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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
level increased » levels increased (Expand Search), levels decreased (Expand Search), gene increased (Expand Search)
level decrease » levels decreased (Expand Search), teer decrease (Expand Search), level disease (Expand Search)
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2441
Data Sheet 1_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio...
Published 2025“…The signaling pathways regulating the antidepressant properties of OGF were obtained by transcriptome sequencing analysis and validated at the protein level.</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”
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2442
Table 1_fNIRS, EEG, ECG, and GSR reveal an effect of complex, dynamically changing environments on cognitive load, affective state, and performance, but not physiological stress.xl...
Published 2025“…Furthermore, we found a temporal effect of workload in the constant workload conditions, evidenced by increased fNIRS activation (HbO increase and HbR decrease), and mental fatigue measured by EEG (Delta power increase). …”
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2443
Reversibility of interannual tree growth variability in southern boreal forest
Published 2025“…During the subsequent period (2007−2018), the interannual growth variability decreased rapidly (−0.04 year−1) to the level in the early 1980s, while the annual growth rate exhibited no significant trend. …”
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2444
Data Sheet 1_fNIRS, EEG, ECG, and GSR reveal an effect of complex, dynamically changing environments on cognitive load, affective state, and performance, but not physiological stre...
Published 2025“…Furthermore, we found a temporal effect of workload in the constant workload conditions, evidenced by increased fNIRS activation (HbO increase and HbR decrease), and mental fatigue measured by EEG (Delta power increase). …”
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2445
Figure 4 from Photoacoustic Tomography Detects Response and Resistance to Bevacizumab in Breast Cancer Mouse Models
Published 2025“…<b>C,</b> Conversely, the Bev-R group trend toward a significant decrease in SO<sub>2</sub><sup>MSOT</sup>, with no significant change in normalized THb observed. …”
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2446
Image 1_Hyperglycemia causes differential change in macrophage population in the lacrimal gland, conjunctiva and cornea.tif
Published 2024“…Further, hyperglycemia did not cause any notable changes in macrophage phenotypes, their activation status or the expression of IL-1β, TNF-α, IFN-γ, CCL2 except in the cornea where an increase in the cytokine levels was noted after 7 days of hyperglycemia</p>Conclusion<p>Our data shows that diabetes-associated hyperglycemia can cause a significant decrease in microphage population with changing their plasticity or activation status in lacrimal gland, conjunctiva and cornea but the kinetics of decrease and recovery show differential pattern specific for each tissue.…”
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2447
Supplementary Material for: The Impact of Changes in Fasting Plasma Glucose Before and After Heart Failure Diagnosis on All-Cause Mortality
Published 2025“…Methods: A prospective cohort study based on the Kailuan study included 3533 Patients with HF after excluding those with prior HF, malignancies, or missing FPG data. FPG levels were measured before and after HF diagnosis and categorized into five groups: significant decrease (Q1), mild decrease (Q2), stable (Q3), mild increase (Q4), and significant increase (Q5). …”
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2448
Data Sheet 1_Large scale atmospheric conditions favoring storm surges in the North and Baltic Seas and possible future changes.docx
Published 2025“…<p>Climate change will not only cause significant sea level rise but is likely to also change the large-scale atmospheric circulation. …”
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2449
Table 1_The impact of public participatory environmental regulation on carbon emission intensity: a policy text analysis.docx
Published 2025“…The findings reveal that: (1) public participatory environmental regulation significantly reduces carbon emission intensity; specifically, baseline regression results indicate that a one-unit increase in public participatory environmental regulation intensity leads to a 0.05 unit decrease in carbon emission intensity, significant at the 1% level; (2) mediation analysis demonstrates that public environmental participation serves as a significant intermediary between environmental regulation and carbon emission reduction; (3) heterogeneity analysis indicates that official characteristics significantly moderate policy effectiveness, with regulations implemented by non-local, shorter-tenured, and less-educated officials showing stronger inhibitory effects on carbon emissions compared to their counterparts. …”
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2450
DataSheet1_Elucidation of pineapple softening based on cell wall polysaccharides degradation during storage.docx
Published 2024“…However, the content of 4 M KOH-soluble hemicellulose (HC2) decreased and then returned to the initial level. Furthermore, WSP, ASP, and HC1 showed an increment in the content of low molecular weight polymers while a decline in the high molecular weight polymers throughout softening, and not significant change in the contents of different molecular polymers of HC2 was observed. …”
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2451
DataSheet1_Elucidation of pineapple softening based on cell wall polysaccharides degradation during storage.docx
Published 2024“…However, the content of 4 M KOH-soluble hemicellulose (HC2) decreased and then returned to the initial level. Furthermore, WSP, ASP, and HC1 showed an increment in the content of low molecular weight polymers while a decline in the high molecular weight polymers throughout softening, and not significant change in the contents of different molecular polymers of HC2 was observed. …”
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2452
Supplementary Material for: Characteristics of asthmatic patients with IL18R1 differential expression in induced sputum
Published 2025“…Conclusions: IL18R1 level in induced sputum was increased. IL18R1low and IL18R1high asthma subgroups had different clinical features and responses to ICS treatment. …”
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2453
<b>Mechanisms of Modified Qinghao Biejia Decoction in Reversing Drug Resistance in K562/ADM Cells via Autophagy Inhibition</b> (Supplementar data).xlsx
Published 2025“…The mean fluorescence intensity of MDC, which measures the level of autophagic vacuoles, was significantly decreased in the FG and FG+3MA groups, which implies a decrease in autophagic flux. …”
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2454
Data Sheet 1_Analysis and comparison of the trends in burden of spinal cord injury in China and worldwide from 1990 to 2021: an analysis of the global burden of disease study 2021....
Published 2025“…Joinpoint analysis revealed a significant decrease in the APC of the age-standardized incidence rate (ASIR) from 1990 to 2011 (APC = −0.98, p < 0.05), followed by a notable increase from 2011 to 2021 (APC = 2.05, p < 0.05). …”
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2455
Data Sheet 2_Analysis and comparison of the trends in burden of spinal cord injury in China and worldwide from 1990 to 2021: an analysis of the global burden of disease study 2021....
Published 2025“…Joinpoint analysis revealed a significant decrease in the APC of the age-standardized incidence rate (ASIR) from 1990 to 2011 (APC = −0.98, p < 0.05), followed by a notable increase from 2011 to 2021 (APC = 2.05, p < 0.05). …”
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2456
Table 1_Association between neutrophil percentage-to-albumin ratio and breast cancer in adult women in the US: findings from the NHANES.docx
Published 2025“…The significance of traits was assessed using mean decrease accuracy (MDA) and mean decrease impurity (MDI). …”
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2457
Image 4_Structures and determinants of soil microbiomes along a steep elevation gradient in Southwest China.jpeg
Published 2025“…Soil bacterial chemoheterotrophy was the dominant lifestyle and was predicted to decrease with increasing elevation. In terms of fungal lifestyles, saprophytic and symbiotic fungi were the dominant functional communities but their relative abundance was negatively correlated with increasing elevation. …”
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2458
Image 3_Structures and determinants of soil microbiomes along a steep elevation gradient in Southwest China.jpeg
Published 2025“…Soil bacterial chemoheterotrophy was the dominant lifestyle and was predicted to decrease with increasing elevation. In terms of fungal lifestyles, saprophytic and symbiotic fungi were the dominant functional communities but their relative abundance was negatively correlated with increasing elevation. …”
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2459
Image 5_Structures and determinants of soil microbiomes along a steep elevation gradient in Southwest China.jpeg
Published 2025“…Soil bacterial chemoheterotrophy was the dominant lifestyle and was predicted to decrease with increasing elevation. In terms of fungal lifestyles, saprophytic and symbiotic fungi were the dominant functional communities but their relative abundance was negatively correlated with increasing elevation. …”
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2460
Table 1_Structures and determinants of soil microbiomes along a steep elevation gradient in Southwest China.xlsx
Published 2025“…Soil bacterial chemoheterotrophy was the dominant lifestyle and was predicted to decrease with increasing elevation. In terms of fungal lifestyles, saprophytic and symbiotic fungi were the dominant functional communities but their relative abundance was negatively correlated with increasing elevation. …”