Data Sheet 1_The role of statins in dementia or Alzheimer’s disease incidence: a systematic review and meta-analysis of cohort studies.docx by Ye Du (4067569)

“…Similarly, an analysis of 19 studies comprising 1,237,341 participants demonstrated a 29% decrease in the risk of AD among statin users (HR: 0.71, 95% CI: 0.60–0.85). …”

Image1_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.tif by Guangli Xia (19834830)

“…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …”

Table 2_Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome.xlsx by Jiaqi Liu (309587)

“…</p>Results<p>There were significant differences in metabolic profiles among the UA, AMI and control groups. …”

Comparative impact of fractionated and acute doses of gamma irradiation on the rats’ brain after whole body irradiation by Manal Mohammed (3453335)

“…In a different manner, TGF-β at (8 Gy) showed significant unique decrease in contrast to the substantial increase after exposure to (8 Gy/4) irradiation.…”

Immune cell subsets and cytokine levels in peripheral blood between healthy donors and triple-negative breast cancer (TNBC) patients and in patients before and after the first phas... by Nicole Chicken (19806183)

“…This study showed an increase in the percentage of CD14⁺ monocytes and CD56^high NK cells and a decrease in CD19⁺ B-cells after first-phase chemotherapy, while no significant differences in cell percentages were seen between healthy donors and treatment-naïve patient groups. …”

Image 7_The effect of COVID-19 and sex differences on natural killer cell cytotoxicity.tif by Arushi Dagar (22287460)

“…To study the function of NK cells in patients hospitalized with COVID-19, peripheral blood was obtained from patients admitted to the medical (non-ICU) wards at a large tertiary hospital. We demonstrated a decrease in the mature cytotoxic subset of NK cells within the peripheral blood of patients hospitalized with COVID-19. …”

Immunogenicity persistence after four intramuscular triple-dose or standard-dose hepatitis B vaccine in patients receiving methadone maintenance treatment: A 1-year follow-up study... by Xinyuan Mo (15468948)

“…No significant differences were observed in the persistence of vaccine-induced responses among the three groups (<i>p</i> = .204). …”

Table_2_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.doc by Sofia Priyadarsani Das (17830028)

“…The diet containing L. acidophilus at 1 × 10⁷ CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. Moreover, it upregulated several physiological pathways such as carbohydrate metabolism, signal transduction, lipid metabolism, nucleotide metabolism, amino acid metabolism, and environmental adaptation, which led to the upregulation of the AMPK, MAPK, P13K-Akt, lysosome, peroxisome, and ferroptosis signaling pathways; this enhanced growth and immunity in white shrimp. …”

Data Sheet 1_Effect of purpose-directed acupuncture on the pharyngeal phase in stroke patients with dysphagia based on surface electromyography: a randomized controlled trial.pdf by Yan-Qiang Qin (21442067)

“…Compared to the control group, the treatment group showed a significant increase in FOIS scores and a decrease in SSA scores. …”

Table 1_Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome.xlsx by Jiaqi Liu (309587)

“…</p>Results<p>There were significant differences in metabolic profiles among the UA, AMI and control groups. …”

Table 1_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.docx by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”

Data Sheet 1_Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function.docx by Amy K. Stark (20470996)

“…</p>Results<p>Prostaglandin E2 (PGE2) stimulation of retinal endothelial monolayers caused a decrease in barrier permeability in electric cell-substrate impedance sensing (ECIS) assays and dextran flux assays. …”

Primer sequences for target genes. by Yongle Du (3992198)

“…Metabonomic analysis revealed significant changes in 13 serum metabolites, with ZJP reversing the expression of 5 key metabolites. …”

Table4_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.docx by Guangli Xia (19834830)

“…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …”

Data Sheet 1_Phyllotaxy and environmental factors influences on leaf trait dimensions in Fraxinus mandshurica: a multidimensional approach within temperate forests.docx by Mingyue Jin (257928)

“…</p>Results<p>We found that (1) specific leaf area and leaf nitrogen concentration significantly increase along the phyllotaxy gradient (from phyllotaxy 1 to 6), while leaf dry matter content, leaf thickness, and stomatal density significantly decrease. …”

Image 1_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg by Shiyu Xiao (8147688)

“…The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). In contrast, most kinds of MGDGs, HexCers, Cers, PEs and FA (18:2) demonstrated a notable decrease in the hippocampus of AD group (p < 0.05, VIP > 1).…”

Image 1_Muscle fascicle length adaptations to high-velocity training in young adults with cerebral palsy.jpeg by Tessa L. Gallinger (21346835)

“…</p>Results<p>HVT resulted in a significant increase in fascicle length in CP-T (+1.92 ± 3.21 mm, p < 0.005) compared to a significant decrease in CP-NT (−1.63 ± 3.00 mm, p < 0.013). …”

Image_1_Exploring the association between phytopharmaceutical use and antibiotic prescriptions in upper respiratory infections: results from a German cohort study evaluating the im... by Anna-Jasmin Wetzel (17837840)

“…</p>Conclusion<p>Prescriptions of phytopharmaceuticals were significantly associated with a decrease antibiotic prescriptions among GPs, especially when combined with naturopathy qualifications. …”

Data_Sheet_1_Efficacy and safety of Latilactobacillus curvatus LB-P9 on hair health: a randomized, double-blind, placebo-controlled clinical trial.docx by Sun Young Choi (793010)

“…The subjective indicator of participant satisfaction, which improves as survey scores decrease, significantly decreased in the test group by −17.81 ± 14.35 points (p < 0.001) after 24 weeks of consuming the test food than before consuming it. …”

Table2_Balancing welfare and habitat damage in pigs (Sus scrofa) under extensive farming: an ethological approach for determining the effects of group composition and environmental... by Edoardo Collarini (10146350)

“…In enrichment conditions with straw, we found a significant decrease in anxiety-related, affiliation, and excavation behaviours levels, and a significant increase in non-invasive exploration behaviours. …”