Supplementary file 1_Short-term fasting before living kidney donation has an immune-modulatory effect.pdf by Christiaan A. J. Oudmaijer (12006320)

“…STF changes the levels and phenotype of immune cells, reducing the abundance and activation of T cells, including regulatory T cells, increased presence of (naïve) B cells, and elevation of type 1 conventional DCs (cDC1s). In addition, a decrease in central memory T cells was observed.</p>Discussion<p>In this study, we observed significant changes due to fasting in B cells, T cells, and DCs, specifically toward less specialized lymphocytes, suggesting an arrest in B and T cell development. …”

Table 1_Effect of acarbose and vildagliptin on plasma trimethylamine N-oxide levels in patients with type 2 diabetes mellitus: a 6-month, two-arm randomized controlled trial.docx by Xinhui Yang (12051251)

“…Intragroup analysis indicated a significant decrease in TMAO levels at 6 months compared with baseline (adjusted p<0.05). …”

Image 2_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg by Shiyu Xiao (8147688)

“…The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). In contrast, most kinds of MGDGs, HexCers, Cers, PEs and FA (18:2) demonstrated a notable decrease in the hippocampus of AD group (p < 0.05, VIP > 1).…”

Table 1_Propolis supplementation on inflammatory and oxidative stress biomarkers in adults: a systematic review and meta-analysis of randomized controlled trials.docx by Hossein Bahari (16704768)

“…This meta-analysis revealed that propolis consumption led to a significant decrease in C-reactive protein (CRP) (WMD: –1.23; 95%CI: –1.76, –0.69; p < 0.001), Interleukin-6 (IL-6) (WMD: –1.52; 95%CI: –2.10, –0.93; p < 0.001), Tumor necrosis factor-α (WMD: –1.15; 95%CI: –1.75, –0.55; p < 0.001), and Monocyte chemoattractant protein-1 (MCP-1) (WMD: –35.33; 95%CI: –50.28, –20.37; p < 0.001), and a significant increase in total antioxidant capacity (TAC) (WMD: 0.32; 95%CI: 0.12, 0.51; p = 0.001), Glutathione (GSH) (WMD: 4.71; 95%CI: 3.17, 6.25; p < 0.001), and Glutathione peroxidase (GPx) (WMD: 44.75; 95%CI: 5.10, 84.40; p = 0.02). …”

Data Sheet 1_Short-term fasting before living kidney donation has an immune-modulatory effect.docx by Christiaan A. J. Oudmaijer (12006320)

“…STF changes the levels and phenotype of immune cells, reducing the abundance and activation of T cells, including regulatory T cells, increased presence of (naïve) B cells, and elevation of type 1 conventional DCs (cDC1s). In addition, a decrease in central memory T cells was observed.</p>Discussion<p>In this study, we observed significant changes due to fasting in B cells, T cells, and DCs, specifically toward less specialized lymphocytes, suggesting an arrest in B and T cell development. …”

Supplementary file 1_Effects of a personalized PERMA-based intervention on the mental health of junior high school students: a randomized clinical trial.docx by Lei Zhang (38117)

“…No significant changes were observed in coping styles, though slight improvements in positive coping tendency (from −0.02 to −0.13) and a slight decrease in negative coping tendency (from −0.02 to −0.01).…”

Table_1_Exploring the association between phytopharmaceutical use and antibiotic prescriptions in upper respiratory infections: results from a German cohort study evaluating the im... by Anna-Jasmin Wetzel (17837840)

“…</p>Conclusion<p>Prescriptions of phytopharmaceuticals were significantly associated with a decrease antibiotic prescriptions among GPs, especially when combined with naturopathy qualifications. …”

Image 1_Temporal trends and epidemiological impact of metabolic risk factors on stroke burden in Chinese individuals aged 65 and older, 1992–2021.tif by Haiying Wang (6869)

“…High fasting plasma glucose (HFPG), high LDL cholesterol (LDL-C), and high systolic blood pressure (SBP) are significant metabolic risk factors contributing to the increasing stroke burden. …”

Video1_Balancing welfare and habitat damage in pigs (Sus scrofa) under extensive farming: an ethological approach for determining the effects of group composition and environmental... by Edoardo Collarini (10146350)

“…In enrichment conditions with straw, we found a significant decrease in anxiety-related, affiliation, and excavation behaviours levels, and a significant increase in non-invasive exploration behaviours. …”

Table 3_Effect of acarbose and vildagliptin on plasma trimethylamine N-oxide levels in patients with type 2 diabetes mellitus: a 6-month, two-arm randomized controlled trial.docx by Xinhui Yang (12051251)

“…Intragroup analysis indicated a significant decrease in TMAO levels at 6 months compared with baseline (adjusted p<0.05). …”

Table 2_Effect of acarbose and vildagliptin on plasma trimethylamine N-oxide levels in patients with type 2 diabetes mellitus: a 6-month, two-arm randomized controlled trial.docx by Xinhui Yang (12051251)

“…Intragroup analysis indicated a significant decrease in TMAO levels at 6 months compared with baseline (adjusted p<0.05). …”

Table1_Balancing welfare and habitat damage in pigs (Sus scrofa) under extensive farming: an ethological approach for determining the effects of group composition and environmental... by Edoardo Collarini (10146350)

“…In enrichment conditions with straw, we found a significant decrease in anxiety-related, affiliation, and excavation behaviours levels, and a significant increase in non-invasive exploration behaviours. …”

PRMT5 regulates alternative splicing landscape under hypoxia. by Srinivas Abhishek Mutnuru (22513457)

“…<p><b>A)</b> Pie chart showing distribution of different types of significant AS events (FDR < 0.05) in shCTRL vs. shPRMT5 MDA-MB-231 cells under hypoxia. …”

Table1_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

Data Sheet 1_Gut microbiota interacting with vitamin D but not anandamide might contribute to the pathogenesis of preeclampsia: a preliminary study.pdf by Xiao-Qiang Han (596982)

“…Compared with the LP group, the relative abundances of Prevotella, Erysipelotrichaceae_UCG-003, and Dorea were increased dramatically in the PE group, whereas the relative abundances of Subdoligranulum, Parabacteroides, Bacteroides were significantly decreased in the PE group. Furthermore, women with PE had a substantially lower plasma level of AEA and a marked decrease in serum VitD compared to normal late-pregnant women. …”

Table3_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Data Sheet 1_UV-LED disinfection of emerging Vibrio pathogens: inactivation kinetics and reactivation potential.pdf by Leonardo Romero-Martínez (22335241)

“…Introduction<p>The Vibrio genus includes aquatic bacteria from freshwater, estuarine, and marine environments, some of which pose significant risks to public and environmental health, highlighting the need for effective disinfection strategies. …”

Image 4_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”

Table 3_The impact of the herd health interventions in small ruminants in low input production systems in Ethiopia.docx by Mesfin Mekonnen Moliso (19920393)

“…Generally, the intervention impact analysis revealed that morbidity rate was significantly decreased (p = 0.009) in intervention years (6.31% in 2018 to 3.02% in 2021) and that herd health interventions provide an added value.…”

Data_Sheet_1_Evaluating a computer-based body exposure paradigm for the treatment of body image disturbance in adolescent Anorexia Nervosa: effects on the attentional bias and emot... by Lena Sasse (20434616)

“…</p>Conclusions<p>While the existence of an AB was demonstrated, the carried-out body exposures were neither sufficient to reduce the AB nor the psychopathology; nevertheless, a significant decrease in anxiety levels showed the usefulness of the exposure sessions. …”