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12901
Data Sheet 3_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip
Published 2025“…The incidence rates were stable or declined in high-income countries (e.g., high-income North America: EAPC = −1.07, 95% CI: −1.82–−0.32), whereas industrializing regions showed significant increases (e.g., East Asia: EAPC = 2.01, 95% CI: 1.02–3.19). …”
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12902
Data Sheet 4_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip
Published 2025“…The incidence rates were stable or declined in high-income countries (e.g., high-income North America: EAPC = −1.07, 95% CI: −1.82–−0.32), whereas industrializing regions showed significant increases (e.g., East Asia: EAPC = 2.01, 95% CI: 1.02–3.19). …”
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12903
Table 2_Genomic characterization and antibiotic susceptibility of biofilm-forming Borrelia afzelii and Borrelia garinii from patients with erythema migrans.pdf
Published 2025“…Core genome analysis showed 38.9% of genes were shared between B. afzelii and B. garinii, decreasing to 26.1% with B. burgdorferi. The cloud genome expanded from 34.4% to 53.4% with the addition of B. burgdorferi. …”
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12904
Table 2_Serum levels of interleukin-17, -18, -22, and -25 in patients with bullous pemphigoid before and after treatment.xlsx
Published 2025“…A binary multivariate logistic regression analysis indicated the statistically significant effect of IL-18, IL-25, or EOS on BP (p < 0.001). …”
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12905
Image_2_Mechanical acupuncture at HT7 attenuates alcohol self-administration in rats by modulating neuroinflammation and altering mPFC-habenula-VTA circuit activity.TIF
Published 2024“…</p>Discussion<p>These results suggest that HT7 stimulation regulates the mPFC-Hb-VTA circuit, leading to decreased alcohol-seeking behavior. Our study demonstrates that HT7 acupuncture can modulate the mPFC-Hb-VTA circuit, providing a potential non-pharmacological treatment for alcohol-seeking behavior by influencing microglial activity, sigma 1 receptor expression, and TH levels. …”
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12906
Image 2_The gut microbiota in liver transplantation recipients during the perioperative and postoperative recovery period.jpeg
Published 2025“…Metagenomic sequencing, analyzed using the LEfSe method, identified a total of 50 genera that played significant roles in this process. …”
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12907
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12908
Supporting data for <b>Drivers, Composition and Potential for Innovative Vector Control Approaches in the mosquito</b>
Published 2025“…Current approaches are limited to testing several bacteria in the hope that one will be effective. By analysing transcriptomics samples from previously published <i>Aedes albopictus</i> sequencing, we correlated the presence or absence of microbial taxa with the expression of a panel of immune genes. …”
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12909
Table 4_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx
Published 2025“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”
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12910
Table 2_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx
Published 2025“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”
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12911
Table 3_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx
Published 2025“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”
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12912
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12913
Supplementary Material for: Status of inpatients with pediatric epilepsy in children’s hospitals in China (2016–2021)
Published 2024“…The disease burden decreased from 17.26% to 12.11% with a significant upward trend (P=0.02417, R2=0.8817). …”
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12914
Neurodevelopmental H2AK119ub enrichment within H3K4me3-positive promoters subdues transcription.
Published 2025“…<b>(J)</b> RNAseq data within genes possessing H3K4me3-only promoters that experienced a significant increase in H2AK119ub. <b>(K)</b> RNAseq data within genes possessing bivalent promoters that experienced a significant increase in H2AK119ub. …”
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12915
Data Sheet 2_Silicon and potassium synergistically alleviate salt stress and enhance soil fertility, nutrition, and physiology of passion fruit seedlings.pdf
Published 2025“…Foliar nutrient concentrations improved while leaf Na<sup>+</sup> decreased. Biochemically, there was a significant increase in total chlorophyll, along with reduced proline levels. …”
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12916
Supplementary file 2_Quantile regression application to identify key determinants of malnutrition in five West African countries of Gabon, Gambia, Liberia, Mauritania, and Nigeria....
Published 2025“…Background<p>Malnutrition remains one of the most pressing health challenges, particularly in developing nations across Africa, placing a significant burden on both public health agencies and the affected countries. …”
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12917
Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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12918
Image 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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12919
Table 3_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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12920
Table 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”