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level decrease » levels decreased (Expand Search), level increased (Expand Search), teer decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
level decrease » levels decreased (Expand Search), level increased (Expand Search), teer decrease (Expand Search)
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18501
Data Sheet 1_Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning.zip
Published 2025“…Based on machine learning-selected indicators, antiviral therapy and The HBV DNA copy number showed a significant correlation with both the occurrence and severity of irAEs. …”
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18502
Analysis of potential targets of 20S-protopanaxadiol on diabetic nephropathy based on network pharmacology, molecular docking, and experimental validation
Published 2025“…Furthermore, PPD decreased the expression of TGF-β1, p-Smad3, and Smad4 in high glucose-induced HK-2 cells. …”
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18503
Table 12_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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18504
Table 1_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…</p>Conclusions<p>While significant progress has been made in reducing the global burden of pediatric IE, major geographic and socio-demographic inequalities persist. …”
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18505
Image1_Chaihu Shugan powder restores fatty acid synthesis to alleviate insulin resistance in metabolic syndrome by regulating the LXRα/SREBP-1 signaling pathway.TIF
Published 2024“…Background<p>Metabolic syndrome (MS) is a significant risk factor for cardiovascular and cerebrovascular diseases, primarily driven by insulin resistance (IR). …”
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18506
Table 3_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…</p>Conclusions<p>While significant progress has been made in reducing the global burden of pediatric IE, major geographic and socio-demographic inequalities persist. …”
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18507
Image 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …”
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18508
Data Sheet 1_Reconstructing Holocene centennial cooling events: synthesized temperature changes, chronology, and forcing in the Northern Hemisphere.docx
Published 2024“…The Holocene Thermal Maximum (HTM) happened between HCCEs 5 and 4a and was interrupted by HCCE 4c and 4b, coeval, with a significant southward shift of the ITCZ, likely related to cooling in the tropical zone. …”
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18509
Image 3_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …”
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18510
3D Nanoscale Structures of Hydrated Polyamide Desalination Membranes Revealed by Cryogenic Transmission Electron Microscopy Tomography
Published 2025“…Our findings reveal significant morphological differences between hydrated and dry membranes, resulting in variations in key structural parameters that impact performance. …”
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18511
Table 3_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …”
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18512
Supplementary Material for: Genetical predicted causal relationship between gut microbiota and different types of kidney diseases
Published 2025“…No significant pleiotropy or heterogeneity was identified. …”
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18513
Table 9_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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18514
Data Sheet 3_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf
Published 2025“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
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18515
Image 1_Association between controlling nutritional status score and mortality in older patients with dysphagia in Japan: a retrospective cohort study.tif
Published 2025“…Median survival durations decreased progressively: 716 days (mild), 362 days (moderate), and 106 days (severe). …”
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18516
Catalytic CO<sub>2</sub> Capture Performance of a MEA-EAE-DEEA Trisolvent in a Hot Silicon Oil-Based Pilot Plant
Published 2024“…Under the optimized conditions, the heat duty was decreased from 3.0 to 2.46 GJ/t CO<sub>2</sub> over the noncatalytic benchmark.…”
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18517
Table 5_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …”
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18518
Data Sheet 3_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip
Published 2025“…With 0 and 15 μg/m<sup>3</sup> taken as the reference concentrations, all-cause mortality decreased by 47.41% (233,173 cases) and 65.55% (240,448 cases), respectively. …”
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18519
Data Sheet 1_Impact of early enteral nutrition on the prognosis of mechanically ventilated patients with chronic obstructive pulmonary disease: a retrospective cohort study based o...
Published 2025“…</p>Conclusion<p>Although early EN did not significantly improve overall mortality, it effectively decreased ventilation duration and hospital stays and demonstrated potential survival benefits for patients with better oxygenation. …”
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18520
Data Sheet 1_An analysis of the global burden of childhood and adolescent asthma attributable to high BMI: 1990–2021.pdf
Published 2025“…Statistical analysis showed a significant correlation between SDI and asthma burden (P < 0.001), with the overall disease burden increasing as SDI rose. …”