Conversely, O₃-related mortality exhibited a significant upward trend. At reference concentrations of 0 and 60 μg/m³, all-cause mortality increased by 24.25% (365,084 cases) and 79.70% (372,724 cases), respectively. …”

DataSheet1_Effects of inulin-type oligosaccharides (JSO) from Cichorium intybus L. on behavioral deficits induced by chronic restraint stress in mice and associated molecular alter... by Caihong Yao (15344128)

“…Histological and molecular analyses revealed that JSO treatment attenuated neuronal loss in the hippocampus (Hip) and medial prefrontal cortex (mPFC) and reduced the expression of inflammatory markers such as Iba-1 and GFAP in these regions. JSO significantly downregulated the mRNA and protein expression of pro-inflammatory factors (IL-1β, TNF-α, IL-6) while increasing anti-inflammatory markers (IL-10, TGF-β) (P< 0.05). …”

Data Sheet 1_Stand structure influences understory plant diversity through soil factors: three afforestation types of Masson’s pine in the upper Yangtze River, China.docx by Yongqi Xiang (12548293)

“…In terms of stand structure, MCLMF significantly increased the opening degree (O), mingling index (M), and competition index (CI), while MLMF decreased CI but increased M. …”

In Vivo, In Vitro, and In Silico Assessment of Anticancer Activity of the New Pincer-Type Pt(II) Complexes by Danijela Nićiforović (21958700)

“…Two new complexes [Pt­(L1)­Cl]Cl (<b>Pt1</b>) and [Pt­(L2)­Cl]­Cl (<b>Pt2</b>), (L1 = <i>N</i>²,<i>N</i>⁶-bis­(5-methylthiazol-2-yl)­pyridine-2,6-dicarboxamide and L2 = <i>N</i>²,<i>N</i>⁶-di­(benzo­[<i>d</i>]­thiazol-2-yl)­pyridine-2,6-dicarboxamide), were synthesized and characterized. …”

In Vivo, In Vitro, and In Silico Assessment of Anticancer Activity of the New Pincer-Type Pt(II) Complexes by Danijela Nićiforović (21958700)

“…Two new complexes [Pt­(L1)­Cl]Cl (<b>Pt1</b>) and [Pt­(L2)­Cl]­Cl (<b>Pt2</b>), (L1 = <i>N</i>²,<i>N</i>⁶-bis­(5-methylthiazol-2-yl)­pyridine-2,6-dicarboxamide and L2 = <i>N</i>²,<i>N</i>⁶-di­(benzo­[<i>d</i>]­thiazol-2-yl)­pyridine-2,6-dicarboxamide), were synthesized and characterized. …”

Image 1_Oral supplementation with Lactobacillus fermentum MC018 improves intestinal health, immune response, and growth performance of Zi geese infected with Escherichia coli XH197... by Yang Li (7082)

“…Introduction<p>Escherichia coli infection causes severe diarrhea, decreases growth performance, and increases mortality of poultry, which imposes a significant economic burden on the poultry industry and severely limits its growth.…”

Supplementary file 1_Negative associations between macronutrient quality index and lung cancer incidence and mortality: results from the prostate, lung, colorectal, and ovarian can... by Dazhan Feng (22286776)

“…Our results demonstrate a distinct, statistically significant inverse association between a higher MQI and both a reduced incidence (HR Q4 vs. …”