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18981
Azole drugs have differential efficacy in varied models of immunosuppression in larval zebrafish hosts
Published 2025“…Repeated daily imaging of whole live larvae treated with posaconazole demonstrates that posaconazole treatment can prevent germination of <i>A. fumigatus</i> spores inside infected hosts but that this drug does not significantly combat fungal hyphal growth post-germination.…”
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18982
CCDC66 localizes to the axoneme and regulates primary cilium stability but not cilia formation in IMCD3 cells.
Published 2025“…Ciliary vesicle ectocytosis or fragments were categorized based on the size of the released EVs, vesicle < 500 nm and fragment > 500 nm, and plotted as a bar plot. (<i>p</i> values of Welch’s <i>t</i> test, **<i>p</i> = 0.0074, ***<i>p</i> = 0.0007, ns = not significant). …”
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18983
CRISPR/Cas9-mediated editing of barley lipoxygenase genes promotes grain fatty acid accumulation and storability
Published 2025“…Notably, the total LOX activity in mature grains decreased by 36–42% in <i>loxC1</i> mutants and by 94% in <i>loxAloxC1</i> mutants, with no significant change observed in <i>loxB</i> mutants. …”
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18984
DataSheet2_Mineral nutrition for Cannabis sativa in the vegetative stage using response surface analysis.docx
Published 2024“…N × K interaction had a significant effect on leaf mass and stem mass. …”
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18985
CLAD_sequence_files
Published 2025“…</b>BALF metabolomes varied by underlying disease state, with AATD LT recipients being particularly distinctive (PERMANOVA, <i>p</i>= 0.001, F= 3.91). We also found a significant association with the final CLAD severity score (RF variance explained = 11.08%, PERMANOVA, <i>p</i>=0.001), especially those with underlying CF. …”
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18986
Osseointegration of an innovative functionally gradient biomimetic scaffold based on Voronoi-Tessellation for the design of orthopaedic implants
Published 2025“…<p>The geometry and pore size of porous structures have a significant impact on osseointegration in orthopaedic implant design. …”
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18987
Ventromedial PFC pattern-separates cue-task associations.
Published 2025“…(C) The significant pattern separation effect (i.e., the negative coefficient, indicated by the red dashed line) compared with a null distribution obtained by randomly shuffling the transition point 5,000 times.…”
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18988
Genetic insights into the interaction between chronic hepatitis B virus infection and metabolic syndrome
Published 2025“…Further colocalization and mediation analyses were performed for traits with significant causal relationships. The effect of HBV on lipid metabolism was validated by <i>in vitro</i> assays. …”
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18989
Supplemental file for the manuscript "Unconventional myosin VI is involved in regulation of muscle energy metabolism" by Dominika Wojton, Dorota Dymkowska, Damian Matysniak, Malgor...
Published 2025“…To explore its role in mitochondrial function and muscle metabolism, we used MVI knockout mice (<i>Snell's waltzer</i>, <i>SV</i>, MVI-KO) and their heterozygous littermates. …”
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18990
Evaluation of Chemical Potentials, Bulk Modulus and Volume Expansion Ratio of Li-Si Alloys with Variety of Li Concentrations Using First-Principles Calculations (Supporting Informa...
Published 2025“…The analysis shows that, the chemical potential becomes as high as +75 kJ mol<sup>−2</sup> when the composition ratio approaches the maximum one of 4.4 in Li–Si alloys. This is consistent with the fact that no Li–Si alloys with a composition beyond this ratio have been observed. …”
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18991
Supplementary Material for: Association of Two Neonatal Encephalopathy Scores with Neurophysiology in Newborns with Suspected Hypoxic Ischemic Encephalopathy
Published 2025“…Results: There was a significant association between both NE scores and aEEG/cEEG (p<0.001), with higher scores in newborns with more abnormal aEEG background patterns. …”
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18992
Data - developmental timing.
Published 2025“…<div><p>Toys are us (Trus) is the <i>Drosophila melanogaster</i> ortholog of mammalian Programmed Cell Death 2-Like (PDCD2L), a protein that has been implicated in ribosome biogenesis, cell cycle regulation, and oncogenesis. …”
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18993
Figure 3 from Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRP...
Published 2025“…<b>A,</b> Significant change in mitochondrial fragmentation is indicated by the brackets. *, <i>P</i> < 0.01; **, <i>P</i> < 0.005; ***, <i>P</i> < 0.0001 (using the Mann–Whitney <i>U</i> test, calculated in Prism 9.0). …”
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18994
Post-traumatic stress disorder in German youth: representative claims data pre- vs. intra-COVID-19-pandemic
Published 2025“…</p> <p><b>Results:</b> PTSD prevalence decreased intra-COVID (girls: 0.8%, <i>n</i> = 2.595 vs. 0.6%, <i>n</i> = 1.965; OR = 0.77 [0.73, 0.82]; boys: 0.6%, <i>n</i> = 2.066 vs. 0.4%, <i>n</i> = 1.547; OR = 0.76 [0.71, 0.81]). …”
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18995
Supplementary Material for: Real-life nationwide outcomes of bronchoscopic lung volume reduction with endobronchial valves in severe COPD
Published 2024“…Results: Following BLVR, a significant increase in FEV1, similar to the improvements reported in randomized controlled trials was observed. …”
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18996
Using insects for sustainable waste management of superabundant animals
Published 2025“…However, sterilization did not have a significant effect neither in the body weight nor in the lifespan of adults. …”
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18997
Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease
Published 2025“…</p> <p>We included 25 PD patients with a mean age of 65.7 ± 9.0 y (F/M = 9/16). The comparative analyses between medication-off and -on states revealed that the MDS-UPDRS-3 scores decreased significantly during the medication-on states (<i>p</i> < 0.001, d = 1.09). …”
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18998
Low-speed Rear-end Collisions: Kinematic and Clinical Responses (Video, MRI findings, EMG/NCS results)
Published 2025“…Pain questionnaires were administered immediately after the test and one week later.</i></p><p dir="ltr"><b><i>Results</i></b><i>: Impact velocity, offset percentage, and collision type significantly influenced acceleration forces and NIC values, with passenger vehicle collisions generating higher forces than bumper car collisions. …”
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18999
CircFNDC3B inhibits vascular smooth muscle cells proliferation in abdominal aortic aneurysms by targeting the miR-1270/PDCD10 axis
Published 2024“…Additionally, RNA immunoprecipitation (RIP), dual-luciferase reporter assay, Western blotting, and rescue experiments were utilized to elucidate the molecular mechanism of circFNDC3B. <i>Results.</i> Our findings revealed a significant upregulation of circFNDC3B expression in AAA clinical specimens compared to normal tissues. …”
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19000
Dynamic changes in mRNA stability.
Published 2025“…Line plots showing relative mRNA levels after ActD treatment. Half-life values (<i><i>t</i></i><sub><i>1/2</i></sub>) for each LPS treated samples were estimated using a linear regression (see Methods). …”