Supplementary file 1_Amomum tsao-ko Crevost et Lemarie extract targets the gut-liver axis to combat atherosclerosis in ApoE−/− mice.docx by Qianqian Wang (494839)

“…Serological tests confirmed T-K’s ability to decrease the total serum cholesterol and low-density lipoprotein cholesterol levels. …”

Supplementary file 1_Full-dose versus reduced-dose comparison of direct oral anticoagulants for extended treatment of venous thromboembolism: a systematic review and meta-analysis... by Renshu Zhang (22775495)

“…</p>Conclusion<p>Reduced-dose DOACs were associated with a significant decrease in the risk of major bleeding/CRNMB compared with full-dose DOACs, but were not associated with a significant increase in the risk of recurrent VTE. …”

Image 5_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”

Image 3_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”

Supplementary file 1_Phase angle as a predictor of prolonged length of hospital stay and adverse outcomes in elderly medical inpatients: a retrospective cohort study.docx by Jia Liu (41593)

“…Adverse event rates across the PhA tertiles (T1–T3) were 32.9%, 18.6%, and 5.6%, respectively, indicating a significant decrease in event incidence as PhA values increased. …”

Data Sheet 1_Global, regional, and national burden of acute glomerulonephritis in children and adolescents: 1990–2021 analysis and future projections.docx by Ming Liu (105953)

“…</p>Results<p>From 1990 to 2021, the global burden of AGN among children and adolescents remained significantly high. In 2021, there were approximately 170,584 new cases, representing a decrease compared to earlier years, with an age-standardized incidence rate (ASIR) of 6.47 per 100,000 (95% UI: 4.79–8.45). …”

<b>Characterizing the role of PP2AB'' family subunits in mechanical stress response and plant development through calcium and ABA signaling in </b><b><i>Arabidopsis thaliana</i></b... by Hyuk Sung Yoon (19985262)

“…Transcriptome analysis showed a significant decrease in the expression of <i>CYP707A3</i>, a gene potentially targeted by VIP1 that regulates abscisic acid (ABA) catabolism, in the <i>atb''αβγδ</i> mutant compared to wild type leaves. …”

Data Sheet 3_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Table 2_The impact of the herd health interventions in small ruminants in low input production systems in Ethiopia.docx by Mesfin Mekonnen Moliso (19920393)

“…Generally, the intervention impact analysis revealed that morbidity rate was significantly decreased (p = 0.009) in intervention years (6.31% in 2018 to 3.02% in 2021) and that herd health interventions provide an added value.…”

DataSheet2_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction by Yangyi Huang (11859382)

“…</p> <p>The EOZ continued decreasing following hyperopic KLEx. A larger TZ and POZ would result in a larger postoperative EOZ.…”

Supplementary Material for: Global, Regional, and National Burden of Neonatal Encephalopathy Due to Birth Asphyxia and Trauma, Its Attributable Risk Factors, 1990-2021: Results fro... by figshare admin karger (2628495)

“…Low SDI regions experienced a substantial 112.9% increase in NEBAT cases, while high-middle SDI regions witnessed a significant 34.8% decrease. Although mortality rates declined across all SDI regions, the low SDI region had the smallest decline. …”

<b>ART does not correct plasma virome and cytokine dysregulations induced by HIV-1</b> by Yingying Ma (18762652)

“…Notably, most cytokines dysregulated were not fully restored by ART, with abnormal levels of IL-10, GM-CSF, VEGF, and eotaxin, and a significantly increased level of plasma I-FABP. Anelloviruses showed significantly negative correlations with other commensal viruses except HPgV-1, but had positive corrections with several anti-inflammatory and Th1 cytokines.…”

Image 1_Emphysema-related mortality rates in the U.S. from 1999 to 2022.pdf by Alexandra Brown (225908)

“…</p>Discussion<p>Emphysema-related deaths in the United States decreased overall between 1999 and 2022, likely a result of a greater emphasis on health education concerning the significant dangers of smoking and policy changes that made cigarettes less accessible and less affordable, and more available access to resources and support networks.…”

Secondary and tertiary outcomes. by Maram Khaled (14642937)

“…Primary outcome is pain intensity with movement (elicited by asking the patient to move from supine to sitting position) using 0–10 Numerical Rating Scale (0 = no pain, 10 = worst possible pain).</p><p>Significance</p><p>The results of this study may result in improved pain control, maternal satisfaction and wound healing; decrease the use of perioperative opioids; potentially decrease the incidence of postpartum depression and persistent pain; and overall lead to better postoperative outcomes thereby decreasing healthcare costs.…”

CONSORT flow diagram. by Maram Khaled (14642937)

“…Primary outcome is pain intensity with movement (elicited by asking the patient to move from supine to sitting position) using 0–10 Numerical Rating Scale (0 = no pain, 10 = worst possible pain).</p><p>Significance</p><p>The results of this study may result in improved pain control, maternal satisfaction and wound healing; decrease the use of perioperative opioids; potentially decrease the incidence of postpartum depression and persistent pain; and overall lead to better postoperative outcomes thereby decreasing healthcare costs.…”

Treatment consequence and adverse events of cyclin-dependent kinase 4/6 inhibitors on patients with hormone receptor-positive, HER2-negative metastatic breast cancer: a systematic... by Hsiang-Ying Wu (22212274)

“…This meta-analysis found that HR(+)/HER2(−) metastatic breast cancer treated with CDK4/6 inhibitors plus endocrine therapy can significantly improve progression-free survival(PFS) (HR: 0.55; <i>p</i> < 0.001), overall survival (OS) (HR: 0.79; <i>p</i> < 0.001), objective response rate (RR = 1.50; <i>p</i> < 0.001), clinical benefit rate (RR = 1.18; <i>p</i> < 0.001) and decrease progressive disease rate (RR = 0.49; <i>p</i> < 0.001). …”

Data_ALL by Myriam Campos Aguilar (15856298)

“…<p dir="ltr">Metabolic syndrome (MetS) is a clinical condition characterized by multiple risk Q8 factors that significantly increase the likelihood of developing cardiovascular diseases and type 2 diabetes. …”

Supplementary Material for: Serendipitous Discovery of Lipemia Retinalis in a Premature Infant: A Case Report by Nikkhah H. (17051934)

“…Introduction Lipemia retinalis (LR) is a rare ocular condition characterized by a creamy white appearance of the retinal vessels, which is indicative of significantly elevated serum triglyceride (TG) levels. …”

Osseointegration of an innovative functionally gradient biomimetic scaffold based on Voronoi-Tessellation for the design of orthopaedic implants by Yuzhu Wang (845659)

“…<p>The geometry and pore size of porous structures have a significant impact on osseointegration in orthopaedic implant design. …”