The role of IRF-1 in mediating T-cell immune imbalance in systemic lupus erythematosus and the construction of a diagnostic model حسب Zichen Huang (6587885)

"…Immune analysis revealed decreased numbers of resting CD4⁺ memory T cells and Tregs (<i>P</i> < 0.01), alongside expanded proinflammatory cells (M1/M2 macrophages, neutrophils; <i>P</i> < 0.01). …"

Multifaceted roles of NADPH oxidases in the growth and pathogenicity of <i>Beauveria bassiana</i> حسب Shengan Zhu (19817727)

"…Expression analysis revealed significant upregulation of BbNoxs during fungal growth and infection. …"

Video 5_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 حسب Shirong Ruan (15414081)

"…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …"

Table 2_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.docx حسب Songtao Li (186776)

"…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…"

Image 2_Exploring the antibacterial and anti-biofilm properties of Diacerein against methicillin-resistant Staphylococcus aureus.tif حسب Yingying Sun (568696)

"…Background<p>Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant clinical challenge due to its multidrug resistance. …"

Different model detection results comparison. حسب Chunhua Yang (346871)

"…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …"

Table 5_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Video 6_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 حسب Shirong Ruan (15414081)

"…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …"

DataSheet1_Green degree decision and pricing strategy of dual-channel supply chains.docx حسب Xiaomeng Luo (6033479)

"…Thus, green degree decision has garnered significant attention from manufacturers. This paper incorporates green degree decisions into a dual-channel supply chain and adopts a Stackelberg model to analyze the green degree and pricing strategies under centralized and decentralized decisions. …"

Table 8_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Aetiology, clinical characteristics, and risk factors influencing mortality in patients with infective endocarditis: a retrospective study حسب Özkan Vural (21470515)

"…In-hospital mortality was 31.7%, and one-year mortality was 40.6%. A statistically significant difference in in-hospital mortality was found between combination therapy (23%) and medical therapy (40.8%). …"

Image5_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff حسب Alexandra Coello-Camba (6489533)

"…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …"

Table 3_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx حسب Zhengqing Yu (12641890)

"…Significant heterogeneity was detected in the pooled analysis and meta-regression analysis suggested that participants’ age and the prevalence of diabetes significantly accounted for the heterogeneity.…"

Table 1_Global, regional and national patterns and gender disparity of intraocular foreign bodies from 1990 to 2021.doc حسب Yi Shan (160293)

"…The age-standardized DALYs rates of males were significantly higher than those of females in all five SDI groups (p < 0.001) in 2021. …"

Data Sheet 1_Evaluating the therapeutic potential of BSA-reduced mussel-derived selenium nanoparticles to mitigate copper sulfate-induced hepatic damage and neurodegeneration in a... حسب Suganiya Umapathy (21383339)

"…Stabilized selenium nanoparticles reduced for 30 minutes (25 μg/ml) showed significant in vitro reactive oxygen species scavenging activity and improved in vivo antioxidant enzyme levels by decreasing lipid peroxidation and nitric oxide levels. …"

Table 1_A two-sample bidirectional Mendelian randomization analysis between telomere length and hyperthyroidism.xlsx حسب Shiben Zhu (19159465)

"…Utilizing 139 genome-wide significant single nucleotide polymorphisms (SNPs) as instrumental variables (IVs) for TL, forward MR analyses indicated a negative causal effect of TL on hyperthyroidism. …"

Image 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.tif حسب Wenbing Zhang (152972)

"…A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…"

Image 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... حسب Yangtian Jiao (21725018)

"…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …"

Table 1_Inequalities and age-period-cohort effects of global and regional burden for interstitial lung disease and pulmonary sarcoidosis: based on Global Burden of Disease study 20... حسب Lei Zhang (38117)

"…Background<p>Interstitial lung disease (ILD) and pulmonary sarcoidosis pose significant disease burdens on a global scale.</p>Methods<p>The underlying data was derived from the Global Burden of Disease (GBD) 2021 database. …"

Data Sheet 1_Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity.pdf حسب Vidushi Tyagi (14022240)

"…</p>Results<p>ApEtOH significantly downregulated the chemokines RANTES, MCP-1, and ENA-78, reducing the pro-inflammatory cytokines TNF-α and IL-6 in vitro. …"