DataSheet1_Clerodendranthus spicatus [Orthosiphon aristatus (Blume) Miq.] maintains uric acid homeostasis via regulating gut microbiota and restrains renal inflammation in hyperuri... by Yang Wang (5921)

“…In addition, C. spicatus modulated gut microbiota and decreased the relative abundance of Bacteroides, Prevotellaceae_UCG-001 and Alistipes, and increased the abundance of Alloprevotella and Lachnospiraceae_NK4A136_group.C.spicatus altered the expression of the renal urate transporter and key enzymes in hepatic urate synthesis, leading to a decrease in serum uric acid levels. …”

Treatment with TCA and S1P2 agonist induces S1PR2 expression and attenuates ROCK1/RHOA expression; inhibition of S1PR2 reverses TCA- or S1P2-mediated effect on ROCK1/RHOA expressio... by Aya Miyagawa-Hayashino (386487)

“…(C) <i>S1PR2</i> mRNA expression was significantly increased with TCA or S1P2 agonist stimulation as compared with the control and significantly reduced after pretreatment with JTE-013, an antagonist of S1PR2. …”

Data Sheet 1_Impact of zero-markup consumable policy and national procurement of coronary stents on hospitalization expenses: an interrupted time series analysis.pdf by Shao-long Wu (1948273)

“…Background<p>After the successful reforms of drug pricing, China has implemented two significant reforms to reduce medical consumables expenses: the elimination of markup on prices (zero-markup policy) and the implementation of centralized procurement of high-value medical consumables (national procurement policy). …”

Supplementary Material for: Trends in the Incidence of Rare Eyelid Malignancies: A SEER-Based Study (2000–2021) by figshare admin karger (2628495)

“…For MCC; NNAR (2,2) model showed IR stability (0.003-0.008), with a slight drop in 2021 (IR = 0.006), and predicted to decrease to 0.01 (95% PI: 0-0.01). For SGC; ARIMA (0,0,0) model demonstrated a decline in IR in 2011 (IR = 0.0192), increase until 2019, then decrease in 2021 (IR = 0.0246), with a predicted 10-year decrease to 0.026 (95% PI: 0.019–0.032). …”

Data Sheet 1_Grassland restoration impacts human-wildlife and social conflicts in the Chyulu Hills, Kenya.docx by Camila I. Donatti (8442690)

“…There was a negative and significant correlation between the area restored in each site and both the number of human-wildlife conflicts and the number of social conflicts, showing that conflicts decrease as restoration increases. …”

Table 1_Disparities in the burden of tuberculosis associated with urbanization across 178 countries and territories: an observational study.docx by Yaping Wang (289641)

“…For MDR-TB, each additional urbanization score was associated with a 1.0% decrease in incidence (RR = 0.990; 95% CI: 0.985–0.996), a 1.1% decrease in prevalence (0.989; 0.984–0.994), and a 0.7% decrease in mortality (0.993; 0.988–0.998). …”

Image 1_Epimedium brevicornu Maxim. extract activates natural killer cells against hepatocellular carcinoma via the cGAS-STING pathway.tif by Lu Liu (171341)

“…Mechanistic studies revealed that EPE promoted IFN-β release in NK cells, significantly increased the phosphorylation levels of STING and IRF3. …”

The in vitro and in vivo effect of a chemokine inhibitor CTCE-9908 in combination with Kynurenine metabolites on tumour adhesion by Danielle Tatchum (16946574)

“…Results showed a statistically significant decrease in the percentage cell number in L-kyn- and CTCE-9908-treated sEnd-2 cells when compared to the vehicle control, suggesting the inhibitory effect of the compounds on adhesion. …”

Table 1_Study on the invitro synergistic susceptibility and biofilm inhibition mechanism of ceftazidime-avibactam combined with aztreonam against carbapenem-resistant Klebsiella pn... by Guangfen Wang (20906201)

“…The qRT-PCR results showed that CZA combined with ATM notably decreased the expression levels of biofilm-related genes Luxs, mrkA, wbbM, pgaA, and wzm in CRKP.…”

Supplementary file 1_Storage damage of cold-stored whole blood in CPDA maintenance fluid during the whole effective storage period.docx by Yingyu He (13877876)

“…On the 28th day of storage, the coagulation activity significantly decreased with the increase of hemolysis markers, indicating that storage damage to active components such as RBCs, platelets, and coagulation factors in CS-WB was ongoing and remarkably developing.…”

Table 1_Microbiological effect of topically applied Weissella cibaria on equine pastern dermatitis.docx by Eva Styková (20507045)

“…The application of the W. cibaria strain was associated with a significant decrease of the genera Staphylococcus, Moraxella, and Rothia in the proliferative group and with a decrease of Streptococcus and Clostridium in both exudative and proliferative groups. …”

Supplementary Material for: Analysis of retinal and choroidal microvasculature in systemic sclerosis using optical coherence tomography angiography: A systematic review and meta-an... by Lohrasbi F. (20017569)

“…Meta-analysis findings revealed a significant decrease in vessel densities in both the superficial and deep capillary plexuses (SCP and DCP) among SSc patients compared to controls. …”

Table1_Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site.docx by Olivia C. Ihedioha (19925886)

“…Background<p>Host-related factors highly regulate the increased circulation of neutrophils during Leishmania infection. …”

Effect of appetite suppressants on head-weaving stereotypy in female rats. by Axl Lopez (21594203)

“…Notably, one subject (cyan dot) showed a considerable decrease in stereotypy levels on the third day, quantified after 100 minutes post-injection. …”

Table 1_Association between oxidative balance score and all-cause and cancer-specific mortality among cancer survivors.pdf by Qingmei Gao (20905781)

“…</p>Conclusion<p>The findings indicate that higher levels of OBS are associated with a decrease in all-cause and cancer-specific mortality among cancer survivors. …”

Prior immunological memory to pertussis toxin affects the avidity development of anti-PT IgG antibodies after acellular pertussis booster vaccination by Aapo Knuutila (12239402)

“…The development of avidity from one month after vaccination to a year after was highly individual, with some participants having either a decrease, an increase or a stagnant level of avidity. …”

Image1_ASC speck serum concentrations, a component of sterile cellular inflammation, are associated with individual cardiopulmonary capacity.JPEG by Alexander Kogel (13296595)

“…However, subgroup analysis revealed a significant increase in circulating ASC specks in athletes with the lowest baseline values (2.37 ± 0.84 vs. 8.43 ± 7.52 ASC specks/µL, p < 0.05). …”

Protective effect of polyphenols from Potentilla anserina L. against in rat myocardial ischemia-reperfusion on injury by Wnt/β-catenin pathway by Jing Li (10611)

“…Treatment of MIRI with PPA resulted in a significant decrease in protein expression levels of Wnt and β-catenin. …”

Image 3_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”

Image 2_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”