DataSheet1_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.docx by Xiang Li (114679)

“…Glucocorticosteroids are the main therapeutic agents for it, but their efficacy is poor in some patients. Tofacitinib, a small molecule agent that inhibits JAK1/3, has shown incredible efficacy in a wide range of autoimmune diseases and maybe a new valuable treatment option for refractory BP.…”

(A, B) Western blot analysis of lysates from the two clones with the TrkB-BAC minigene (77−5 and 77−6) before and after deglycosylation and probed with an antibody recognizing TrkB... by Francesco Tomassoni-Ardori (22216521)

“…Note the significant decrease in size of both TrkB.FL and TrkB.T1 bands after deglycosylation and the presence of a single band following deglycosylation. …”

Supplementary file 1_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip by Chengna Wang (21535973)

“…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …”

Table 1_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx by Youqiong Xu (18161893)

“…Integrate healthy lifestyles and explore their association with multiple comorbidities using normal metabolism and healthy lifestyles as reference groups. PreMetS [OR = 1.38, 95%CI: 1.16–1.64] and MetS [OR = 1.61, 95%CI: 1.32–1.97] were associated with a significantly higher risk of multiple comorbidities compared with the normal population, and the risk of multiple comorbidities tended to increase as the number of metabolic disorder components increased (p < 0.001). …”

Table 1_Temporal trends and geographic disparities in thyroid cancer burden: a global analysis from 1990 to 2021.doc by Zuzhi Zhao (21724217)

“…</p>Results<p>In 2021, the global thyroid cancer burden was substantial, with 1,987,148.5 cases. From 1990 to 2021, the ASPR increased from 14.9 (95% Uncertainty Interval [UI]: 14.1–16.0) to 23.1 (95% UI: 20.7–25.6) per 100,000 population, with an EAPC of 1.58 (95% UI: 1.44–1.73); the ASIR increased from 2.1 (95% UI: 2–2.2) to 2.9 (95% UI: 2.6–3.2) per 100,000 population, with an EAPC of 1.25 (95% UI: 1.14–1.37); the ASDR declined from 0.6 (95% UI: 0.5–0.6) to 0.5 (95% UI: 0.5–0.6) per 100,000 population, with an EAPC of −0.24 (95% UI: −0.24 – −0.21); the age - standardized DALY rate decreased from 15.2 (95% UI: 14.2–16.8) to 14.6 (95% UI: 12.8–16.1) per 100,000 population, with an EAPC of −0.14 (95% UI: −0.17 – –0.11). …”

Table1_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx by Runzhou Ma (19758996)

“…</p>Results<p>After FDR correction, SE (27:1/20:4) (OR = 0.938, 95%CI = 0.906-0.972, P = 4.38 × 10^-4, PFDR = 0.039) was identified to be significantly associated with AP risk. …”

Data_Sheet_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.PDF by Meng Chen (48769)

“…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …”

Multi-State Redox and Light-Driven Switching of Pseudorotaxanation and Cation Shuttling by Robert Hein (4849108)

“…Specifically, the neutral switches can be quantitatively converted between <i>anti-</i> and <i>syn-</i>folded receptor geometries by irradiation, leading to the discovery of a significant increase or decrease in cation binding affinity, which was exploited to shuttle the pseudorotaxane-forming dibenzylammonium guest between the switchable crown ethers of slightly different sizes. …”

Table1_Association of metabolic score for insulin resistance with progression or regression of prediabetes: evidence from a multicenter Chinese medical examination cohort study.doc... by Guotai Sheng (9707713)

Decadal changes in species composition of rare oak <i>Quercus chungii</i> forests with logging history by Wenbin Li (9244088)

“…A larger contribution from balanced abundance variations than abundance gradient to the temporal <i>β </i>diversity suggested that there was no significant consistent increase or decrease in species abundance during this decade. …”

Image 1_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.tif by Chang Liu (35901)

“…The findings indicate that acupuncture significantly improves cognitive performance in SD models, evidenced by increased platform crossings [MD = 1.67, 95% CI (1.42, 1.91)] and extended time in the target quadrant [MD = 8.54, 95% CI (6.35, 10.73)], along with reduced escape latency [MD = −8.33, 95% CI (−11.68, −4.99)]. …”

Supplementary file 1_Characteristics, clinical evidence and implementation effects of conditional approvals for drugs in China, a pooled analysis from 2020 to 2023.docx by Li Yang (6520)

Data Sheet 1_Cellular respiration and amino acid metabolism is altered by dietary oligosaccharides in Salmonella with epithelial cell association.docx by Claire A. Shaw (22382332)

“…Typhimurium in ways specific to each prebiotic during infection in a focused ‘in vitro’ model.</p>Results<p>Initially, HMO and MOS addition decreased S. …”

Data Sheet 1_Correlation between cortical morphology and synaptic-associated proteins levels in poststroke aphasia: a pilot study.docx by Yun Cao (111731)

Table 1_Effects of a community pharmacy-based structured medication review on drug-related problems in all-comers with polypharmacy: a randomized, controlled, double-blind, paralle... by Thorsten Bischof (19848696)

“…Therapy adherence- and health literacy-related DRPs decreased significantly by ~60% and ~64%, respectively. …”

Table 1_Drug-induced urinary retention: a real-world pharmacovigilance study using FDA and Canada vigilance databases.docx by Xianyu Dai (18939514)

“…The median age among these cases was 65 years, with males comprising 53.4%. There were significant annual increases in UR reports associated with antineoplastic agents (0.19% per year) and antidiabetic drugs (0.09% per year), while reports linked to bronchodilators decreased (−0.53% per year). …”

Supplementary file 1_Catalpol—a compound from Rehmannia glutinosa can improve hyperlipidemia by modulating gut microbiota and endogenous metabolic pathways.zip by Xinfeng Pei (22597664)

Data Sheet 1_Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study.pdf by Po-Chun Liu (676035)

Data Sheet 1_Phyllotaxy and environmental factors influences on leaf trait dimensions in Fraxinus mandshurica: a multidimensional approach within temperate forests.docx by Mingyue Jin (257928)

“…</p>Results<p>We found that (1) specific leaf area and leaf nitrogen concentration significantly increase along the phyllotaxy gradient (from phyllotaxy 1 to 6), while leaf dry matter content, leaf thickness, and stomatal density significantly decrease. …”