Data Sheet 2_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…</p>Results<p>Untargeted metabolomics revealed that, after SY009 treatment, there were differences in metabolic pathways, including primary bile acid biosynthesis; biosynthesis of unsaturated fatty acid; steroid hormone biosynthesis; purine metabolism; phenylalanine, tyrosine and tryptophan biosynthesis. In particular, the increase in bile acid-related metabolites in the 2 mg BID group was significantly greater than that in the placebo group, and unsaturated fatty acid-related metabolites decreased in both the 2 mg BID group and the placebo group, but there was no significant difference between the two groups. …”

Data Sheet 1_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…</p>Results<p>Untargeted metabolomics revealed that, after SY009 treatment, there were differences in metabolic pathways, including primary bile acid biosynthesis; biosynthesis of unsaturated fatty acid; steroid hormone biosynthesis; purine metabolism; phenylalanine, tyrosine and tryptophan biosynthesis. In particular, the increase in bile acid-related metabolites in the 2 mg BID group was significantly greater than that in the placebo group, and unsaturated fatty acid-related metabolites decreased in both the 2 mg BID group and the placebo group, but there was no significant difference between the two groups. …”

Table 2_Factors influencing bone mineral density in hyperparathyroidism phenotypes: a prospective study.xlsx by Margot Giocondo (21435500)

“…This condition is characterized by inappropriately elevated parathyroid hormone (PTH) levels relative to serum calcium levels, leading to high bone turnover and decreased bone mineral density (BMD). …”

Table 1_Factors influencing bone mineral density in hyperparathyroidism phenotypes: a prospective study.xlsx by Margot Giocondo (21435500)

“…This condition is characterized by inappropriately elevated parathyroid hormone (PTH) levels relative to serum calcium levels, leading to high bone turnover and decreased bone mineral density (BMD). …”

Loss of H2A.Z from transcription start sites was correlated with, but not required for, HU-induced gene activation. by Hilary T. Brewis (11798006)

“…There was overlap found in all four groups: 1) genes that had increased mRNA expression and H2A.Z enrichment at their TSS in the HU-treated condition, 2) mRNA expression increased, while H2A.Z enrichment decreased, 3) mRNA expression decreased, while H2A.Z enrichment increased, and 4) genes where mRNA expression and H2A.Z enrichment at the TSS decreased after HU exposure. …”

Table 2_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx by Cindy E. Frias (20899853)

“…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…”

Table 1_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx by Cindy E. Frias (20899853)

“…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…”

Table 3_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx by Cindy E. Frias (20899853)

“…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…”

Data_Sheet_1_Respiratory pathogen analysis in pediatric inpatients unraveled the infection pattern of Mycoplasma pneumoniae post the COVID-19 pandemic.docx by Qihong Chen (541270)

“…Under NPIs, most respiratory infections declined compared to pre-pandemic levels, rebounding by 69.64% in 2023. While the infection rate of common respiratory pathogens decreased, cases of respiratory syncytial virus increased during the period of extensive NPI implementation. …”

Table 1_S-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial.docx by Vineetha Vijayakumar (17064126)

“…</p>Results<p>Crow’s feet wrinkle roughness decreased by 5.6% in the Novasoy®400 group versus a 1.6% increase in the placebo group, this difference was not statistically significant. …”

Table 1_Differential resilience of chickpea’s reproductive organs to cold stress across developmental stages: insights into antioxidant strategies for enhanced fertility.docx by Deeksha Padhiar (21010250)

“…<p>Chickpea is highly sensitive to cold stress during its reproductive stages, leading to significant reductions in potential pod formation due to decreased reproductive success. …”

Table 2_Differential resilience of chickpea’s reproductive organs to cold stress across developmental stages: insights into antioxidant strategies for enhanced fertility.docx by Deeksha Padhiar (21010250)

“…<p>Chickpea is highly sensitive to cold stress during its reproductive stages, leading to significant reductions in potential pod formation due to decreased reproductive success. …”

Supplemental file for Training alters cytokine and soluble receptor responses by Jeremy Ducharme (20174820)

“…Instead, pro-inflammatory cytokine levels remained close to baseline, while the levels of anti-inflammatory cytokines IL-10 and IL-1Ra increased. …”

<b>Impact of Magnitude and Duration of Soil Warming on Bacterial Communities and Nitrogen Cycling in the Rhizosphere and Bulk Soil of Subarctic Grasslands</b> by Arun Kumar Devarajan (21358373)

“…The results revealed that bacterial abundances showed significant warming thresholds at lower temperature increases in the rhizospheres (+0.83℃ in GN, +1.34℃ in GO) compared to bulk soils (+1.42℃ in GN; no threshold detected in GO), with abundances declining below these thresholds, indicating greater warming sensitivity of rhizosphere communities. …”

Table 1_Effects of quantitative marinating on meat quality, biogenic amines, and flavor compounds in crayfish meat.docx by Kelang Kang (12911015)

“…Headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) identified 31 compounds, with QM having more volatile compounds such as anethole, linalool, and 1-octanol than SG. The levels of biogenic amines of tryptamine, phenethylamine, and histamine in QM decreased significantly compared with SG (P < 0.05). …”

Data Sheet 1_Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.xlsx by Gabriela Gonzales (19756103)

“…Inflammatory markers IFN-γ, IL-4, and IL-1β were elevated in dexamethasone-ETT groups at 3 days, then decreased by 7 days. Macrophage markers CD86 and CD206 were significantly greater in dexamethasone groups compared to regular ETT groups at 7 days (p = 0.002 and p = 0.0213, respectively). …”

Table 1_Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.xlsx by Gabriela Gonzales (19756103)

“…Inflammatory markers IFN-γ, IL-4, and IL-1β were elevated in dexamethasone-ETT groups at 3 days, then decreased by 7 days. Macrophage markers CD86 and CD206 were significantly greater in dexamethasone groups compared to regular ETT groups at 7 days (p = 0.002 and p = 0.0213, respectively). …”

Data Sheet 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.pdf by Evan Fuini (21224939)

“…Treatment with psilocybin resulted in a significant dose-dependent increase in positive BOLD signal. …”

Table 4_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx by Evan Fuini (21224939)

“…Treatment with psilocybin resulted in a significant dose-dependent increase in positive BOLD signal. …”

Data Sheet 2_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.docx by Evan Fuini (21224939)

“…Treatment with psilocybin resulted in a significant dose-dependent increase in positive BOLD signal. …”