Image 1_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff by Juliana R. Zampieri (22261441)

“…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.…”

MO-SAM segmentation performance using the Grid method in the forested landscape. by Qitong Wang (15279695)

Rotarod performance. by Gerald Yu Liao (20490394)

“…<p><b>A.</b> CB6F1J mice at 20 and 28 months of age exhibited significant differences when compared to 4 and 12-month-old cohorts and showed a negative association between performance and age. …”

Ydj1 acetylation alters interactions with client proteins. by Siddhi Omkar (12413434)

“…The dotted lines represent an interaction change of Log2 > 1 or Log2 < −1. Interactors are colored according to change in interaction as follows: green (significant increase), red (significant decrease), or purple (no significant change) 6KQ/6KR. …”

Supplementary Material for: The Effectiveness of a Hospital-Based Antimicrobial Stewardship Program: A Three-Year Observational Study by figshare admin karger (2628495)

“…Resistance rates for VRE and CRE decreased (44% to26% and 47% to42%, respectively) without statistical significance. …”

Data Sheet 1_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf by Raju S. Rajmani (11134060)

“…It is one of the major global public health problems that leads to a high morbidity and mortality rate. …”

Data Sheet 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Bur... by Yangtian Jiao (21725018)

Data Sheet 1_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”

A typical cross signalized intersection. by Bin Zhao (276445)

“…Numerical experiments using actual survey data from Kunshan City yield several noteworthy findings: (1) An optimal moderate-sized time step exists for rolling optimization to minimize either the average delay time or total costs; specifically, an excessively small time step may increase vehicle average delay time or total costs; (2) The percentage of delay reduction achieved by our method, compared to Synchro software, reaches a maximum of approximately 70% when traffic demand is moderate and the initial state is low; and (3) The percentage reduction in average delay or total costs compared to Synchro initially increases and then decreases with rising traffic intensity.…”

Heterotrophic cell growth and dry cell yield of <i>Rhodovulum sulfidophilum</i> in artificial seawater (ASW) based growth medium of different salinities, wherein 100% corresponds t... by Shamitha Rao Morey-Yagi (19779981)

“…Asterisks indicate significant differences between 100% and decreasing concentrations of ASW tested using one-way ANOVA (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0321821#pone.0321821.g001" target="_blank">Figs 1b</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0321821#pone.0321821.g001" target="_blank">1c</a>) or two-way ANOVA (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0321821#pone.0321821.g001" target="_blank">Fig 1a</a>), and the Dunnett’s multiple comparison test (GraphPad Prism 9); * p < 0.05, ** p < 0.01, and *** p < 0.001.…”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Additionally, treatment with <b>19c</b> led to downregulation of key fibrosis-related genes, including α-SMA, Timp1, Col1a1, and Col3a1. Taken together, these results suggest that <b>19c</b> has the potential to be a novel antifibrotic agent.…”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Additionally, treatment with <b>19c</b> led to downregulation of key fibrosis-related genes, including α-SMA, Timp1, Col1a1, and Col3a1. Taken together, these results suggest that <b>19c</b> has the potential to be a novel antifibrotic agent.…”

DataSheet1_AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics.docx by Jingxia Du (8752482)

“…We found that Mdivi-1 significantly improved MMP, inhibited ROS production, reduced the expression of TNF-a, IL-6, IL-1β, Fis1, and Mff, and improved the expression of Mfn1 and Mfn2. …”

Image1_DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis.TIF by Minglu Meng (19725085)

“…Additionally, a decrease in methylation levels in the FGFR1 DNA promoter was detected in the serum of asthma patients using the MassARRAY technique.…”

Data Sheet 1_Saccharomyces boulardii (CNCM I-745) improves intestinal damage in sepsis by remodeling intestinal flora structure.zip by Hui-Ying Liu (10193468)

“…</p>Results<p>Sepsis led to an increase in the expression of IL-6, TNF-α, and a decrease in the expression of occludin. After treatment with S. boulardii (CNCM I-745), the inflammatory damage with sepsis was reduced, and the expression level of occludin was significantly increased. …”

Image 2_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg by Shiyu Xiao (8147688)

“…The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). In contrast, most kinds of MGDGs, HexCers, Cers, PEs and FA (18:2) demonstrated a notable decrease in the hippocampus of AD group (p < 0.05, VIP > 1).…”

Flow chart of research object screening. by Wenyao Xie (21567889)

“…In fully adjusted models, each 10 ng/dL increase in testosterone was associated with a 3.0% decrease in ALI (OR=0.970, 95%CI: 0.962–0.978, P < 0.001), while each 1 pg/mL increase in estradiol was associated with a 60.3% increase in ALI (OR=1.603, 95%CI: 1.318–1.949, P < 0.001). …”

<b><i>Original data for "High risk of soil available silicon deficiency in bamboo forest: Insights from bamboo afforestation chronosequences in the karst region of southwest China"... by Kangning Yan (22751487)

“…Furthermore, aboveground Si content decreased significantly from leaves (10.54–21.45 g kg–1) to branches (3.81–5.61 g kg–1) and culms (1.07–1.98 g kg–1). …”

Short-term antiretroviral therapy may not correct the dysregulations of plasma virome and cytokines induced by HIV-1 infection by Yingying Ma (3617810)

“…Metagenomic analysis revealed an increased abundance and prevalence of human pegivirus type 1 (HPgV-1) and a slightly decreased diversity and abundance of anellovirus in plasma of HIV-1-infected individuals after ART. …”

miR-155 directly targets the 3′UTR of TRAF3 and STAT1. by Xinyue Zhang (271120)

“…<p><b>(A)</b> The predicted target sites of miR-155 in TRAF3 and STAT1 3′UTRs, as well as the mutant forms with the potential miR-155 binding sites mutated. …”