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13161
Supplementary file 5_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR<sup>+</sup> Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”
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13162
Supplementary file 6_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR<sup>+</sup> Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”
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13163
Supplementary file 3_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR<sup>+</sup> Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”
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13164
Supplementary file 2_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR<sup>+</sup> Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”
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13165
All data.
Published 2025“…These metabolites are implicated in pathways such as bile acid metabolism, fatty acid oxidation, and neurotransmitter regulation, suggesting that inulin may exert neuroprotective effects by restoring metabolic homeostasis in a stage-dependent manner. Furthermore, rectification of gut dysbiosis by dietary inulin administration, with a major impact on increasing intestinal beneficial bacteria |(<i>Bacteroides</i> and <i>Cyanobacteria</i>) and decreasing pro-inflammatory bacteria (<i>Ruminiclostridium_6</i>, <i>Mucispirillum, Deferribacteres</i> and <i>Tenericutes</i>), exerted a close and complex interactions with metabolites, inflammatory factors, and peripheral neuropathic indicators. …”
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13166
Figure 5 from Multiplexed Imaging Mass Cytometry Reveals Tumor-immune Microenvironment–dependent Hormone Receptor Expression in Adult-Type Ovarian Granulosa Cell Tumors
Published 2025“…Colors of heatmap display gene expression <i>Z</i>-scores that are computed on a gene-by-gene basis: Increased expression (red) and decreased expression (blue). …”
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13167
Table 2_Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.docx
Published 2025“…The levels of IgM were significantly reduced following treatment (MD = −0.48, 95%CI: −0.65, −0.31), both at 6-month (MD = −1.05, 95%CI: −1.57, −0.52) and 12-month (MD = −0.59, 95%CI:−0.80, −0.38) follow-ups. …”
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13168
Table 4_Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.docx
Published 2025“…The levels of IgM were significantly reduced following treatment (MD = −0.48, 95%CI: −0.65, −0.31), both at 6-month (MD = −1.05, 95%CI: −1.57, −0.52) and 12-month (MD = −0.59, 95%CI:−0.80, −0.38) follow-ups. …”
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13169
Table 3_Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.docx
Published 2025“…The levels of IgM were significantly reduced following treatment (MD = −0.48, 95%CI: −0.65, −0.31), both at 6-month (MD = −1.05, 95%CI: −1.57, −0.52) and 12-month (MD = −0.59, 95%CI:−0.80, −0.38) follow-ups. …”
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13170
Table 4_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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13171
Table 2_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.docx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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13172
Table 3_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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13173
The quality metrics of 4C-seq data.
Published 2025“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
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13174
Uncropped western blot images.
Published 2025“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
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13175
The values used to build graphs in the paper.
Published 2025“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
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13176
The PCR primers of constructed vectors.
Published 2025“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
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13177
Data and code from: Limited responses of lizard assemblages to experimental fire regimes in an Australian tropical savanna
Published 2025“…Species richness decreased with increased fire frequency and showed a humped relationship with woody cover. …”
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13178
Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel
Published 2025“…<p><i>Metarhizium robertsii</i>, a fungal pathogen employed in pest biocontrol, can alkalize the surrounding environment, although the biological implications remain unclear. …”
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13179
Long-Term Effects of Adalimumab in Juvenile Idiopathic Arthritis-Associated Uveitis: 3- and 6-Year Results of the ADJUVITE Trial
Published 2025“…The mean dose of methotrexate decreased significantly from 11.3 ± 4.4 mg/week at the end of the trial to 5.2 ± 6.2 mg/week at the last follow-up (<i>p</i> = 0.002). …”
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13180
Value ranges of three representative points.
Published 2025“…Numerical experiments using actual survey data from Kunshan City yield several noteworthy findings: (1) An optimal moderate-sized time step exists for rolling optimization to minimize either the average delay time or total costs; specifically, an excessively small time step may increase vehicle average delay time or total costs; (2) The percentage of delay reduction achieved by our method, compared to Synchro software, reaches a maximum of approximately 70% when traffic demand is moderate and the initial state is low; and (3) The percentage reduction in average delay or total costs compared to Synchro initially increases and then decreases with rising traffic intensity.…”