Data Sheet 2_Circulating CD8 T cells from patients with mild-to-moderate psoriasis are functionally impaired.docx by Yiqiao Chen (16964252)

“…In contrast, CD69, IFNγ, and Granzyme B were significantly decreased in anti-CD3/CD28-activated CD8 T cell subsets. …”

Table 1_Association of high consumption of soy products with the risk of cognitive impairment and major neurocognitive disorders: a systematic review and dose-response meta-analysi... by Jialin Yu (131558)

“…While an association with increased risk of cognitive impairment was observed, it was not statistically significant. The dose-response meta-analysis indicated that a 1-g per day increase in the consumption of soy and natto demonstrated a correlation with an 8 and 14% decrease in the likelihood of developing major neurocognitive disorder, respectively. …”

Data Sheet 1_The impact of prudent financial policies on the urban–rural household health expenditure disparity: evidence from China.docx by Wenxin Zou (625953)

“…</p>Results<p>The results show that the regulation significantly affects rural households’ medical expenditures (with a 20.5% decrease in guaranteed investment and a 1.3% increase in out-of-pocket payments), but has no significant impact on urban households. …”

Table 2_The effects of oral medroxyprogesterone acetate combined with conjugated equine estrogens on inflammation in postmenopausal women: a systematic review and meta-analysis of... by Jiahui Qiu (7420130)

“…</p>Results<p>MPA/CEE treatment was associated with a significant decrease in CRP levels (WMD = -0.173 mg/dL; 95% CI: -0.25 to -0.10; P < 0.001), particularly among postmenopausal women aged <60 years, trials with MPA doses ≤2.5 mg/day, and those with BMI <25 kg/m². …”

Image 5_Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study.tiff by Owen Griffith (20516501)

“…Speed players, but not non-speed players, demonstrated a significant decrease in functional connectivity in the precuneus from pre- to post-season (p < 0.001).…”

Image 6_Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study.tiff by Owen Griffith (20516501)

“…Speed players, but not non-speed players, demonstrated a significant decrease in functional connectivity in the precuneus from pre- to post-season (p < 0.001).…”

Image 1_Association of high consumption of soy products with the risk of cognitive impairment and major neurocognitive disorders: a systematic review and dose-response meta-analysi... by Jialin Yu (131558)

“…While an association with increased risk of cognitive impairment was observed, it was not statistically significant. The dose-response meta-analysis indicated that a 1-g per day increase in the consumption of soy and natto demonstrated a correlation with an 8 and 14% decrease in the likelihood of developing major neurocognitive disorder, respectively. …”

Table 2_Transcriptomic and metabolomic analysis of carotenoid metabolism and accumulation of carotenoid-derived products in tobacco leaves before and after curing.xlsx by Tao Liu (10785)

“…Significant decrease in carotenoid contents in leaves was observed during the curing process after harvest. …”

多杀性巴氏杆菌流行过程中水平基因转移对其毒力与耐药的影响-附录.xlsx by He Jiao (19924953)

“…Apart from ABC transporter pathways, there were changes in the transcription levels of multiple protease genes. Upon aggregating A0R64_02365 and its significantly impacted gene set, a consistent gene-level difference emerged. …”

Table 1_Effects of Raga music and Chinese five-element on milk production, antioxidant, neuroendocrine, immune, and welfare indicators in dairy cows.docx by Zongjing Cao (21622439)

“…Dairy cows in the music intervention groups displayed significant improvements in serum biochemical parameters, characterized by decreased levels of alanine aminotransferase (ALT) and triglycerides (TG) (p < 0.05), and increased concentrations of glucose (GLU) and serum albumin (ALB) (p < 0.05). …”

Numerical study on crack coalescence mechanism of rock specimens containing double parallel cracks by Wu Junyu (22515272)

“…<p dir="ltr">In rock engineering, the propagation and coalescence of cracks significantly impact the stability of the rock mass. …”

Data Sheet 1_DYRK1A roles in human neural progenitors.docx by Jeremie Courraud (20871932)

“…In addition, DYRK1A-KD led to a reduction in p21 protein levels, despite an increase in the expression of a minor transcript variant for this gene, and a decrease in ERK pathway activation.…”

Image 4_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg by Xiao Li (107004)

“…The transcriptional activity of NRF2 prompted cell ferroptosis because the transfection of miR-936 mimics, GV102-Pim-3-shRNA and GV102-NRF2-shRNA plasmid increased the expression of transferrin receptor 1 (TFR1) and divalent metal transporter 1 (DMT1) but decreased the expression of solute carrier family 7 member 11 (SLC7A11), glutathione peroxidase 4 (GPX4), quinone oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1), thus facilitating the accumulation of intracellular Fe²⁺, lipid peroxides, and reactive oxygen species (ROS) but reducing the glutathione (GSH) level. …”

Image 2_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg by Xiao Li (107004)

“…The transcriptional activity of NRF2 prompted cell ferroptosis because the transfection of miR-936 mimics, GV102-Pim-3-shRNA and GV102-NRF2-shRNA plasmid increased the expression of transferrin receptor 1 (TFR1) and divalent metal transporter 1 (DMT1) but decreased the expression of solute carrier family 7 member 11 (SLC7A11), glutathione peroxidase 4 (GPX4), quinone oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1), thus facilitating the accumulation of intracellular Fe²⁺, lipid peroxides, and reactive oxygen species (ROS) but reducing the glutathione (GSH) level. …”

Image 1_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg by Xiao Li (107004)

“…The transcriptional activity of NRF2 prompted cell ferroptosis because the transfection of miR-936 mimics, GV102-Pim-3-shRNA and GV102-NRF2-shRNA plasmid increased the expression of transferrin receptor 1 (TFR1) and divalent metal transporter 1 (DMT1) but decreased the expression of solute carrier family 7 member 11 (SLC7A11), glutathione peroxidase 4 (GPX4), quinone oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1), thus facilitating the accumulation of intracellular Fe²⁺, lipid peroxides, and reactive oxygen species (ROS) but reducing the glutathione (GSH) level. …”

Image 5_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg by Xiao Li (107004)

“…The transcriptional activity of NRF2 prompted cell ferroptosis because the transfection of miR-936 mimics, GV102-Pim-3-shRNA and GV102-NRF2-shRNA plasmid increased the expression of transferrin receptor 1 (TFR1) and divalent metal transporter 1 (DMT1) but decreased the expression of solute carrier family 7 member 11 (SLC7A11), glutathione peroxidase 4 (GPX4), quinone oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1), thus facilitating the accumulation of intracellular Fe²⁺, lipid peroxides, and reactive oxygen species (ROS) but reducing the glutathione (GSH) level. …”

Table 1_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.docx by Xiao Li (107004)

“…The transcriptional activity of NRF2 prompted cell ferroptosis because the transfection of miR-936 mimics, GV102-Pim-3-shRNA and GV102-NRF2-shRNA plasmid increased the expression of transferrin receptor 1 (TFR1) and divalent metal transporter 1 (DMT1) but decreased the expression of solute carrier family 7 member 11 (SLC7A11), glutathione peroxidase 4 (GPX4), quinone oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1), thus facilitating the accumulation of intracellular Fe²⁺, lipid peroxides, and reactive oxygen species (ROS) but reducing the glutathione (GSH) level. …”

Image 3_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg by Xiao Li (107004)

“…The transcriptional activity of NRF2 prompted cell ferroptosis because the transfection of miR-936 mimics, GV102-Pim-3-shRNA and GV102-NRF2-shRNA plasmid increased the expression of transferrin receptor 1 (TFR1) and divalent metal transporter 1 (DMT1) but decreased the expression of solute carrier family 7 member 11 (SLC7A11), glutathione peroxidase 4 (GPX4), quinone oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1), thus facilitating the accumulation of intracellular Fe²⁺, lipid peroxides, and reactive oxygen species (ROS) but reducing the glutathione (GSH) level. …”

Supplementary file 1_Dietary α-sitosterol mitigates titanium dioxide nanoparticle-induced hemato-immunotoxicity, oxidative stress, and gene expression dysregulation in Oreochromis... by Amany Behairy (22658510)

“…Furthermore, STL significantly decreased elevated serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, urea, and creatinine levels induced by TDNPs, and normalized lipid profiles by reducing total cholesterol, triglycerides, and low-density lipoprotein cholesterol, while elevating high-density lipoprotein cholesterol. …”

Data Sheet 1_Dietary α-sitosterol mitigates titanium dioxide nanoparticle-induced hemato-immunotoxicity, oxidative stress, and gene expression dysregulation in Oreochromis niloticu... by Amany Behairy (22658510)

“…Furthermore, STL significantly decreased elevated serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, urea, and creatinine levels induced by TDNPs, and normalized lipid profiles by reducing total cholesterol, triglycerides, and low-density lipoprotein cholesterol, while elevating high-density lipoprotein cholesterol. …”