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12361
Data Sheet 2_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx
Published 2025“…Single-cell resolution analysis showed HSP90AA1 to be specifically overexpressed in oligodendrocytes (72.23%), significantly correlating with glial depletion (4.56% decrease in oligodendrocytes, p<0.01) and aberrant neuronal proliferation (144.23% increase, p=0.0032). …”
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12362
Data Sheet 3_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx
Published 2025“…Single-cell resolution analysis showed HSP90AA1 to be specifically overexpressed in oligodendrocytes (72.23%), significantly correlating with glial depletion (4.56% decrease in oligodendrocytes, p<0.01) and aberrant neuronal proliferation (144.23% increase, p=0.0032). …”
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12363
Data Sheet 4_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx
Published 2025“…Single-cell resolution analysis showed HSP90AA1 to be specifically overexpressed in oligodendrocytes (72.23%), significantly correlating with glial depletion (4.56% decrease in oligodendrocytes, p<0.01) and aberrant neuronal proliferation (144.23% increase, p=0.0032). …”
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12364
Supplementary Material for: Conversion Ability of Immunotherapy in Hepatocellular Carcinoma: Insights from the International Converse Study
Published 2025“…A significant discrepancy was observed between PC (16% and 13% for AB and LENV, p=0.03) and AC rates (3% for both AB and LENV, p=0.14). …”
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12365
Table 6_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx
Published 2025“…In contrast, FLNA levels measured by ELISA showed a progressive decrease from healthy controls to patients with inflammatory polyps and further to those with adenomas. …”
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12366
Table 2_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx
Published 2025“…In contrast, FLNA levels measured by ELISA showed a progressive decrease from healthy controls to patients with inflammatory polyps and further to those with adenomas. …”
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12367
Table 3_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx
Published 2025“…In contrast, FLNA levels measured by ELISA showed a progressive decrease from healthy controls to patients with inflammatory polyps and further to those with adenomas. …”
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12368
Table 4_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx
Published 2025“…In contrast, FLNA levels measured by ELISA showed a progressive decrease from healthy controls to patients with inflammatory polyps and further to those with adenomas. …”
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12369
Table 5_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx
Published 2025“…In contrast, FLNA levels measured by ELISA showed a progressive decrease from healthy controls to patients with inflammatory polyps and further to those with adenomas. …”
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12370
Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology...
Published 2025“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
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12371
Data Sheet 3_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology...
Published 2025“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
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12372
Video 2_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov
Published 2025“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”
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12373
Video 3_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov
Published 2025“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”
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12374
Video 5_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov
Published 2025“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”
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12375
Video 4_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov
Published 2025“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”
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12376
sRAGE accelerates regeneration in aged skeletal muscle after cryoinjury.
Published 2025“…Data analyzed for statistical significance by one-way ANOVA with Tukey post hoc test (A, D, G) or Student’s two-tailed unpaired t test (E, H, J, K, L, M). …”
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12377
Supplementary file 2_Wuzi-Yanzong-Wan inhibits testicular mitochondrial apoptosis in rats by downregulating TAp73-Mediated P38 MAPK-ADAM17 pathway.docx
Published 2025“…Mechanistic investigations revealed that WZYZW markedly suppressed germ cell apoptosis (flow cytometry confirmed a significant decrease in apoptotic cell proportion) and attenuated DNA damage (indicated by significantly reduced γ-H2AX (a DNA damage marker) fluorescence intensity). …”
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12378
Table 2_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx
Published 2025“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”
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12379
Table 3_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx
Published 2025“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”
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12380
Table 4_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx
Published 2025“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”