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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
level increased » levels increased (Expand Search), levels decreased (Expand Search), gene increased (Expand Search)
level decrease » levels decreased (Expand Search), teer decrease (Expand Search), level disease (Expand Search)
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2421
Cascade Nanozyme-Loaded Sprayable Hydrogels for Fibroblast Rejuvenation and Diabetic Wound Regeneration
Published 2025“…In a bacterial-infected diabetic rat skin wound model, the zcgG group demonstrated substantially reduced inflammatory levels, a 68% decrease in AGEs, and a 1.9-fold increase in collagen deposition compared to blank controls. …”
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2422
Dynamic changes in mRNA stability.
Published 2025“…<b>(D)</b> GO analysis showing the enriched biological processes for mRNAs with increased (left) or decreased (right) stability in 6 hours of LPS treatment. …”
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2423
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2424
Changes in the separation and spread of evidence distributions induced by energy, contrast, and variability manipulations.
Published 2024“…For all experiments, increasing energy and contrast levels increases the separation between the two stimulus categories, while increasing variability decreases the separability between the two stimulus categories. …”
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2425
FSA inhibits MaAKT1 channels through <i>S</i>-glutathionylation.
Published 2025“…Representative whole-cell current traces and summary of the preventive effect of DTT (5 mM) in the pipette on FSA-induced MaAKT1 inhibition (n = 3). Ns, not significant compared with control group. (<b>C</b>) FSA treatment decreases intracellular GSH level (left), increases GSSG level (middle), and reduces GSH/GSSG ratio (right) (n = 3). …”
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2426
Table 1_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx
Published 2025“…Furthermore, our in vivo data demonstrated that sepsis (induced by intraperitoneal bacterial infection) led to a significant decrease in serum 25(OH)D levels.</p>…”
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2427
Table 7_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx
Published 2025“…Furthermore, our in vivo data demonstrated that sepsis (induced by intraperitoneal bacterial infection) led to a significant decrease in serum 25(OH)D levels.</p>…”
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2428
Table 3_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx
Published 2025“…Furthermore, our in vivo data demonstrated that sepsis (induced by intraperitoneal bacterial infection) led to a significant decrease in serum 25(OH)D levels.</p>…”
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2429
Table 6_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx
Published 2025“…Furthermore, our in vivo data demonstrated that sepsis (induced by intraperitoneal bacterial infection) led to a significant decrease in serum 25(OH)D levels.</p>…”
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2430
Table 2_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx
Published 2025“…Furthermore, our in vivo data demonstrated that sepsis (induced by intraperitoneal bacterial infection) led to a significant decrease in serum 25(OH)D levels.</p>…”
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2431
Table 5_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx
Published 2025“…Furthermore, our in vivo data demonstrated that sepsis (induced by intraperitoneal bacterial infection) led to a significant decrease in serum 25(OH)D levels.</p>…”
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2432
Table 4_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx
Published 2025“…Furthermore, our in vivo data demonstrated that sepsis (induced by intraperitoneal bacterial infection) led to a significant decrease in serum 25(OH)D levels.</p>…”
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2433
Image 2_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg
Published 2025“…Gavage with F.n, P.g or the biofilm consortium (BF group) induced intestinal barrier disruption and elevated pro-inflammatory cytokines levels. PCR indicated a significant increase in the expression of IL-1β, TNF-α, B220, F4/80, and NOS2 in the P group (P < 0.001), while Arg-1 expression exhibited a significant decrease (P < 0.01). …”
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2434
Image 3_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg
Published 2025“…Gavage with F.n, P.g or the biofilm consortium (BF group) induced intestinal barrier disruption and elevated pro-inflammatory cytokines levels. PCR indicated a significant increase in the expression of IL-1β, TNF-α, B220, F4/80, and NOS2 in the P group (P < 0.001), while Arg-1 expression exhibited a significant decrease (P < 0.01). …”
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2435
Image 1_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg
Published 2025“…Gavage with F.n, P.g or the biofilm consortium (BF group) induced intestinal barrier disruption and elevated pro-inflammatory cytokines levels. PCR indicated a significant increase in the expression of IL-1β, TNF-α, B220, F4/80, and NOS2 in the P group (P < 0.001), while Arg-1 expression exhibited a significant decrease (P < 0.01). …”
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2436
Image 4_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg
Published 2025“…Gavage with F.n, P.g or the biofilm consortium (BF group) induced intestinal barrier disruption and elevated pro-inflammatory cytokines levels. PCR indicated a significant increase in the expression of IL-1β, TNF-α, B220, F4/80, and NOS2 in the P group (P < 0.001), while Arg-1 expression exhibited a significant decrease (P < 0.01). …”
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2437
Data Sheet 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.pdf
Published 2025“…Meanwhile, HIRI can significantly increase the expression of genes related to liver injury and inflammation, while SEN pretreatment can lead to a concentration-dependent decrease in these genes. …”
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2438
Table 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.xls
Published 2025“…Meanwhile, HIRI can significantly increase the expression of genes related to liver injury and inflammation, while SEN pretreatment can lead to a concentration-dependent decrease in these genes. …”
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2439
Table 1_Impact of China’s National Volume-Based Procurement policy exclusively for insulin on the volume, expenditure and price: an interrupted time series analysis in Guangdong Pr...
Published 2025“…Subgroup analysis demonstrated divergent trends between insulin generations, with non-significant decrease in second-generation insulin and increase in third-generation insulin procurement in long-term trend. …”
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2440
Data Sheet 2_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio...
Published 2025“…The signaling pathways regulating the antidepressant properties of OGF were obtained by transcriptome sequencing analysis and validated at the protein level.</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”