يعرض 20,161 - 20,180 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant ((main decrease) OR (point decrease)) ))', وقت الاستعلام: 0.49s تنقيح النتائج
  1. 20161

    Table 1_Network pharmacology and experimental validation to elucidate the pharmacological mechanisms of OATF against kidney stones.xlsx حسب Sisi Dai (7837886)

    منشور في 2025
    "…In vitro experimental results demonstrated that OATF effectively protected HK-2 cells from oxidative stress, inhibited calcium oxalate crystal adhesion, and reduced apoptosis. In vivo, OATF significantly decreased serum creatinine (SCR), serum calcium (Ca), serum phosphorus (P), and blood urea nitrogen (BUN) levels in CaOx-induced Sprague-Dawley (SD) rats, indicating its protective effects against KS.…"
  2. 20162

    Image 4_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.tif حسب Yuanbing Zhu (20538638)

    منشور في 2025
    "…Differential gene expression and immune infiltration analysis showed that upstream transcription factors, including Forkhead box P3 (FOXP3), were significantly disrupted. In vitro cytology experiments, the results indicate that SIRT1 is activated in LPS induced inflammation, subsequently perturbing the Treg/Th17 immune balance axis. …"
  3. 20163

    Data_Sheet_1_The functions and factors governing fungal communities and diversity in agricultural waters: insights into the ecosystem services aquatic mycobiota provide.pdf حسب Phillip Pham (407350)

    منشور في 2024
    "…Agricultural land use was associated with decreased mycobiota alpha diversity and distinct fungal communities were observed at agricultural drainage ditch and mixed-land use sites compared to a forested site that had minimal anthropogenic activities in catchment. …"
  4. 20164

    Figure 2 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes حسب Laura Kuett (20493991)

    منشور في 2025
    "…<b>D,</b> Tumor cell phenotypic cluster enrichment in each metastatic patient group compared with average metastasis composition by differential abundance testing. Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change.…"
  5. 20165

    Image 4_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tiff حسب Asma Bibi (12057986)

    منشور في 2025
    "…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …"
  6. 20166

    Assembly process of machine recognition form. حسب Zhe Hu (787283)

    منشور في 2025
    "…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…"
  7. 20167

    Data Sheet 1_Spatiotemporal dynamics and influencing factors of native and invasive saltmarshes in a rapidly silting bay during 1985–2023.docx حسب Mingshan Xu (15370147)

    منشور في 2025
    "…Results showed that native saltmarshes significantly decreased from 632.24 ha to complete disappearance, while S. alterniflora expanded from zero to 2872.90 ha in Yueqing Bay during 1985-2023. …"
  8. 20168

    Negative Activation Volume in Hydrated BaZr<sub>0.8</sub>Y<sub>0.2</sub>O<sub>3−δ</sub> Proton Conductor at Room Temperature (Supporting Information) حسب Fumitada IGUCHI (20594488)

    منشور في 2025
    "…The bulk resistance of the material decreases as the pressure increases, with a decrement ratio from −0.6 to −2.3 % per 60 MPa variation in pressure. …"
  9. 20169

    Table 1_Epidemiological trends and disparities in iodine, vitamin A, and iron deficiencies among children aged 0–14 years globally, 1990–2021.doc حسب Fang Peng (327071)

    منشور في 2025
    "…Vitamin A deficiency incidence rate decreased by 94.9% (EAPC: −2.02), while DALY rates fell 92.8%. …"
  10. 20170

    Image 3_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif حسب Asma Bibi (12057986)

    منشور في 2025
    "…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …"
  11. 20171

    Incremental investment and maintenance costs. حسب Kai Wen (261662)

    منشور في 2025
    "…The results show that the system can effectively recover waste heat from the DC, significantly reducing cooling electricity consumption during the heating season and decreasing original heating steam consumption by about 25%. …"
  12. 20172

    Image 1_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif حسب Asma Bibi (12057986)

    منشور في 2025
    "…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …"
  13. 20173

    Table 1_Impact of feed availability on growth performance and amino acid utilization of cobia (Rachycentron canadum) at elevated temperature.docx حسب Minh-Hoang Le (20438495)

    منشور في 2024
    "…</p>Discussion<p>After six weeks, a 24-hour post-prandial analysis showed selective retention of some amino acids in muscle and plasma, but significantly higher retention in the liver at the higher temperature. …"
  14. 20174

    <b>SZC-6</b><b> Promotes Diabetic Wound Healing in Mice by Modulating M1/M2 Macrophage Ratio and Inhibiting MyD88/NF-κB Pathway</b> حسب 昂 轩 (20139579)

    منشور في 2024
    "…We also found that SZC-6 significantly reduced MyD88, p-IκBα, and p-P65 protein levels and inhibited the nuclear translocation of P65 in LPS-treated cells. …"
  15. 20175

    Supplementary file 1_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg حسب Yuhui Zhang (399617)

    منشور في 2025
    "…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
  16. 20176

    Data Sheet 2_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf حسب Lizhan Su (19936980)

    منشور في 2025
    "…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…"
  17. 20177

    Annual system costs and benefits. حسب Kai Wen (261662)

    منشور في 2025
    "…The results show that the system can effectively recover waste heat from the DC, significantly reducing cooling electricity consumption during the heating season and decreasing original heating steam consumption by about 25%. …"
  18. 20178

    Data Sheet 1_Comparative hepatoprotective effects of AMK and PAMK via Nrf2 signaling in broiler breeders.pdf حسب Baili Lu (21192662)

    منشور في 2025
    "…Both AMK and PAMK significantly reduced serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities compared to control. …"
  19. 20179

    Data_Sheet_1_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx حسب Rui Zhu (305217)

    منشور في 2024
    "…</p>Results<p>Compared with the HCs, NIID patients showed reduced mean kurtosis (MK), radial kurtosis (RK), axial kurtosis (AK), and kurtosis fractional anisotropy (KFA) values in deep gray matter regions. Significantly decreased MK, RK, AK, KFA and fractional anisotropy (FA), and increased mean diffusivity (MD) values were observed in extensive white matter fiber tracts. …"
  20. 20180

    Image 6_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg حسب Jie Li (15030)

    منشور في 2025
    "…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …"