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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
i.e decrease » we decrease (Expand Search), sizes decrease (Expand Search), teer decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
i.e decrease » we decrease (Expand Search), sizes decrease (Expand Search), teer decrease (Expand Search)
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Vps34 supports Treg maintenance in lymphoid and non-lymphoid tissues.
Published 2025“…GSEA enrichment plots showing increased cTreg signature (left; i.e., top 200 upregulated genes [log<sub>2</sub>FC > 0.5, FDR < 0.05] in cTregs versus eTregs) and decreased eTreg signature (right; i.e., top 200 upregulated genes [log<sub>2</sub>FC > 0.5, FDR < 0.05] in eTregs versus cTregs) in CD45.2<sup>+</sup> Tregs from <i>Foxp3</i><sup>Cre</sup><i>Pik3c3</i><sup>fl/fl</sup> mixed BM chimera mice compared to control mixed BM chimera mice. …”
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Chromatin accessibility analysis of perinatal Vps34-deficient Tregs.
Published 2025“…Relative (normalized to average control in each experiment) fold-change comparisons between genotypes in each cell type are shown in bold (<b>A</b>, <b>B</b>). Data are shown as mean ± s.e.m. (<b>A</b>, <b>B</b>). Two-tailed Student <i>t</i> test (<b>A</b>, <b>B</b>, <b>I</b>), Benjamini–Hochberg test (<b>C</b>), Wilcoxon rank-sum test (<b>G</b>), Fisher’s exact tes<i>t</i> (<b>H</b>), or binomial test (<b>J</b>); NS, not significant. …”
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Vps34 orchestrates transcriptional and epigenetic remodeling events corresponding to terminal eTreg differentiation during perinatal life.
Published 2025“…See also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.s017" target="_blank">S9 Table</a>. Data are shown as mean ± s.e.m. (<b>D</b>). Wilcoxon rank-sum test (<b>A</b>, <b>B</b>; <b>J</b>, right), Benjamini–Hochbert test (<b>C</b>), two-tailed Student <i>t</i> test (<b>D</b>, <b>I</b>), Fisher’s exact test (<b>F</b>–<b>H</b>), or bionomial test (<b>J</b>, left); NS, not significant. …”
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