<b>Inhibition of NLRP3 Inflammasome Activation by Xylitol Attenuates </b><b><i>Fusobacterium nucleatum</i></b><b>-Driven Preterm Birth</b> by Eui-jeong Noh (21699797)

“…Xylitol also exhibited antimicrobial effects against <i>F. nucleatum</i> within the uterine and placental tissues, correlating with decreased inflammasome activity. Notably, IL-1β levels in the placental labyrinth zone were significantly reduced in xylitol-treated, <i>F. nucleatum</i>-infected mice.…”

Data Sheet 1_Integration of transcriptome and phytohormone analyses reveals antagonistic interactions between jasmonate and auxin signaling pathways in rice (Oryza sativa L.).docx by Xiaoying Wu (695037)

“…Importantly, MeJA application significantly influenced auxin biosynthesis and orchestrated large-scale changes in transcriptional regulation of L-tryptophan (Trp) biosynthesis, as well as indole-3-acetic acid (IAA) biosynthesis, catabolism, signaling transduction, and transport in rice leaves and roots, leading to notably decreased IAA in the leaves and roots, but increased levels of indole-3-carboxylic acid (ICA) and indole-3-carboxaldehyde (ICAld) in the leaves. …”

<b>Differential Myopathic and Transcriptomic Changes in Soleus and Gastrocnemius Muscles in a Novel Chronic Hindlimb Ischemia Rat Model Induced by Endovascular Catheter Occlusion</... by Hanjun Wang (21595280)

“…Histological analysis revealed that IFCO significantly increased levels of fibrosis and decreased myofiber cross-sectional area, in the soleus only. …”

Data Sheet 1_Impaired SREBP1-mediated regulation of lipid metabolism promotes inflammation in chronic endometritis.pdf by Shigeru Matsuda (17748717)

“…Importantly, EPA-containing phospholipids were also decreased in endometrial tissue from human CE patients. …”

Supplementary Material for: The effectiveness of regionalization of perinatal care and specific facility-based interventions: A systematic review by Ali A.A. (19754238)

“…Results: Implementation of regionalization programs significantly decreased maternal and perinatal mortality. …”

Table 1_Synergistic effects of multi-enzyme supplementation on nutrient digestion and absorption in the foregut and hindgut.docx by Fangyuan Chen (2147119)

“…In vitro results demonstrated that MCPC increased the phosphorus and reducing sugar levels in the supernatant during enzymatic hydrolysis. …”

Image1_Neutrophil-activating protein in Bacillus spores inhibits casein allergy via TLR2 signaling.jpeg by Zhuwei Liang (8762337)

“…Interleukin-12 and interferon-gamma levels increased, whereas serum CAS-specific IgG1 and IgE levels decreased. …”

The prognostic value of the neutrophil-percentage-to-albumin ratio for all-cause and cardiovascular mortality in chronic kidney disease stages G3a to G5: insights from NHANES 2003–... by Jialing Rao (20354623)

“…High levels NPAR exhibited a significantly elevated risk of both all-cause and CVD mortality in the fully adjusted model. …”

Table 1_Organic fertilizer in combination with zeolite enhanced maize yield with lower greenhouse gas emissions in sandy loam soil in North China.docx by Xuexia Wang (3701098)

“…Compared with SF, the levels of available potassium and phosphorus content, dissolved organic carbon content, soil β-glucosidase activity, and microbial biomass carbon and nitrogen concentration in the ZOF treatment were significantly higher by 7.34, 8.90, 19.48, 9.20, 8.42, and 11.29%, respectively; however, soil NH₄⁺-N and NO₃⁻-N were significantly lower by 9.08 and 9.30%, respectively. …”

Table 1_Exploring the alleviating effects of Bifidobacterium metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis.docx by Hongmei Zhao (250090)

“…</p>Results<p>In vivo findings indicated that, in comparison to CBX group (Control group without antibiotic treatment), NAFLD/CBX group (NAFLD group without antibiotic administration) and NAFLD/ABX group (NAFLD group with antibiotic administration) exhibited increased liver-to-body weight ratio, higher lipid droplet accumulation, aggravated liver histopathological damage, and elevated levels of AST (Aspartate Aminotransferase), ALT (Alanine Aminotransferase), TC (Total Cholesterol), TG (Triglycerides), LDL-C (Low-Density Lipoprotein Cholesterol), IL-6 (Interleukin-6), TNF-α (Tumor Necrosis Factor-alpha), IL-1β (Interleukin-1 beta), and NLRP3-related molecules, while HDL-C (High-Density Lipoprotein Cholesterol) levels significantly decreased. …”

Human Wharton’s jelly-derived mesenchymal stem cells (hWJ-MSCs) and recombinant growth regulated oncogene-alpha (GRO-α) inhibit necroptosis in an mdx mice model. by Sang Eon Park (11243760)

“…The CK levels were significantly decreased in the hWJ-MSC-injected and GRO-α-treated groups. …”

Relative expression of hub genes. by Ziyang Liu (242055)

“…<p>qPCR results showed that the expression of EXT1 and FMOD was significantly upregulated in DKD mouse(p < 0.01), while SBSPON expression decreased (p < 0.05) and SPTB expression decreased significantly (p < 0.01).…”

Data Sheet 3_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Data Sheet 1_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

<b>SZC-6</b><b> Promotes Diabetic Wound Healing in Mice by Modulating M1/M2 Macrophage Ratio and Inhibiting MyD88/NF-κB Pathway</b> by 昂 轩 (20139579)

“…We also found that SZC-6 significantly reduced MyD88, p-IκBα, and p-P65 protein levels and inhibited the nuclear translocation of P65 in LPS-treated cells. …”

Data Sheet 4_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Data Sheet 1_The CaSBP11 gene functions as a negative regulator in pepper drought stress.doc by Huai-Xia Zhang (8493453)

“…Conversely, overexpression of CaSBP11 in Nicotiana benthamiana decreased drought tolerance, with CaSBP11-overexpressing plants showing reduced ABA sensitivity, lower stomatal aperture and ABA levels, and increased stomatal density and ROS production compared to wild-type plants. …”

Table 1_Predicting psychiatric risk: IgG N-glycosylation traits as biomarkers for mental health.xls by Yinchun Lv (18181816)

“…</p>Results<p>In the Psychiatric Genomics Consortium (PGC) database, genetically predicted IGP7 showed a protective role in schizophrenia (SCZ), major depressive disorder (MDD), and bipolar disorder (BIP), while elevated IGP34, and IGP57 increased SCZ risk. High levels of IGP21 were associated with an increased risk of post-traumatic stress disorder (PTSD), while elevated levels of IGP22 exhibited a causal association with a decreased risk of attention-deficit/hyperactivity disorder (ADHD). …”

Supplementary file 1_Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice.d... by Yong Lai (4104235)

“…Also, compared with the NR group, DIPY increasing the relative abundance of Parasutterella and Blautia, increasing the production of acetic acid (p < 0.001), and decreasing the levels of LPS, MCP-1, TNF-α, and IL-6 (p < 0.05) which attenuating inflammatory responses.…”

Supplementary Material for: Gut microbiome composition and one-year survival outcomes among patients with reduced ejection fraction heart failure by figshare admin karger (2628495)

“…Decreased levels of Prevotella, F. prausnitzii, Firmicutes, and Bacteroides, as well as a lower Firmicutes/Bacteroidetes (F/B) ratio, were notable in HFrEF patients, with specific taxa correlating with clinical features like ascites and vitamin D levels. …”