DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx حسب Abdul Mateen (12055673)

"…Pharmacokinetic parameters such as AUC_0-t, C_max MRT, Vd, and half-life (t_1/2) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar^®). …"

Supplementary Material for: Characterisation of an ischaemia-reperfusion model for the formation of a stage II pressure injury in diabetic mice حسب figshare admin karger (2628495)

"…Ischemia durations of 8 and 16 h resulted in more severe full-thickness skin defects, including exposed subcutaneous adipose tissue and inward contraction of wound margins. After ischaemia (I) for 4 h and reperfusion (R) for 24 h, the morphology of fibroblasts in the compressed skin area of db/db mice changed, and the expression of TGF-β1 decreased significantly compared with those in WT mice. …"

Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf حسب Oliver Küppers (22742732)

"…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. …"

Table 1_Opposing effects of sugar-free claims on perceived healthiness and sweetness reduce consumers’ willingness to pay for sugar-free products.docx حسب Ksenia Panidi (5991186)

"…However, this positive effect was overridden by a significant decrease in perceived tastiness and sweetness of products labeled as sugar-free compared to sugar-containing ones, which in turn led to a reduction in the willingness to pay. …"

Table 1_Effects of silver nanoparticles on the physiology, stress, and mineral uptake of banana cultivars in vitro and greenhouse.xlsx حسب Natalia Mendoza (22038296)

"…Rooting experiments revealed similar trends with high AgNP concentrations resulting in a decreasing root number and size. Greenhouse experiments on Gros Michel bananas, evaluating AgNP uptake through foliar and drench applications at 0, 25, 50, and 100 mg L^-1, monitored over a month, showed no statistically significant differences in growth parameters between treated plants and controls. …"

Image 1_Effects of silver nanoparticles on the physiology, stress, and mineral uptake of banana cultivars in vitro and greenhouse.tiff حسب Natalia Mendoza (22038296)

"…Rooting experiments revealed similar trends with high AgNP concentrations resulting in a decreasing root number and size. Greenhouse experiments on Gros Michel bananas, evaluating AgNP uptake through foliar and drench applications at 0, 25, 50, and 100 mg L^-1, monitored over a month, showed no statistically significant differences in growth parameters between treated plants and controls. …"

Measurement of interference efficiency of AjNLRC4 or AjCASP-1 by specific siRNA transfection. حسب Kaiyu Chen (11691918)

"…Finally, the relative expression of AjNLRC4 (a) or AjCASP-1 (b) in coelomocytes was determined at mRNA levels by using qPCR and at protein levels by western blotting analysis. …"

Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg حسب Katrina S. Hofstetter (17545425)

"…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …"

Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg حسب Katrina S. Hofstetter (17545425)

"…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …"

Data Sheet 1_Consistent microbial responses during the aerobic thaw of Alaskan permafrost soils.docx حسب Joy M. O’Brien (18927811)

Table 1_Therapeutic potential of Cervi Cornus Colla in zebrafish bone injury: implications for aquaculture.docx حسب Fengxia Xu (20175965)

"…</p>Results<p>The median lethal concentration (LC₅₀) of CCC in zebrafish was 206.3 mg/mL, and staining revealed that CCC reversed LPS-induced reduction in cartilage and bone formation in a dose-dependent manner. In Tg (mpeg1: EGFP) zebrafish, CCC treatment significantly decreased macrophages-associated green fluorescence, suggesting that the extract suppressed the activation of macrophages caused by LPS. …"

Table 1_Declining trends in sweetness of the diet in the United Kingdom: 2008/9–2018/19.docx حسب Inga Kutepova (20873687)

"…Overall, the decline in ASE was larger for beverages than foods (ASE values declined 20.7% for beverages vs. 4.4% for foods), although both decreased significantly (p-value < 0.01). Dietary sweetness has changed in the UK, due to a combination of consumer behavior, reformulations, policies, public health awareness programs, and media campaigns, emphasizing its multifactorial nature.…"

Table 1_Chicory supplementation improves growth performance in juvenile ostriches potentially by attenuating enteritis.xlsx حسب Meng Li (79487)

"…The supplementation of CA at a dose of 80 mg/kg significantly increased the expression level of ZO-1 and claudin-3 (p < 0.0001) and suppressed the levels of IL-1β, IL-6, and TNF-α (p < 0.0001) in ostriches with LPS-induced ileitis.…"

Table 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.docx حسب Jing Lv (128179)

"…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …"

Image 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.tif حسب Jing Lv (128179)

"…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …"

DataSheet1_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx حسب Hongyang Guo (9466516)

"…The phenotypic traits, resistance indicators, and transcriptional and metabolic regulation of MdKAI2 were identified. KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. …"

Supplementary Material for: Successful Management of Post-Thymectomy Pure Red Cell Aplasia with Rituximab: A Case Report حسب Abdulgayoom M. (17726475)

Table 1_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.docx حسب Xiaodong Wang (66801)

"…The experimental results showed that β-sitosterol could significantly inhibit the excessive proliferation of MH7A cells (p< 0.05). …"

Image 1_Effects of phospholipase C inhibition on the regulation of membrane lipid metabolism in maize leaves.jpeg حسب Yulei Wei (4840461)

Table 1_Effects of phospholipase C inhibition on the regulation of membrane lipid metabolism in maize leaves.xlsx حسب Yulei Wei (4840461)