Image 1_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif by Kun-Lin Lu (7256960)

“…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…”

Table 1_A two-sample bidirectional Mendelian randomization analysis between telomere length and hyperthyroidism.xlsx by Shiben Zhu (19159465)

“…Utilizing 139 genome-wide significant single nucleotide polymorphisms (SNPs) as instrumental variables (IVs) for TL, forward MR analyses indicated a negative causal effect of TL on hyperthyroidism. …”

Image1_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff by Alexandra Coello-Camba (6489533)

“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”

Table 1_Evaluating treatment and care outcomes for neuromuscular diseases in a pediatric intermediate care setting.docx by Giacomo Brisca (10963929)

Table 1_Proteomic insights into COPD pathogenesis and therapeutic targets: a causal analysis of circulating proteins.docx by Min Luo (258201)

“…Western blot analysis validated these findings in plasma samples, showing significantly increased expression of MMP12 and ASM, and decreased expression of NPNT and SNX1 in COPD patients compared to healthy controls, while KLC1 showed no significant difference. …”

Table 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx by Lili Zhou (265076)

“…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”

DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx by Jung Hoon Cha (19723588)

“…</p>Conclusions<p>Our study underscores the pivotal role of CHIT1 in MASH. The observed significant improvement in inflammation and hepatic fibrosis, particularly at higher doses of the CHIT1 inhibitor, strongly suggests the potential of CHIT1 as a therapeutic target in MASH accompanied by progressive liver fibrosis.…”

Data Sheet 1_Microbial dysbiosis in obstructive sleep apnea: a systematic review and meta-analysis.docx by Yang Guo (399435)

“…</p>Results<p>We identified a total of 753 articles, out of which 27 studies were ultimately included in the systematic review, involving 1,381 patients with OSA and 692 non-OSA populations, including 1,215 OSA patients and 537 non-OSA populations in adults and 166 OSA patients and 155 non-OSA populations in children. …”

Table 1_Interobserver variability in organ delineation on radiotherapy treatment planning for nasopharyngeal carcinoma: A dosimetric and prognostic analysis.docx by Meining Chen (18693919)

“…Compared to standard delineations, all four physicians showed decreased TCPs (average decrease in ΔTCP >1%) and a significant increase in NTCPs of OARs. …”

Image1_ASC speck serum concentrations, a component of sterile cellular inflammation, are associated with individual cardiopulmonary capacity.JPEG by Alexander Kogel (13296595)

“…Athletes with an increase in ASC speck concentrations in response to CPET had a lower peak oxygen pulse compared to those with a decrease (17.1 ± 4.2 vs. 19.8 ± 4.1, p < 0.05).…”

Data Sheet 1_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf by Tianmin Huang (20561477)

“…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …”

Image1_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.tif by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Table 1_The nature and extent of migrants, immigrants, and refugees' trust in the social institutions of their host countries: a scoping review.docx by Helena Godinho Nascimento (22335772)

“…Introduction<p>One of the most significant drivers of the public's decision-making is trust. …”

Table1_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Data Sheet 1_Acute-phase proteins as biomarkers of inflammation in HIV patients with latent tuberculosis: a prospective study.pdf by Nathella Pavan Kumar (8911094)

Supplementary file 1_Exposure-response analyses of venetoclax combined with hypomethylating agents in myelodysplastic syndromes: a retrospective study.docx by Ji-Xin Tian (21710993)

“…The use of azole antifungals was a significant factor influencing VEN concentration (P < 0.05). …”

Hypoxia response and tracheogenesis in <i>PGR</i> mutants. by Daiki Fujinaga (21301129)

“…*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001 (Student’s <i>t-</i>test <i>vs PGR</i>^<i>A1/+</i>). …”

Bioclimatic variables used for MaxEnt modeling. by Dong-Joo Kim (1797640)

“…Under the SSP5-8.5 scenario, suitable areas for <i>S. koreana</i>, <i>B. ermanii</i>, <i>T. cuspidata</i> decreased by 33.6%, 98.9%, and 90.1%, respectively. …”

Data_Sheet_1_A randomized double-blinded study assessing the effect of different doses of transnasal dexmedetomidine on the median effective concentration of ropivacaine for a caud... by Fu Wang (10556)

“…Compared to group IN-NS, the EC50 value of ropivacaine in IN-DEX2 was significantly decreased by 21.4% (p = 0.001), while there was no significant difference between group IN-NS and IN-DEX1 (p = 0.125). …”

Table 1_Plasma fibrinogen level and acute aortic dissection prognosis—insights from a two-center cohort study.pdf by Jiaxin Xiao (4423546)

“…After multivariate adjustment, each 1 g/L increase in PFL was associated with a 18.9% decrease in 30-day mortality rate and a 11.5% decrease in long-term mortality rate (P < 0.001). …”