A well-resolved phylogeny of <i>Epilobium</i> (Onagraceae) taxa in the British Isles finds no correlation between genomic divergence and the outcome of hybridisation by Kaitlin Saward (22126620)

“…</p> <p>We did not detect a significant relationship between parental divergence and hybridisation likelihood and/or hybrid fertility in <i>Epilobium</i> sect. …”

Effects of Semaglutide and Dapagliflozin on Neuronal Integrity, Apoptosis, and LRP1 Expression in the Hippocampal CA1 Region of T2DM Mice. by Yan Zhu (112437)

“…(D) Quantitative analysis of LRP1 expression shows significantly decreased levels in the T2DM group compared to control (***<i>p</i> < 0.001), while both semaglutide and da<i>p</i>agliflozin treatment significantly restored LRP1 expression compared to the T2DM group (***<i>p</i> < 0.001). …”

Variation of shear stress during the pullout of a single fiber with respect to the shear strain [41]. by Ping Gao (172038)

Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf by Faruk Hossen (20275670)

“…In the cerebral cortex and hippocampus of 12-months-old 3xTg-AD mice, we observed an upregulation of phosphorylated cPLA2 (p-cPLA2), accompanied by downregulation of Cav-1 and impaired insulin signaling. Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …”

Results of parameters a, b for curve fitting. by Hongming Li (296020)

“…The test results show that the soil expansion rate decreases from 43.7% to 37.1% with the increase of salt solution concentration. …”

Long-term changes in ABG parameters retrospectively tracked from the initiation of LTOT in the CRF group. by Kazuma Nagata (3400058)

“…<p>From five years prior to the initiation of LTOT, a decrease in PaO₂ and PaCO₂, accompanied by an increase in A-aDO₂, was observed. …”

Data Sheet 1_A home-based EEG neurofeedback treatment for chronic neuropathic pain—a pilot study.docx by Mohamed Sakel (9416397)

“…Mood scores showed a significant decrease in depression (p < 0.05), and pain catastrophizing (p < 0.05) scores improved significantly at post-intervention, with continued improvement at the first-month follow-up.…”

Data Sheet 1_Meigs syndrome was misdiagnosed as a malignant ovarian tumor: a case report.pdf by Hongmei Li (51944)

“…Notably, CA125 levels decreased from 335.1 U/ml to 164.6U/ml following surgery, and the patient showed significant clinical improvement.…”

Image_1_Education and metabolic syndrome: a Mendelian randomization study.pdf by Dong Liu (115204)

“…</p>Results<p>Education demonstrated a significant negative correlation with the risk of MetS (OR = 0.55, 95% CI = 0.48–0.63, p = 2.18E−51), waist circumference(OR = 0.80, 95% CI = 0.76–0.83, p = 4.98E-33), hypertension (OR = 0.96, 95% CI = 0.95–0.97; p = 4.54E-10), Fasting blood glucose (OR = 0.94, 95% CI = 0.91–0.97, p = 7.58E-6) and triglycerides (OR = 0.83, 95% CI = 0.79–0.87, p = 7.87E-18) while showing a positive association with high-density lipoprotein cholesterol (OR = 1.22, 95% CI = 1.18–1.25, p = 1.45E-31).…”

<i>Copia</i> and <i>dArc1</i> have an inverse relationship at the <i>Drosophila</i> NMJ. by P. Githure M’Angale (20746093)

“…Quantification of <i>dArc1</i> mRNA in the larval CNS (J), and BWM (K) of strains used in this study, showing a significant decrease of <i>copia</i> mRNA in lines with both the Gal4 driver and <i>copia</i> si/shRNA. …”

The relationship between HBV antigens deposition in kidneys and renal prognosis in IgA nephropathy patients infected with HBV by Yun Guo (135103)

“…The primary outcome was a composite of 30% decrease in eGFR from the baseline, kidney failure and all-cause mortality. …”

Table 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.docx by Wenbing Zhang (152972)

“…In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…”

Table 2_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.xlsx by Wenbing Zhang (152972)

“…In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…”

Image 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.tif by Wenbing Zhang (152972)

“…In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…”

Differential abundance comparisons between an individual plant (alfalfa, brassica, and fescue) rhizosphere and rhizospheres of plants grown in medium density (24 plants) and high d... by Derek R. Newberger (20623964)

Effects of activators and inhibitors on TcPiezo channels. by Guozhong Huang (673424)

“…Downregulation of <i>TcPiezo1</i> expression significantly decreased Dooku1-evoked TcPiezo1-mediated Ca²⁺ entry (left bar graph) but had no effect on Dooku1-evoked TcPiezo2-mediated Ca²⁺ release (right bar graph). …”

Data Sheet 1_Development of a colloidal gold-based immunochromatographic strip for rapid detection of Areca palm velarivirus 1.docx by Jie Lu (139953)

“…Background<p>Areca palm velarivirus 1 (APV1), the causal agent of betel palm yellow leaf disease (YLD), has caused significant yield losses and decreased product quality of betel nuts, posing a serious economic threat to local farmers. …”

<b><i>Escherichia coli α-hemolysin induces red blood cell retention in a microfluidic spleen-like device</i></b> by Nicolas Saffioti (9965939)

“…<p dir="ltr">α-hemolysin (HlyA) is a major exotoxin secreted by uropathogenic <i>Escherichia coli</i> (UPEC), known for its ability to lyse red blood cells (RBCs). …”

Disruption of OGG1-RNA interaction reduces RSV progeny production. by Lang Pan (5145221)

“…<p>(A) OGG1 depletion, but not NEIL2 or MTH1, reduces RSV progeny yield. …”

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip by Jung Hoon Cha (19723588)

“…</p>Conclusions<p>Our study underscores the pivotal role of CHIT1 in MASH. The observed significant improvement in inflammation and hepatic fibrosis, particularly at higher doses of the CHIT1 inhibitor, strongly suggests the potential of CHIT1 as a therapeutic target in MASH accompanied by progressive liver fibrosis.…”