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8181
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8182
Image 1_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.tif
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8183
Table 3_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8184
Data Sheet 4_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway....
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8185
Table 2_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8186
Table 1_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8187
Data Sheet 1_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway....
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8188
Data Sheet 2_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway....
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8189
Table 2_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8190
Table 4_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8191
Table 4_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8192
Table 5_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8193
Table 6_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8194
Data Sheet 3_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway....
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8195
Table 7_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.</p>Methods<p>A diabetic zebrafish model was established by exposure to 2% glucose for 28 days. …”
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8196
Table_1_Global burden of drug use disorders by region and country, 1990–2021.docx
Published 2024“…</p>Results<p>The global ASIR of DUDs showed a slight downward trend (EAPC = −0.26). The age-standardized DALY rate (per 100,000) significantly declined from 1990 to 2021 (EAPC = −1.44). …”
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8197
Sex hormone stimulation of CRISPR-modified HepG2 cells alters alpha-1 antitrypsin production
Published 2025“…There was also a dose-dependent decrease in AAT release, particularly in oestrogen-treated cells (Figure 1C). …”
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8198
Data Sheet 1_Sympathetic vasomotion as an early marker of hemorrhage.docx
Published 2025“…</p>Results<p>Vasomotion differences between innervated and denervated kidneys in admittance gain, phase shift, and coherence increased significantly prior to increases in heart rate or decreases in blood pressure.…”
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8199
Acteoside inhibits hepatic lipid accumulation and oxidative stress in type 2 diabetic mice via the Nrf2/HO-1 Pathway
Published 2025“…In diabetes, malondialdehyde (MDA) content was elevated in serum, accompanied by a decrease in superoxide dismutase (SOD) activity. …”
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8200
Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx
Published 2025“…TCF3 knockdown significantly attenuated these EMT changes and increased autophagy markers, as evidenced by decreased P62 levels (p < 0.01) and increased LC3-II/I ratio (p < 0.001) and Beclin-1 expression (p < 0.01). …”