Oxazolidinone susceptibility testing of <i>MAB_2885</i> mutants, complemented strains, and <i>MAB_2302-MAB_2303</i> overexpression strain. by Huiyun Zhang (1383231)

Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction by Zhihui Liu (95891)

“…Given that mitochondria are the primary source of reactive oxygen species (ROS), we assessed cellular ROS and mitochondrial superoxide levels by flow cytometry and found a significant increase. GOT1 knockdown increased the sensitivity of cells to cisplatin and decreased the volume of tumors in vivo. …”

A summary of state-of-the-art in the literature. by Mohammadreza Namdar (22439057)

“…<div><p>Software bug report classification is one of the most significant processes in software development for determining the nature and severity of faults based on their causes and effects. …”

Table 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

Feature importance generated by a logistic regression classifier to differentiate benign and malignant myxoid tumors. by Joshua M. Lawrenz (20623563)

Results for Case Study-I. by Nouman Qamar (21511939)

The study flowchart. by Yuko Noda (20396439)

“…There was no significant difference in non-HDL-C levels in the long-term groups or at 1 year. …”

Image1_Overexpression of TaPIP1A enhances drought and salt stress tolerance in Arabidopsis: cross-species conservation and molecular dynamics.jpeg by Jie Han (128758)

“…In TaPIP1A knockout wheat strains, there was a significant decrease in stress tolerance, whereas Arabidopsis plants overexpressing TaPIP1A exhibited marked improvements in survival under similar stress conditions. …”

Table1_Overexpression of TaPIP1A enhances drought and salt stress tolerance in Arabidopsis: cross-species conservation and molecular dynamics.docx by Jie Han (128758)

“…In TaPIP1A knockout wheat strains, there was a significant decrease in stress tolerance, whereas Arabidopsis plants overexpressing TaPIP1A exhibited marked improvements in survival under similar stress conditions. …”

Fig 1 - by Taehyeong Kim (8991383)

S1 Graphical abstract - by Kevin J. Kokesh (19859571)

“…<i>avium</i> compared to vehicle. Western blot and densitometric analysis showed a significant increase in cathepsin B protein expression in <i>M</i>. …”

Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf by Mengyuan Dai (9747317)

“…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …”

S1 Data - by Hongya Liu (487440)

S1 Dataset - by Zahra Moqadassi (20490131)

“…<div><p>One of the actions taken to mitigate the climate change is research, development and demonstration (RD&D) investments in renewable energy (RE) technology. …”

Image 1_Global, regional, and national burden of nutritional deficiencies spanning from 1990 to 2021, with a focus on the impacts observed during the COVID-19 pandemic.tif by Yue-Yang Zhang (14258160)

Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

Table 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.docx by Evan Fuini (21224939)

Image1_Asymmetric dimethylarginine induces maladaptive function of the blood-brain barrier.TIF by Tetyana P. Buzhdygan (19822401)

“…Next, ADMA triggered immune-endothelial interactions since adhesion of primary human monocytes and their extravasation across the endothelial monolayer both were significantly elevated upon treatment with ADMA. Increased levels of cell adhesion molecules (VCAM-1 and RANTES), VEGF-A and inflammatory cytokines (IL-1β, TNF-α, IL-6, IL-10, IL-4, IL-2, IL-13, IL-12p70) characterize ADMA-induced hBMVEC dysfunction as inflammatory. …”

Variable evaluation and construction of a prognostic nomogram. by Kai Yang (73590)

Table 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.xlsx by Haiyan Liao (6100043)

“…RNA pull-down, RNA immunoprecipitation (RIP), and actinomycin D experiments were used to show that circ_0074158 impacts endothelial barrier function in sepsis by reducing the stability of the host gene CTNNA1 (mRNA) after binding to EIF4A3.</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”