First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…Here we report the design, synthesis, and biological activity of six analogues of the natural hormone 1,25-dihydroxyvitamin D3 (1,25D₃), which incorporate a silicon atom as a side chain-C25 isostere. …”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…Here we report the design, synthesis, and biological activity of six analogues of the natural hormone 1,25-dihydroxyvitamin D3 (1,25D₃), which incorporate a silicon atom as a side chain-C25 isostere. …”

Image 2_Integrating salpingoscopy and immunohistochemistry to improve tubal infertility diagnosis: a retrospective cohort study.jpeg by Adalyat Alenova (22696712)

“…Introduction<p>Tubal factor infertility is one of the most prevalent and diagnostically complex causes of female infertility. …”

Table 1_Association of cardiovascular health with reproductive lifespan and pregnancy loss: insights from NHANES 2005–2018.pdf by Yang Yan (222441)

Supplementary Material for: Exclusively macular phenotype of non-syndromic MFSD8-related disease: A Case Report by figshare admin karger (2628495)

“…Introduction: The purpose of this report is to highlight the clinical phenotype and imaging findings in a patient with an exclusively macular phenotype of non-syndromic MFSD8-related disease, and to provide clinical evidence for pathogenicity reclassification of a variant of uncertain significance (VUS) MFSD8 c.291G>C (p.Trp97Cys). …”

Photon budgets and the effects of relative CDOM and pigment absorptions on primary production along a coastal salinity gradient by Aleksandr Berezovski (20459366)

DataSheet1_Network meta-analysis of integrated traditional Chinese and Western medicine in the treatment of Sjogren’s syndrome.pdf by Xieli Ma (20153298)

“…</p>Conclusion<p>TCM combined with CWM has a very significant effect on treating SS compared with CWM alone. …”

Table 1_Influence of summer transhumance practice in the Carpathians, Apuseni Mountains, Romania, on cattle milk production and quality.doc by Mirela Ranta (22613816)

<b>Epigenetic signatures of treatment with intravenous furosemide plus hypertonic saline solution in decompensated heart failure patients: A Randomized Controlled Trial ( RCT)</b> by Antonino Tuttolomondo (3222708)

“…In terms of differentially expressed miRNAs, we observed a decrease in the expression of miR181b in subjects treated with i.v. furosemide plus HSS in comparison to patients treated with i.v. furosemide alone and a more significant reduction of miRNA181b expression in subjects treated with furosemide plus HSS. …”

Table 1_Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway.docx by Yuru Pang (20944667)

“…</p>Methods<p>Recently, we synthesized a novel iridium (III) complex (Ir-1) and evaluated its safety and stability. …”

Table 1_Integrative transcriptome and WGCNA analysis reveal key genes mainly in response to Alternaria alternata in Populus simonii × P. nigra.xlsx by Siyuan Liu (696701)

“…Within these modules, we also identified hub genes in the regulatory network, including GLK1/2 transcriptional activators, 14-3-3 proteins, cytosine 5 methyltransferases, and a variety of proteins associated with photosynthesis and respiration. …”

Data Sheet 1_Particulate matter pollution and older adult health: global trends and disparities, 1991–2021.docx by Qiong Yi (3931826)

“…Females consistently experienced higher age-standardized DALYs rate than males for both APMP and HAP-SF across all regions and years. APMP burden showed a weak negative correlation with the Socio-demographic Index (SDI) at the regional level (r = −0.25, p < 0.001) but no significant correlation at the country level. …”

Image 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..tif by Felicia Menicucci (7495508)

Table 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..docx by Felicia Menicucci (7495508)

Data Sheet 1_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.pdf by Chaofeng Niu (17746406)

Table 1_Global, regional and national patterns and gender disparity of intraocular foreign bodies from 1990 to 2021.doc by Yi Shan (160293)

“…Pearson’s correlations (r = 0.3093, p < 0.001) and linear regression (Y = 4.850*X − 1.857) revealed a significant positive association between gender differences and SDI. …”

Glial 5-HT_2a receptors are necessary and rate limiting for experience-dependent synaptic glomeruli pruning. by Vanessa Kay Miller (19775496)

“…The Or42a OSN innervation volume with glial <i>5-HT</i>_<i>2A</i><i>R</i> OE is very significantly decreased in comparison to the control EB condition (<i>p</i> = 4.64 × 10⁻¹⁰). …”

Supplementary file 1_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx by Omar Z. Ameer (8900039)

“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”

Data Sheet 1_Artificial clicks (Porpoise ALert) affect acoustic monitoring of harbour porpoises and their echolocation behaviour.pdf by Joseph G. Schnitzler (12084395)

Image2_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg by Adam D. Price (19842741)

“…‘Immunocompetent’ endotype patients on day 1 had a higher proportion of favorable to non-favorable discharges compared to the ‘immunosuppressed’ endotype. …”