Image 1_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... by Chase Garcia (21803576)

“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”

DataSheet2_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf by Bo Yao (308010)

“…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…”

Supplementary file 1_Emergency department overcrowding: first Swiss application of the Emergency Department Work Index and risk factors for overcrowding.pdf by Aline Herzog (22589720)

“…Introduction<p>Emergency department (ED) overcrowding is associated with increased waiting time, reduced patient satisfaction, and decreased quality of care. Numerous validated scores are available for assessing ED overcrowding. …”

Dataset with steel insert. by Briya Tariq (19666901)

“…It focuses on identifying and quantifying clinically significant materials in the presence of metal objects. …”

Table 2_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.xlsx by Nan Jiang (21252)

“…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …”

Image 1_Lower hippocampal volumes at baseline are associated with higher volume loss in healthy elderly.png by Vivian Schultz (17379235)

“…No covariates significantly influenced this association (p > 0.05).…”

Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx by Yu Zhou (89766)

“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”

Reference dataset. by Briya Tariq (19666901)

“…It focuses on identifying and quantifying clinically significant materials in the presence of metal objects. …”

Data Sheet 1_Increased circulating levels of SP-D and IL-10 are associated with the development of disease severity and pulmonary fibrosis in patients with COVID-19.pdf by Xin Pan (3712768)

“…Among the biomarkers indicative of macrophage polarization, compared to non-ARDS patients, a significant increase in IL-10, Inducible nitric oxide synthase (iNOS), and Arginase-1 (Arg-1) were observed in ARDS patients, while Tumor necrosis factor-α (TNF-α) was decreased. …”

Data Sheet 1_Association of cardiovascular health with COPD (NHANES 2007-2020): mediating potential of lean body mass.docx by Ruoyu Gou (11835929)

“…</p>Conclusions<p>Higher LC9 scores, particularly when accompanied by increased LBM levels, showed significant associations with reduced COPD risk in cross-sectional analyses.…”

Supplementary file 1_Evaluation of drug interactions in outpatients taking antipsychotic medications.docx by Bshra A. Alsfouk (13259895)

“…The most frequent potential adverse effects were increased sedation (36%), hyperglycemia (15%) and decreased blood pressure (14%). Receiving polypharmacy (i.e., ≥5 drugs concomitantly administered) was significantly associated with an increased probability of drug interaction occurrence (OR = 42, P = 0.0026). …”

Image 2_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff by Haoming Shen (3816988)

“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”

Data Sheet 2_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont... by Shi-Bing Liang (10200806)

“…Adding TXL to WM showed a non-significant trend toward reducing myocardial infarction [RR 0.34, 95% CI (0.05, 2.12); NNT = 41] and sudden cardiac death [RR 0.34, 95% CI (0.01, 8.28); NNT = 65]. …”

Table2_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx by J. Riera-Arnau (20431328)

“…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …”

Yeast strains used in this study. by Hilary T. Brewis (11798006)

“…Furthermore, as H2A.Z mutants only display significant growth defects in genotoxic stress conditions, a more substantive role for H2A.Z in gene expression may only be uncovered after exposure to cellular stress. …”

Table 1_Trend analysis of pediatric urolithiasis prevalence from 1990 to 2021 in the BRICS.docx by Zhi-gang Zhang (328212)

“…Finally, China has made significant progress in the prevention and control of pediatric urolithiasis over the past 30 years and is expected to continue this positive trend over the next 15 years.…”

Counting results on MTDC-UAV dataset. by Dunlu Lu (19964225)

“…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …”

Data Sheet 1_The prevalence and antimicrobial resistance of respiratory pathogens isolated from feedlot cattle in Canada.zip by Porjai Rattanapanadda (7577912)

“…Resistance was higher in calves than in yearlings for tulathromycin in H. somni, and for gamithromycin, spectinomycin, tulathromycin, tildipirosin, and tetracycline for P. multocida (p < 0.05) Resistance to tetracycline, tildipirosin, and tulathromycin decreased between 61–80 DOF and 81–100 DOF when compared to 20–40 DOF, whereas for spectinomycin, resistance was lower in cattle sampled between 61–80 DOF than those sampled at 20–40 DOF for P. multocida.…”

Data Sheet 1_Liuweizhiji Gegen-Sangshen beverage protects against alcoholic liver disease in mice through the gut microbiota mediated SCFAs/GPR43/GLP-1 pathway.docx by Mingyun Tang (20226342)

“…LGS significantly improved liver steatosis, enhanced activities of alcohol metabolizing enzymes (ALDH and ADH), and reduced the CYP2E1 activity. …”

Table 5_Analyze agricultural efficiency and influencing factors base on the three-stage DEA model and Malmquist index.xlsx by Lin-Feng Wang (10944843)

“…TFP peaks at 1.157 (increased by 15.7%) in 2019 and declines to 0.978 (decreased by 2.2%) from 2020 to 2021 due to global economic slowdowns. …”