Supplementary file 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.docx by Demos Kynigopoulos (12420457)

Data_Sheet_1_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF by Joseph H. Skarlupka (5830637)

“…One such factor is the color of the swab, which can vary significantly across different cows. …”

Data_Sheet_1_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF by Joseph H. Skarlupka (5830637)

“…One such factor is the color of the swab, which can vary significantly across different cows. …”

Data Sheet 1_Effect of music therapy on children with autism spectrum disorders in the Chinese population: a systematic review and meta-analysis.docx by Yajing Yang (2105431)

“…The results showed that MT significantly decreased the total ATEC (autism treatment evaluation checklist) score (SMD = -2.52, 95% CI: -3.69 ~ -1.35, P < 0.001), ABC (autism behavior checklist) (SMD = -1.07, 95% CI: -1.52 ~ -0.61, P < 0.001), and CARS (childhood autism rating scale) score (SMD = -1.50, 95% CI: -2.26 ~ -0.74, P < 0.001). …”

Data Sheet 1_Spatiotemporal dynamics and influencing factors of native and invasive saltmarshes in a rapidly silting bay during 1985–2023.docx by Mingshan Xu (15370147)

Image 1_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg by Zexin Zhang (7507979)

“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”

Table 1_WTAP modulates macrophage polarization in rheumatoid arthritis by targeting exosomal circ-CBLB via m6A modification.docx by Dawei Yan (193244)

“…Functional experiments demonstrated that WTAP overexpression decreased exosomal circ-CBLB levels and promoted macrophage polarization toward the pro-inflammatory M1 phenotype, which was reversed by m⁶A modification site mutation.…”

DataSheet1_Quantifying the effects of far-red light on lettuce photosynthesis and growth using a 3D modelling approach.docx by Jiawei Li (559407)

“…Results showed that leaf elevation angle, leaf expansion rate, and plant height significantly increased at each growth stage as the R:FR ratio decreased. …”

Table 1_Effects of biochar on phosphorus fraction, phosphatase activity, and phosphorus-solubilizing bacterial abundance: a phosphorus-depleted biochar design.docx by Hongyi Qin (5943515)

Data_Sheet_1_Effect of synbiotic supplementation on obesity and gut microbiota in obese adults: a double-blind randomized controlled trial.docx by Xiaokang Niu (13839428)

“…</p>Methods<p>In a randomized, double-blind, placebo-controlled trial, 80 individuals with obesity consumed daily synbiotics (containing MN-Gup 1 × 10¹¹ CFU/day, GOS 0.7 g/day, and XOS 0.7 g/day) or placebo for 12 weeks. …”

Data_Sheet_1_Efficacy and safety of Latilactobacillus curvatus LB-P9 on hair health: a randomized, double-blind, placebo-controlled clinical trial.docx by Sun Young Choi (793010)

“…In the test group, the hair luster parameter increased by 1.65 ± 2.30 (L_BNT) at 24 weeks (p < 0.001), indicating a 19% improvement over the control group. …”

Data Sheet 1_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.docx by Yi-Ming Ren (555968)

“…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …”

Table 1_CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration.docx by Kexin Xu (757891)

“…The neuroprotective effect of CD3ζ knockdown was accompanied by the restoration of MAPK signaling, specifically the phosphorylation of ERK and p38, and attenuation of NF-κB activation, indicated by decreased p65 phosphorylation. Furthermore, CD3ζ knockdown reduced the levels of proinflammatory mediators (IL-1β, TNF-α, and MMP-9) and increased that of the anti-inflammatory cytokine IL-10, creating a retinal microenvironment conducive to neuroprotection.…”

Data Sheet 1_Predict and prevent microvascular complications of type 2 diabetes: a cross-sectional and longitudinal study in Chinese communities.docx by Zhaoxiang Liu (9019424)

“…The risk of DKD increased more rapidly as HbA1c exceeded 7.5% and decreased as blood pressure was maintained below 120/70 mmHg. …”

Data Sheet 1_Evaluation of Lactiplantibacillus plantarum CRS 33 to therapeutic effects on a murine model of Escherichia coli-induced endometritis.zip by Mingchao Liu (1390666)

“…Female mice were induced with Escherichia coli endometritis and treated with Lactiplantibacillus plantarum CRS33 at a dose of 1 × 10^⁹ CFU/mL. Uterine morphology, wet weight index, inflammatory cell infiltration, cytokine levels (IL-6, IL-1β, IL-8, TNF-α), and uterine microbiota composition were analyzed.…”

Data Sheet 1_Identification of key genes and immune infiltration mechanisms in limb ischemia-reperfusion injury: a bioinformatics and experimental study.docx by Qiyun Shi (5531150)

“…Immune analysis revealed myeloid polarization shifts (increased M1, decreased M2 macrophages; P<0.05). WNT5A correlated negatively with memory immune cells, while PLCG, ITPR1, and CAMK2A correlated with lymphocyte subpopulations.…”

Data Sheet 1_Metastatic organ count stratifies survival in immunotherapy-treated metastatic colorectal cancer: a retrospective cohort study.docx by Hai-Yan Fu (1586935)

“…The Kaplan–Meier curve analysis and log-rank test were used to evaluate PFS across varying metastatic organ counts. Subsequently, a nomogram was constructed for PFS prediction.</p>Results<p>Patients with varying metastatic organ counts exhibited significantly different objective response rates (ORRs) (1 to ≥4 organs: 49.3%, 30.0%, 19.6%, 5.9%, respectively, P < 0.001). …”

Image 1_CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration.jpeg by Kexin Xu (757891)

“…The neuroprotective effect of CD3ζ knockdown was accompanied by the restoration of MAPK signaling, specifically the phosphorylation of ERK and p38, and attenuation of NF-κB activation, indicated by decreased p65 phosphorylation. Furthermore, CD3ζ knockdown reduced the levels of proinflammatory mediators (IL-1β, TNF-α, and MMP-9) and increased that of the anti-inflammatory cytokine IL-10, creating a retinal microenvironment conducive to neuroprotection.…”

Table 1_Prevalence and prognostic value of sarcopenia in patients with bladder cancer undergoing radical cystectomy: a systematic review and meta-analysis.docx by Lei Zhang (38117)

“…We observed that BC patients with sarcopenia had a worse OS (HR:1.64, 95% CI: 1.30 to 1.97, I² = 76.5%, P < 0.001} and CSS (HR:1.86, 95% CI: 1.45 to 2.27, I² = 0.0%, P < 0.001).…”

Table 1_Interaction between dietary selenium intake and age on severe headache or migraine in the United States: a population-based study.docx by Xinping Yu (555177)

“…The OR of developing migraine was 0.97 (95% CI: 0.94–0.98) in individuals with selenium intake ≥101.9 ug/day in adults with 20–50 years.</p>Conclusion<p>A higher dietary selenium intake is significantly associated with a decreased prevalence of migraine, and age can modify the association between them. …”